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Improvement of Topical Palmitoylethanolamide Anti-Inflammatory Activity by Pegylated Prodrugs.
Tronino D, Russo R, Ostacolo C, Mazzolari A, De Caro C, Avagliano C, Laneri S, La Rana G, Sacchi A, Della Valle F, Vistoli G, Calignano A. Tronino D, et al. Among authors: La Rana G. Mol Pharm. 2015 Sep 8;12(9):3369-79. doi: 10.1021/acs.molpharmaceut.5b00397. Epub 2015 Aug 24. Mol Pharm. 2015. PMID: 26289562
The search for the palmitoylethanolamide receptor.
LoVerme J, La Rana G, Russo R, Calignano A, Piomelli D. LoVerme J, et al. Among authors: La Rana G. Life Sci. 2005 Aug 19;77(14):1685-98. doi: 10.1016/j.lfs.2005.05.012. Life Sci. 2005. PMID: 15963531 Review.
Modulation of anxiety through blockade of anandamide hydrolysis.
Kathuria S, Gaetani S, Fegley D, ValiƱo F, Duranti A, Tontini A, Mor M, Tarzia G, La Rana G, Calignano A, Giustino A, Tattoli M, Palmery M, Cuomo V, Piomelli D. Kathuria S, et al. Among authors: La Rana G. Nat Med. 2003 Jan;9(1):76-81. doi: 10.1038/nm803. Epub 2002 Dec 2. Nat Med. 2003. PMID: 12461523
Palmitoylethanolamide modulates pentobarbital-evoked hypnotic effect in mice: involvement of allopregnanolone biosynthesis.
Sasso O, La Rana G, Vitiello S, Russo R, D'Agostino G, Iacono A, Russo E, Citraro R, Cuzzocrea S, Piazza PV, De Sarro G, Meli R, Calignano A. Sasso O, et al. Among authors: La Rana G. Eur Neuropsychopharmacol. 2010 Mar;20(3):195-206. doi: 10.1016/j.euroneuro.2009.09.003. Epub 2009 Oct 27. Eur Neuropsychopharmacol. 2010. PMID: 19864116
Central administration of palmitoylethanolamide reduces hyperalgesia in mice via inhibition of NF-kappaB nuclear signalling in dorsal root ganglia.
D'Agostino G, La Rana G, Russo R, Sasso O, Iacono A, Esposito E, Mattace Raso G, Cuzzocrea S, Loverme J, Piomelli D, Meli R, Calignano A. D'Agostino G, et al. Among authors: La Rana G. Eur J Pharmacol. 2009 Jun 24;613(1-3):54-9. doi: 10.1016/j.ejphar.2009.04.022. Epub 2009 Apr 20. Eur J Pharmacol. 2009. PMID: 19386271
Acute intracerebroventricular administration of palmitoylethanolamide, an endogenous peroxisome proliferator-activated receptor-alpha agonist, modulates carrageenan-induced paw edema in mice.
D'Agostino G, La Rana G, Russo R, Sasso O, Iacono A, Esposito E, Raso GM, Cuzzocrea S, Lo Verme J, Piomelli D, Meli R, Calignano A. D'Agostino G, et al. Among authors: La Rana G. J Pharmacol Exp Ther. 2007 Sep;322(3):1137-43. doi: 10.1124/jpet.107.123265. Epub 2007 Jun 12. J Pharmacol Exp Ther. 2007. PMID: 17565008
The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice.
Russo R, Loverme J, La Rana G, Compton TR, Parrott J, Duranti A, Tontini A, Mor M, Tarzia G, Calignano A, Piomelli D. Russo R, et al. Among authors: La Rana G. J Pharmacol Exp Ther. 2007 Jul;322(1):236-42. doi: 10.1124/jpet.107.119941. Epub 2007 Apr 5. J Pharmacol Exp Ther. 2007. PMID: 17412883
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