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Chk2 activates E2F-1 in response to DNA damage.
Stevens C, Smith L, La Thangue NB. Stevens C, et al. Nat Cell Biol. 2003 May;5(5):401-9. doi: 10.1038/ncb974. Nat Cell Biol. 2003. PMID: 12717439
Cofactor Strap regulates oxidative phosphorylation and mitochondrial p53 activity through ATP synthase.
Maniam S, Coutts AS, Stratford MR, McGouran J, Kessler B, La Thangue NB. Maniam S, et al. Cell Death Differ. 2015 Jan;22(1):156-63. doi: 10.1038/cdd.2014.135. Epub 2014 Aug 29. Cell Death Differ. 2015. PMID: 25168243 Free PMC article.
A regulatory circuit that involves HR23B and HDAC6 governs the biological response to HDAC inhibitors.
New M, Olzscha H, Liu G, Khan O, Stimson L, McGouran J, Kerr D, Coutts A, Kessler B, Middleton M, La Thangue NB. New M, et al. Cell Death Differ. 2013 Oct;20(10):1306-16. doi: 10.1038/cdd.2013.47. Epub 2013 May 24. Cell Death Differ. 2013. PMID: 23703321 Free PMC article.
Diversity within the pRb pathway: is there a code of conduct?
Munro S, Carr SM, La Thangue NB. Munro S, et al. Oncogene. 2012 Oct 4;31(40):4343-52. doi: 10.1038/onc.2011.603. Epub 2012 Jan 16. Oncogene. 2012. PMID: 22249267 Review.
E2F-1 regulation by an unusual DNA damage-responsive DP partner subunit.
Ingram L, Munro S, Coutts AS, La Thangue NB. Ingram L, et al. Cell Death Differ. 2011 Jan;18(1):122-32. doi: 10.1038/cdd.2010.70. Epub 2010 Jun 18. Cell Death Differ. 2011. PMID: 20559320 Free PMC article.
Control of gene expression and the cell cycle.
Chan HM, Shikama N, La Thangue NB. Chan HM, et al. Essays Biochem. 2001;37:87-96. doi: 10.1042/bse0370087. Essays Biochem. 2001. PMID: 11758459 Review.
p300/CBP proteins: HATs for transcriptional bridges and scaffolds.
Chan HM, La Thangue NB. Chan HM, et al. J Cell Sci. 2001 Jul;114(Pt 13):2363-73. J Cell Sci. 2001. PMID: 11559745 Review.
A TPR motif cofactor contributes to p300 activity in the p53 response.
Demonacos C, Krstic-Demonacos M, La Thangue NB. Demonacos C, et al. Mol Cell. 2001 Jul;8(1):71-84. doi: 10.1016/s1097-2765(01)00277-5. Mol Cell. 2001. PMID: 11511361
Acetylation control of the retinoblastoma tumour-suppressor protein.
Chan HM, Krstic-Demonacos M, Smith L, Demonacos C, La Thangue NB. Chan HM, et al. Nat Cell Biol. 2001 Jul;3(7):667-74. doi: 10.1038/35083062. Nat Cell Biol. 2001. PMID: 11433299
Functional interaction between nucleosome assembly proteins and p300/CREB-binding protein family coactivators.
Shikama N, Chan HM, Krstic-Demonacos M, Smith L, Lee CW, Cairns W, La Thangue NB. Shikama N, et al. Mol Cell Biol. 2000 Dec;20(23):8933-43. doi: 10.1128/mcb.20.23.8933-8943.2000. Mol Cell Biol. 2000. PMID: 11073993 Free PMC article.
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