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Evolution of Escherichia coli to 42 °C and subsequent genetic engineering reveals adaptive mechanisms and novel mutations.
Mol Biol Evol. 2014 Oct;31(10):2647-62. doi: 10.1093/molbev/msu209. Epub 2014 Jul 10.
Mol Biol Evol. 2014.
PMID: 25015645
Free PMC article.
Use of adaptive laboratory evolution to discover key mutations enabling rapid growth of Escherichia coli K-12 MG1655 on glucose minimal medium.
LaCroix RA, Sandberg TE, O'Brien EJ, Utrilla J, Ebrahim A, Guzman GI, Szubin R, Palsson BO, Feist AM.
LaCroix RA, et al.
Appl Environ Microbiol. 2015 Jan;81(1):17-30. doi: 10.1128/AEM.02246-14. Epub 2014 Oct 10.
Appl Environ Microbiol. 2015.
PMID: 25304508
Free PMC article.
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A Model for Designing Adaptive Laboratory Evolution Experiments.
LaCroix RA, Palsson BO, Feist AM.
LaCroix RA, et al.
Appl Environ Microbiol. 2017 Mar 31;83(8):e03115-16. doi: 10.1128/AEM.03115-16. Print 2017 Apr 15.
Appl Environ Microbiol. 2017.
PMID: 28159796
Free PMC article.
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Enzyme promiscuity shapes adaptation to novel growth substrates.
Guzmán GI, Sandberg TE, LaCroix RA, Nyerges Á, Papp H, de Raad M, King ZA, Hefner Y, Northen TR, Notebaart RA, Pál C, Palsson BO, Papp B, Feist AM.
Guzmán GI, et al. Among authors: lacroix ra.
Mol Syst Biol. 2019 Apr 8;15(4):e8462. doi: 10.15252/msb.20188462.
Mol Syst Biol. 2019.
PMID: 30962359
Free PMC article.
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Laboratory evolution reveals a two-dimensional rate-yield tradeoff in microbial metabolism.
Cheng C, O'Brien EJ, McCloskey D, Utrilla J, Olson C, LaCroix RA, Sandberg TE, Feist AM, Palsson BO, King ZA.
Cheng C, et al. Among authors: lacroix ra.
PLoS Comput Biol. 2019 Jun 3;15(6):e1007066. doi: 10.1371/journal.pcbi.1007066. eCollection 2019 Jun.
PLoS Comput Biol. 2019.
PMID: 31158228
Free PMC article.
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