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IL-6 Trans-Signaling Is Increased in Diabetes, Impacted by Glucolipotoxicity, and Associated With Liver Stiffness and Fibrosis in Fatty Liver Disease.
Gunes A, Schmitt C, Bilodeau L, Huet C, Belblidia A, Baldwin C, Giard JM, Biertho L, Lafortune A, Couture CY, Cheung A, Nguyen BN, Galun E, Bémeur C, Bilodeau M, Laplante M, Tang A, Faraj M, Estall JL. Gunes A, et al. Among authors: laplante m. Diabetes. 2023 Dec 1;72(12):1820-1834. doi: 10.2337/db23-0171. Diabetes. 2023. PMID: 37757741 Free PMC article.
SHP-1 phosphatase acts as a coactivator of PCK1 transcription to control gluconeogenesis.
Kumar A, Schwab M, Laborit Labrada B, Silveira MAD, Goudreault M, Fournier É, Bellmann K, Beauchemin N, Gingras AC, Bilodeau S, Laplante M, Marette A. Kumar A, et al. Among authors: laplante m. J Biol Chem. 2023 Sep;299(9):105164. doi: 10.1016/j.jbc.2023.105164. Epub 2023 Aug 16. J Biol Chem. 2023. PMID: 37595871 Free PMC article.
mTORC1 takes control of lysosomal lipid breakdown.
Tribouillard L, Laplante M. Tribouillard L, et al. Among authors: laplante m. Nat Metab. 2022 Dec;4(12):1620-1622. doi: 10.1038/s42255-022-00702-w. Nat Metab. 2022. PMID: 36536135 No abstract available.
Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1.
Shin HR, Citron YR, Wang L, Tribouillard L, Goul CS, Stipp R, Sugasawa Y, Jain A, Samson N, Lim CY, Davis OB, Castaneda-Carpio D, Qian M, Nomura DK, Perera RM, Park E, Covey DF, Laplante M, Evers AS, Zoncu R. Shin HR, et al. Among authors: laplante m. Science. 2022 Sep 16;377(6612):1290-1298. doi: 10.1126/science.abg6621. Epub 2022 Aug 25. Science. 2022. PMID: 36007018 Free PMC article.
ZNF768: controlling cellular senescence and proliferation with ten fingers.
Villot R, Poirier A, Devillers R, Kolnoguz A, Elowe S, Manem VSK, Joubert P, Mallette FA, Laplante M. Villot R, et al. Among authors: laplante m. Mol Cell Oncol. 2021 Dec 8;8(6):1985930. doi: 10.1080/23723556.2021.1985930. eCollection 2021. Mol Cell Oncol. 2021. PMID: 35419475 Free PMC article.
Adipocyte-specific Nos2 deletion improves insulin resistance and dyslipidemia through brown fat activation in diet-induced obese mice.
Vilela VR, Samson N, Nachbar R, Perazza LR, Lachance G, Rokatoarivelo V, Centano-Baez C, Zancan P, Sola-Penna M, Bellmann K, Di Marzo V, Laplante M, Marette A. Vilela VR, et al. Among authors: laplante m. Mol Metab. 2022 Mar;57:101437. doi: 10.1016/j.molmet.2022.101437. Epub 2022 Jan 14. Mol Metab. 2022. PMID: 35033724 Free PMC article.
159 results