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Transcriptional Regulation in Prostate Cancer.

Labbé DP, Brown M. Labbé DP, et al. Cold Spring Harb Perspect Med. 2018 Nov 1;8(11):a030437. doi: 10.1101/cshperspect.a030437. Cold Spring Harb Perspect Med. 2018. PMID: 29530947 Free PMC article. Review.

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Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance.

Ku SY, Rosario S, Wang Y, Mu P, Seshadri M, Goodrich ZW, Goodrich MM, Labbé DP, Gomez EC, Wang J, Long HW, Xu B, Brown M, Loda M, Sawyers CL, Ellis L, Goodrich DW. Ku SY, et al. Among authors: labbe dp. Science. 2017 Jan 6;355(6320):78-83. doi: 10.1126/science.aah4199. Science. 2017. PMID: 28059767 Free PMC article.

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High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program.

Labbé DP, Zadra G, Yang M, Reyes JM, Lin CY, Cacciatore S, Ebot EM, Creech AL, Giunchi F, Fiorentino M, Elfandy H, Syamala S, Karoly ED, Alshalalfa M, Erho N, Ross A, Schaeffer EM, Gibb EA, Takhar M, Den RB, Lehrer J, Karnes RJ, Freedland SJ, Davicioni E, Spratt DE, Ellis L, Jaffe JD, DʼAmico AV, Kantoff PW, Bradner JE, Mucci LA, Chavarro JE, Loda M, Brown M. Labbé DP, et al. Nat Commun. 2019 Sep 25;10(1):4358. doi: 10.1038/s41467-019-12298-z. Nat Commun. 2019. PMID: 31554818 Free PMC article.

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TOP2A and EZH2 Provide Early Detection of an Aggressive Prostate Cancer Subgroup.

Labbé DP, Sweeney CJ, Brown M, Galbo P, Rosario S, Wadosky KM, Ku SY, Sjöström M, Alshalalfa M, Erho N, Davicioni E, Karnes RJ, Schaeffer EM, Jenkins RB, Den RB, Ross AE, Bowden M, Huang Y, Gray KP, Feng FY, Spratt DE, Goodrich DW, Eng KH, Ellis L. Labbé DP, et al. Clin Cancer Res. 2017 Nov 15;23(22):7072-7083. doi: 10.1158/1078-0432.CCR-17-0413. Epub 2017 Sep 12. Clin Cancer Res. 2017. PMID: 28899973 Free PMC article.

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Evidence that EZH2 Deregulation is an Actionable Therapeutic Target for Prevention of Prostate Cancer.

Burkhart DL, Morel KL, Wadosky KM, Labbé DP, Galbo PM, Dalimov Z, Xu B, Loda M, Ellis L. Burkhart DL, et al. Among authors: labbe dp. Cancer Prev Res (Phila). 2020 Dec;13(12):979-988. doi: 10.1158/1940-6207.CAPR-20-0186. Epub 2020 Sep 11. Cancer Prev Res (Phila). 2020. PMID: 32917647

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Proteases and their inhibitors as prognostic factors for high-grade serous ovarian cancer.

Trudel D, Avarvarei LM, Orain M, Turcotte S, Plante M, Grégoire J, Kappelhoff R, Labbé DP, Bachvarov D, Têtu B, Overall CM, Bairati I. Trudel D, et al. Among authors: labbe dp. Pathol Res Pract. 2019 Jun;215(6):152369. doi: 10.1016/j.prp.2019.02.019. Epub 2019 Mar 2. Pathol Res Pract. 2019. PMID: 30987833

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Role of diet in prostate cancer: the epigenetic link.

Labbé DP, Zadra G, Ebot EM, Mucci LA, Kantoff PW, Loda M, Brown M. Labbé DP, et al. Oncogene. 2015 Sep 3;34(36):4683-91. doi: 10.1038/onc.2014.422. Epub 2014 Dec 22. Oncogene. 2015. PMID: 25531313 Free PMC article. Review.

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Protein tyrosine phosphatases in cancer: friends and foes!

Labbé DP, Hardy S, Tremblay ML. Labbé DP, et al. Prog Mol Biol Transl Sci. 2012;106:253-306. doi: 10.1016/B978-0-12-396456-4.00009-2. Prog Mol Biol Transl Sci. 2012. PMID: 22340721 Review.

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Green tea for ovarian cancer prevention and treatment: a systematic review of the in vitro, in vivo and epidemiological studies.

Trudel D, Labbé DP, Bairati I, Fradet V, Bazinet L, Têtu B. Trudel D, et al. Among authors: labbe dp. Gynecol Oncol. 2012 Sep;126(3):491-8. doi: 10.1016/j.ygyno.2012.04.048. Epub 2012 May 4. Gynecol Oncol. 2012. PMID: 22564714 Review.

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ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer.

Deblois G, Smith HW, Tam IS, Gravel SP, Caron M, Savage P, Labbé DP, Bégin LR, Tremblay ML, Park M, Bourque G, St-Pierre J, Muller WJ, Giguère V. Deblois G, et al. Among authors: labbe dp. Nat Commun. 2016 Jul 12;7:12156. doi: 10.1038/ncomms12156. Nat Commun. 2016. PMID: 27402251 Free PMC article.

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