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Preservatives in eyedrops: the good, the bad and the ugly.
Baudouin C, Labbé A, Liang H, Pauly A, Brignole-Baudouin F. Baudouin C, et al. Among authors: labbe a. Prog Retin Eye Res. 2010 Jul;29(4):312-34. doi: 10.1016/j.preteyeres.2010.03.001. Epub 2010 Mar 17. Prog Retin Eye Res. 2010. PMID: 20302969
Preservative-induced adverse effects are therefore far from being restricted to only allergic reactions, and side effects are often very difficult to identify because they mostly occur in a delayed or poorly specific manner. Care should therefore be taken to avoid the long …
Preservative-induced adverse effects are therefore far from being restricted to only allergic reactions, and side effects are often very dif …
[In vivo confocal microscopy and ocular surface diseases: anatomical-clinical correlations].
De Nicola R, Labbé A, Amar N, Dupas B, Baudouin C. De Nicola R, et al. Among authors: labbe a. J Fr Ophtalmol. 2005 Sep;28(7):691-8. doi: 10.1016/s0181-5512(05)80980-5. J Fr Ophtalmol. 2005. PMID: 16208218 French.
In keratoconjunctivitis sicca, we found squamous metaplasia, inflammatory cell infiltration, goblet cell depletion, as well as a nuclear snake-like chromatin pattern. ...In vivo confocal microscopy, showing corneal and conjunctival epithelial structures in the live eye at …
In keratoconjunctivitis sicca, we found squamous metaplasia, inflammatory cell infiltration, goblet cell depletion, as well as a nucl …
Comparative anatomy of laboratory animal corneas with a new-generation high-resolution in vivo confocal microscope.
Labbé A, Liang H, Martin C, Brignole-Baudouin F, Warnet JM, Baudouin C. Labbé A, et al. Curr Eye Res. 2006 Jun;31(6):501-9. doi: 10.1080/02713680600701513. Curr Eye Res. 2006. PMID: 16769609
PURPOSE: The aim of the current study was to compare the corneas of three commonly used laboratory animals with a new in vivo confocal microscope. ...Besides endothelial cell density, the endothelium was similar among the three animals and was seen as hyper-reflective cell …
PURPOSE: The aim of the current study was to compare the corneas of three commonly used laboratory animals with a new in vivo confoca …
Comparison of toxicological profiles of benzalkonium chloride and polyquaternium-1: an experimental study.
Labbé A, Pauly A, Liang H, Brignole-Baudouin F, Martin C, Warnet JM, Baudouin C. Labbé A, et al. J Ocul Pharmacol Ther. 2006 Aug;22(4):267-78. doi: 10.1089/jop.2006.22.267. J Ocul Pharmacol Ther. 2006. PMID: 16910868
PURPOSE: The aim of this study was to compare, in vivo on a rat model, two different preservatives- benzalkonium chloride (BAC) and polyquaternium-1 (PQ-1)-using new experimental approaches. ...Rats were randomly divided into five groups instilled twice a day for 11 …
PURPOSE: The aim of this study was to compare, in vivo on a rat model, two different preservatives- benzalkonium chloride (BAC) and p …
In vivo confocal microscopy and ex vivo flow cytometry: new tools for assessing ocular inflammation applied to rabbit lipopolysaccharide-induced conjunctivitis.
Liang H, Baudouin C, Labbé A, Pauly A, Martin C, Warnet JM, Brignole-Baudouin F. Liang H, et al. Among authors: labbe a. Mol Vis. 2006 Nov 16;12:1392-402. Mol Vis. 2006. PMID: 17149365
PURPOSE: Lipopolysaccharide (LPS) may act as a key stimulatory agent in ocular surface diseases (OSDs) through TNF-alpha release. ...A neutralizing anti-TNF-alpha antibody was used to assess the role of TNF-alpha. RESULTS: In vivo CM provided high-resolution images …
PURPOSE: Lipopolysaccharide (LPS) may act as a key stimulatory agent in ocular surface diseases (OSDs) through TNF-alpha release. ... …
[Ocular surface investigations in dry eye].
Labbé A, Brignole-Baudouin F, Baudouin C. Labbé A, et al. J Fr Ophtalmol. 2007 Jan;30(1):76-97. doi: 10.1016/s0181-5512(07)89557-x. J Fr Ophtalmol. 2007. PMID: 17287676 Review. French.
Dry eye is a complex clinicopathological entity involving tear film, lacrimal glands, eyelids, and a wide spectrum of ocular surface cells, including epithelial, inflammatory, immune, and goblet cells. ...At the level of ocular surface cells, impression cytology rem …
Dry eye is a complex clinicopathological entity involving tear film, lacrimal glands, eyelids, and a wide spectrum of ocular s …
[Wound healing modulation in glaucoma surgery].
Labbé A, Khammari C, Baudouin C. Labbé A, et al. J Fr Ophtalmol. 2007 Jun;30(6):631-46. doi: 10.1016/s0181-5512(07)89673-2. J Fr Ophtalmol. 2007. PMID: 17646754 Review. French.
LPS-stimulated inflammation and apoptosis in corneal injury models.
Liang H, Brignole-Baudouin F, Labbé A, Pauly A, Warnet JM, Baudouin C. Liang H, et al. Among authors: labbe a. Mol Vis. 2007 Jul 17;13:1169-80. Mol Vis. 2007. PMID: 17679944
PURPOSE: To evaluate and compare the proinflammatory and apoptotic effects of lipopolysaccharide (LPS) in three rabbit corneal injury models using a new in vivo confocal microscope (IVCM) and immunohistological techniques. ...CONCLUSIONS: These results indicate that in var …
PURPOSE: To evaluate and compare the proinflammatory and apoptotic effects of lipopolysaccharide (LPS) in three rabbit corneal injury models …
New tools for the evaluation of toxic ocular surface changes in the rat.
Pauly A, Brignole-Baudouin F, Labbé A, Liang H, Warnet JM, Baudouin C. Pauly A, et al. Among authors: labbe a. Invest Ophthalmol Vis Sci. 2007 Dec;48(12):5473-83. doi: 10.1167/iovs.06-0728. Invest Ophthalmol Vis Sci. 2007. PMID: 18055795
The cornea was examined with the slit lamp, a fluorescein test was performed, and a confocal microscope was used in vivo to calculate corneal thickness, score corneal epithelial and endothelial defects, and quantify corneal stromal inflammation and neovascularizatio …
The cornea was examined with the slit lamp, a fluorescein test was performed, and a confocal microscope was used in vivo to ca …
Filtering blebs and aqueous pathway an immunocytological and in vivo confocal microscopy study.
Amar N, Labbé A, Hamard P, Dupas B, Baudouin C. Amar N, et al. Among authors: labbe a. Ophthalmology. 2008 Jul;115(7):1154-1161.e4. doi: 10.1016/j.ophtha.2007.10.024. Epub 2007 Dec 21. Ophthalmology. 2008. PMID: 18096232
Using in vivo confocal microscopy, all functioning blebs showed numerous intraepithelial optically empty microcysts, whereas nonfunctioning blebs had none or only a few. ...CONCLUSION: Impression cytology and in vivo confocal microscopy provide a new approach to fil …
Using in vivo confocal microscopy, all functioning blebs showed numerous intraepithelial optically empty microcysts, whereas nonfunctioning …
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