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Class-B GPCR activation: is ligand helix-capping the key?
Neumann JM, Couvineau A, Murail S, Lacapère JJ, Jamin N, Laburthe M. Neumann JM, et al. Among authors: laburthe m. Trends Biochem Sci. 2008 Jul;33(7):314-9. doi: 10.1016/j.tibs.2008.05.001. Epub 2008 Jun 12. Trends Biochem Sci. 2008. PMID: 18555686
Identification of cytoplasmic domains of hVPAC1 receptor required for activation of adenylyl cyclase. Crucial role of two charged amino acids strictly conserved in class II G protein-coupled receptors.
Couvineau A, Lacapere JJ, Tan YV, Rouyer-Fessard C, Nicole P, Laburthe M. Couvineau A, et al. Among authors: laburthe m. J Biol Chem. 2003 Jul 4;278(27):24759-66. doi: 10.1074/jbc.M301916200. Epub 2003 Apr 10. J Biol Chem. 2003. PMID: 12690118
The role of the N-terminal extracellular domain of hVPAC1 receptor for VIP binding is now established (Laburthe, M., Couvineau, A. and Marie, J. C. (2002) Recept. Channels 8, 137-153), but nothing is known regarding the cytoplasmic domains responsible for AC activat …
The role of the N-terminal extracellular domain of hVPAC1 receptor for VIP binding is now established (Laburthe, M., Couvineau …
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