Laburthe M - Search Results

1

The family B1 GPCR: structural aspects and interaction with accessory proteins.

Couvineau A, Laburthe M. Couvineau A, et al. Among authors: laburthe m. Curr Drug Targets. 2012 Jan;13(1):103-15. doi: 10.2174/138945012798868434. Curr Drug Targets. 2012. PMID: 21777182 Review.

2

The orexin receptor OX(1)R in colon cancer: a promising therapeutic target and a new paradigm in G protein-coupled receptor signalling through ITIMs.

Laburthe M, Voisin T. Laburthe M, et al. Br J Pharmacol. 2012 Mar;165(6):1678-1687. doi: 10.1111/j.1476-5381.2011.01510.x. Br J Pharmacol. 2012. PMID: 21627633 Free PMC article. Review.

3

Discovery of a functional immunoreceptor tyrosine-based switch motif in a 7-transmembrane-spanning receptor: role in the orexin receptor OX1R-driven apoptosis.

El Firar A, Voisin T, Rouyer-Fessard C, Ostuni MA, Couvineau A, Laburthe M. El Firar A, et al. Among authors: laburthe m. FASEB J. 2009 Dec;23(12):4069-80. doi: 10.1096/fj.09-131367. Epub 2009 Aug 6. FASEB J. 2009. PMID: 19661287

4

Class-B GPCR activation: is ligand helix-capping the key?

Neumann JM, Couvineau A, Murail S, Lacapère JJ, Jamin N, Laburthe M. Neumann JM, et al. Among authors: laburthe m. Trends Biochem Sci. 2008 Jul;33(7):314-9. doi: 10.1016/j.tibs.2008.05.001. Epub 2008 Jun 12. Trends Biochem Sci. 2008. PMID: 18555686

5

Peptide agonist docking in the N-terminal ectodomain of a class II G protein-coupled receptor, the VPAC1 receptor. Photoaffinity, NMR, and molecular modeling.

Tan YV, Couvineau A, Murail S, Ceraudo E, Neumann JM, Lacapère JJ, Laburthe M. Tan YV, et al. Among authors: laburthe m. J Biol Chem. 2006 May 5;281(18):12792-8. doi: 10.1074/jbc.M513305200. Epub 2006 Mar 6. J Biol Chem. 2006. PMID: 16520374

6

Identification of cytoplasmic domains of hVPAC1 receptor required for activation of adenylyl cyclase. Crucial role of two charged amino acids strictly conserved in class II G protein-coupled receptors.

Couvineau A, Lacapere JJ, Tan YV, Rouyer-Fessard C, Nicole P, Laburthe M. Couvineau A, et al. Among authors: laburthe m. J Biol Chem. 2003 Jul 4;278(27):24759-66. doi: 10.1074/jbc.M301916200. Epub 2003 Apr 10. J Biol Chem. 2003. PMID: 12690118

The role of the N-terminal extracellular domain of hVPAC1 receptor for VIP binding is now established (Laburthe, M., Couvineau, A. and Marie, J. C. (2002) Recept. Channels 8, 137-153), but nothing is known regarding the cytoplasmic domains responsible for AC activat …

The role of the N-terminal extracellular domain of hVPAC1 receptor for VIP binding is now established (Laburthe, M., Couvineau …

7

Characterization of the new photoaffinity probe (Bz2-K24)-VIP.

Tan YV, Couvineau A, Lacapere JJ, Laburthe M. Tan YV, et al. Among authors: laburthe m. Ann N Y Acad Sci. 2006 Jul;1070:575-80. doi: 10.1196/annals.1317.084. Ann N Y Acad Sci. 2006. PMID: 16888228

8

The human VPAC1 receptor: identification of the N-terminal ectodomain as a major VIP-binding site by photoaffinity labeling and 3D modeling.

Couvineau A, Tan YV, Ceraudo E, Lacapère JJ, Murail S, Neumann JM, Laburthe M. Couvineau A, et al. Among authors: laburthe m. Ann N Y Acad Sci. 2006 Jul;1070:205-9. doi: 10.1196/annals.1317.015. Ann N Y Acad Sci. 2006. PMID: 16888167

9

Strategies for studying the ligand binding site of GPCRs: photoaffinity labeling of the VPAC1 receptor, a prototype of class B GPCRs.

Couvineau A, Tan YV, Ceraudo E, Laburthe M. Couvineau A, et al. Among authors: laburthe m. Methods Enzymol. 2013;520:219-37. doi: 10.1016/B978-0-12-391861-1.00010-1. Methods Enzymol. 2013. PMID: 23332702

10

Aberrant expression of proteinase-activated receptor 4 promotes colon cancer cell proliferation through a persistent signaling that involves Src and ErbB-2 kinase.

Gratio V, Walker F, Lehy T, Laburthe M, Darmoul D. Gratio V, et al. Among authors: laburthe m. Int J Cancer. 2009 Apr 1;124(7):1517-25. doi: 10.1002/ijc.24070. Int J Cancer. 2009. PMID: 19058300

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