Lachmann N - Search Results

1

Gene correction of human induced pluripotent stem cells repairs the cellular phenotype in pulmonary alveolar proteinosis.

Lachmann N, Happle C, Ackermann M, Lüttge D, Wetzke M, Merkert S, Hetzel M, Kensah G, Jara-Avaca M, Mucci A, Skuljec J, Dittrich AM, Pfaff N, Brennig S, Schambach A, Steinemann D, Göhring G, Cantz T, Martin U, Schwerk N, Hansen G, Moritz T. Lachmann N, et al. Am J Respir Crit Care Med. 2014 Jan 15;189(2):167-82. doi: 10.1164/rccm.201306-1012OC. Am J Respir Crit Care Med. 2014. PMID: 24279725

2

Efficient hematopoietic redifferentiation of induced pluripotent stem cells derived from primitive murine bone marrow cells.

Pfaff N, Lachmann N, Kohlscheen S, Sgodda M, Araúzo-Bravo MJ, Greber B, Kues W, Glage S, Baum C, Niemann H, Schambach A, Cantz T, Moritz T. Pfaff N, et al. Among authors: lachmann n. Stem Cells Dev. 2012 Mar 20;21(5):689-701. doi: 10.1089/scd.2011.0010. Epub 2011 Aug 24. Stem Cells Dev. 2012. PMID: 21732815

3

MicroRNA-150-regulated vectors allow lymphocyte-sparing transgene expression in hematopoietic gene therapy.

Lachmann N, Jagielska J, Heckl D, Brennig S, Pfaff N, Maetzig T, Modlich U, Cantz T, Gentner B, Schambach A, Moritz T. Lachmann N, et al. Gene Ther. 2012 Sep;19(9):915-24. doi: 10.1038/gt.2011.148. Epub 2011 Oct 6. Gene Ther. 2012. PMID: 21975463

4

In vivo enrichment of cytidine deaminase gene-modified hematopoietic cells by prolonged cytosine-arabinoside application.

Brennig S, Rattmann I, Lachmann N, Schambach A, Williams DA, Moritz T. Brennig S, et al. Among authors: lachmann n. Cytotherapy. 2012 Apr;14(4):451-60. doi: 10.3109/14653249.2011.646043. Epub 2012 Jan 16. Cytotherapy. 2012. PMID: 22242831

5

Efficient in vivo regulation of cytidine deaminase expression in the haematopoietic system using a doxycycline-inducible lentiviral vector system.

Lachmann N, Brennig S, Pfaff N, Schermeier H, Dahlmann J, Phaltane R, Gruh I, Modlich U, Schambach A, Baum C, Moritz T. Lachmann N, et al. Gene Ther. 2013 Mar;20(3):298-307. doi: 10.1038/gt.2012.40. Epub 2012 May 17. Gene Ther. 2013. PMID: 22592598

6

A ubiquitous chromatin opening element prevents transgene silencing in pluripotent stem cells and their differentiated progeny.

Pfaff N, Lachmann N, Ackermann M, Kohlscheen S, Brendel C, Maetzig T, Niemann H, Antoniou MN, Grez M, Schambach A, Cantz T, Moritz T. Pfaff N, et al. Among authors: lachmann n. Stem Cells. 2013 Mar;31(3):488-99. doi: 10.1002/stem.1316. Stem Cells. 2013. PMID: 23307570

7

Myeloprotection by cytidine deaminase gene transfer in antileukemic therapy.

Lachmann N, Brennig S, Phaltane R, Flasshove M, Dilloo D, Moritz T. Lachmann N, et al. Neoplasia. 2013 Mar;15(3):239-48. doi: 10.1593/neo.121954. Neoplasia. 2013. PMID: 23479503 Free PMC article. Review.

8

Promoter and lineage independent anti-silencing activity of the A2 ubiquitous chromatin opening element for optimized human pluripotent stem cell-based gene therapy.

Ackermann M, Lachmann N, Hartung S, Eggenschwiler R, Pfaff N, Happle C, Mucci A, Göhring G, Niemann H, Hansen G, Schambach A, Cantz T, Zweigerdt R, Moritz T. Ackermann M, et al. Among authors: lachmann n. Biomaterials. 2014 Feb;35(5):1531-42. doi: 10.1016/j.biomaterials.2013.11.024. Epub 2013 Nov 26. Biomaterials. 2014. PMID: 24290698

9

Lentiviral MGMT(P140K)-mediated in vivo selection employing a ubiquitous chromatin opening element (A2UCOE) linked to a cellular promoter.

Phaltane R, Lachmann N, Brennig S, Ackermann M, Modlich U, Moritz T. Phaltane R, et al. Among authors: lachmann n. Biomaterials. 2014 Aug;35(25):7204-13. doi: 10.1016/j.biomaterials.2014.05.001. Epub 2014 May 27. Biomaterials. 2014. PMID: 24875758

10

Pulmonary transplantation of macrophage progenitors as effective and long-lasting therapy for hereditary pulmonary alveolar proteinosis.

Happle C, Lachmann N, Škuljec J, Wetzke M, Ackermann M, Brennig S, Mucci A, Jirmo AC, Groos S, Mirenska A, Hennig C, Rodt T, Bankstahl JP, Schwerk N, Moritz T, Hansen G. Happle C, et al. Among authors: lachmann n. Sci Transl Med. 2014 Aug 20;6(250):250ra113. doi: 10.1126/scitranslmed.3009750. Sci Transl Med. 2014. PMID: 25143363

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