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Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity.
Lackey DE, Lynch CJ, Olson KC, Mostaedi R, Ali M, Smith WH, Karpe F, Humphreys S, Bedinger DH, Dunn TN, Thomas AP, Oort PJ, Kieffer DA, Amin R, Bettaieb A, Haj FG, Permana P, Anthony TG, Adams SH. Lackey DE, et al. Am J Physiol Endocrinol Metab. 2013 Jun 1;304(11):E1175-87. doi: 10.1152/ajpendo.00630.2012. Epub 2013 Mar 19. Am J Physiol Endocrinol Metab. 2013. PMID: 23512805 Free PMC article.
Regulation of metabolism by the innate immune system.
Lackey DE, Olefsky JM. Lackey DE, et al. Nat Rev Endocrinol. 2016 Jan;12(1):15-28. doi: 10.1038/nrendo.2015.189. Epub 2015 Nov 10. Nat Rev Endocrinol. 2016. PMID: 26553134 Review.
The role of dietary fat in obesity-induced insulin resistance.
Lackey DE, Lazaro RG, Li P, Johnson A, Hernandez-Carretero A, Weber N, Vorobyova I, Tsukomoto H, Osborn O. Lackey DE, et al. Am J Physiol Endocrinol Metab. 2016 Dec 1;311(6):E989-E997. doi: 10.1152/ajpendo.00323.2016. Epub 2016 Nov 1. Am J Physiol Endocrinol Metab. 2016. PMID: 27802965 Free PMC article.
A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice.
Oh DY, Walenta E, Akiyama TE, Lagakos WS, Lackey D, Pessentheiner AR, Sasik R, Hah N, Chi TJ, Cox JM, Powels MA, Di Salvo J, Sinz C, Watkins SM, Armando AM, Chung H, Evans RM, Quehenberger O, McNelis J, Bogner-Strauss JG, Olefsky JM. Oh DY, et al. Nat Med. 2014 Aug;20(8):942-7. doi: 10.1038/nm.3614. Epub 2014 Jul 6. Nat Med. 2014. PMID: 24997608 Free PMC article.
Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer.
Suh JM, Jonker JW, Ahmadian M, Goetz R, Lackey D, Osborn O, Huang Z, Liu W, Yoshihara E, van Dijk TH, Havinga R, Fan W, Yin YQ, Yu RT, Liddle C, Atkins AR, Olefsky JM, Mohammadi M, Downes M, Evans RM. Suh JM, et al. Nature. 2014 Sep 18;513(7518):436-9. doi: 10.1038/nature13540. Epub 2014 Jul 16. Nature. 2014. PMID: 25043058 Free PMC article.
Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance.
Fang S, Suh JM, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, Coulter S, Liddle C, Schoonjans K, Olefsky JM, Saltiel AR, Downes M, Evans RM. Fang S, et al. Nat Med. 2015 Feb;21(2):159-65. doi: 10.1038/nm.3760. Epub 2015 Jan 5. Nat Med. 2015. PMID: 25559344 Free PMC article.
16 results