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410 results

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Page 1
Lactobacillus acidophilus ameliorates cholestatic liver injury through inhibiting bile acid synthesis and promoting bile acid excretion.
Wu L, Zhou J, Zhou A, Lei Y, Tang L, Hu S, Wang S, Xiao X, Chen Q, Tu D, Lu C, Lai Y, Li Y, Zhang X, Tang B, Yang S. Wu L, et al. Gut Microbes. 2024 Jan-Dec;16(1):2390176. doi: 10.1080/19490976.2024.2390176. Epub 2024 Aug 29. Gut Microbes. 2024. PMID: 39205654 Free PMC article. Clinical Trial.
The purpose of this study was to examine the effects and mechanisms of Lactobacillus acidophilus (L. acidophilus) on cholestatic liver injury in both animals and humans. ...BDL induced different severity of liver injury, which was associated with gut micro …
The purpose of this study was to examine the effects and mechanisms of Lactobacillus acidophilus (L. acidophilus) on ch …
Probiotic significance of Lactobacillus strains: a comprehensive review on health impacts, research gaps, and future prospects.
Shah AB, Baiseitova A, Zahoor M, Ahmad I, Ikram M, Bakhsh A, Shah MA, Ali I, Idress M, Ullah R, Nasr FA, Al-Zharani M. Shah AB, et al. Gut Microbes. 2024 Jan-Dec;16(1):2431643. doi: 10.1080/19490976.2024.2431643. Epub 2024 Nov 24. Gut Microbes. 2024. PMID: 39582101 Free PMC article. Review.
The gastrointestinal and urinary tracts are home to these bacteria, which play a vital role in the microbial flora of both humans and animals. The Lactobacillus probiotic, i.e, Lactobacillus plantarum, Lactobacillus paracasei, Lactobacillus acidophi …
The gastrointestinal and urinary tracts are home to these bacteria, which play a vital role in the microbial flora of both humans and animal …
Lactobacillus acidophilus promotes cognitive function recovery via regulating microglial peroxisomal function in cerebral ischemia.
Huang Y, Zhang X, Yu C, Liu Y, Kang H, Liu Y, Ni Y, Xia Y, Jiang Z, Chen J, Zhao K, Han L, Zou X, Wang J, Lei T, Gan C, Zhang H. Huang Y, et al. Cell Host Microbe. 2025 Sep 10;33(9):1484-1501.e12. doi: 10.1016/j.chom.2025.07.018. Epub 2025 Aug 13. Cell Host Microbe. 2025. PMID: 40812303
Our metagenomics linked low Lactobacillus abundance to cognitive decline in patients with cerebral ischemia. L. acidophilus supplementation alleviated post-ischemic deficits in murine middle cerebral artery occlusion and bilateral carotid artery stenosis models. ... …
Our metagenomics linked low Lactobacillus abundance to cognitive decline in patients with cerebral ischemia. L. acidophilus su …
Lactobacillus acidophilus DDS-1 and Bifidobacterium lactis UABla-12 Improve Abdominal Pain Severity and Symptomology in Irritable Bowel Syndrome: Randomized Controlled Trial.
Martoni CJ, Srivastava S, Leyer GJ. Martoni CJ, et al. Nutrients. 2020 Jan 30;12(2):363. doi: 10.3390/nu12020363. Nutrients. 2020. PMID: 32019158 Free PMC article. Clinical Trial.
Three hundred and thirty adults, aged 18 to 70 years, with IBS according to Rome IV criteria were allocated (1:1:1) to receive placebo, Lactobacillus acidophilus DDS-1 (1 10(10) CFU/day) or Bifidobacterium animalis subsp. lactis UABla-12 (1 10(10) CFU/day) over …
Three hundred and thirty adults, aged 18 to 70 years, with IBS according to Rome IV criteria were allocated (1:1:1) to receive placebo, L …
Bifidobacterium and Lactobacillus Probiotics and Gut Dysbiosis in Preterm Infants: The PRIMAL Randomized Clinical Trial.
Van Rossum T, Haiß A, Knoll RL, Marißen J, Podlesny D, Pagel J, Bleskina M, Vens M, Fortmann I, Siller B, Ricklefs I, Klopp J, Hilbert K, Meyer C, Thielemann R, Goedicke-Fritz S, Kuntz M, Wieg C, Teig N, Körner T, Kribs A, Hudalla H, Knuf M, Stein A, Gille C, Bagci S, Dohle F, Proquitté H, Olbertz DM, Schmidt E, Koch L, Pirr S, Rupp J, Spiegler J, Kopp MV, Göpel W, Herting E, Forslund SK, Viemann D, Zemlin M, Bork P, Gehring S, König IR, Henneke P, Härtel C. Van Rossum T, et al. JAMA Pediatr. 2024 Oct 1;178(10):985-995. doi: 10.1001/jamapediatrics.2024.2626. JAMA Pediatr. 2024. PMID: 39102225 Free PMC article. Clinical Trial.
IMPORTANCE: The effects of probiotic interventions on colonization with resistant bacteria and early microbiome development in preterm infants remain to be clarified. OBJECTIVE: To examine the efficacy of Bifidobacterium longum subsp infantis, Bifidobacterium animalis subs …
IMPORTANCE: The effects of probiotic interventions on colonization with resistant bacteria and early microbiome development in preter …
Lactobacillus acidophilus potentiates oncolytic virotherapy through modulating gut microbiota homeostasis in hepatocellular carcinoma.
Zhang J, Yang J, Luo J, Wu W, Luo H, Wei W, Lyu H, Wang Y, Yi H, Zhang Y, Fan Z, Lyu H, Kanakaveti VP, Qin B, Yuan P, Yang R, Zhang H, Zuo T, Felsher DW, Lee MH, Li K. Zhang J, et al. Nat Commun. 2025 Apr 7;16(1):3315. doi: 10.1038/s41467-025-58407-z. Nat Commun. 2025. PMID: 40195307 Free PMC article.
VSVdelta51 reduced intestinal expression of SLC20A1 that binds to Lactobacillus acidophilus (L. acidophilus) CdpA cell wall protein through IL6-JAK-STAT3 signaling, thereby attenuating attachment and colonization of L. acidophilus. L. acidophilus …
VSVdelta51 reduced intestinal expression of SLC20A1 that binds to Lactobacillus acidophilus (L. acidophilus) CdpA cell …
Lactobacillus acidophilus extracellular vesicles-coated UiO-66-NH(2)@siRNA nanoparticles for ulcerative colitis targeted gene therapy and gut microbiota modulation.
Cui C, Tang J, Chen J, Zhang B, Li R, Zhang Q, Qiu C, Chen R, Min G, Sun Z, Weng H. Cui C, et al. J Nanobiotechnology. 2025 Apr 17;23(1):301. doi: 10.1186/s12951-025-03376-0. J Nanobiotechnology. 2025. PMID: 40247297 Free PMC article.
Here, we have designed an innovative integrated therapeutic strategy using Lactobacillus acidophilus extracellular vesicles (EVs) to encapsulate UiO-66-NH(2) nanoparticles bounded with TNF-alpha siRNA (EVs@UiO-66-NH(2)@siRNA) for UC treatment. This system shows supe …
Here, we have designed an innovative integrated therapeutic strategy using Lactobacillus acidophilus extracellular vesicles (E …
Gut microbiome Lactobacillus acidophilus and its relationship with thyroid nodules and thyroid hormonal profile.
Mohamed Mojahed Eladly MAE, Morsy HE, Elnabrawy IMS, Hendawy LMA, Abd ElHady AMM. Mohamed Mojahed Eladly MAE, et al. Endokrynol Pol. 2025;76(5):499-506. doi: 10.5603/ep.105734. Endokrynol Pol. 2025. PMID: 41069145 Free article.
However, there is no proven link between the gut microbiota and thyroid nodules. Researchers will examine the correlation between Lactobacillus acidophilus and thyroid nodules and hormones. ...There was highly significant variation between the studied groups. …
However, there is no proven link between the gut microbiota and thyroid nodules. Researchers will examine the correlation between …
Dietary modulation of gut microbiota affects susceptibility to drug-induced liver injury.
Pan H, Song D, Wang Z, Yang X, Luo P, Li W, Li Y, Gong M, Zhang C. Pan H, et al. Gut Microbes. 2024 Jan-Dec;16(1):2439534. doi: 10.1080/19490976.2024.2439534. Epub 2024 Dec 14. Gut Microbes. 2024. PMID: 39673542 Free PMC article.
Gut microbiota transplantation further confirms these differing outcomes are mediated by diet-induced variations in gut microbiota. Mechanistically, Lactobacillus acidophilus, enriched by HFiD, alleviates DILI through its metabolite indole-3-lactic aci …
Gut microbiota transplantation further confirms these differing outcomes are mediated by diet-induced variations in gut microbiota …
Choosing an appropriate probiotic product for your patient: An evidence-based practical guide.
Sniffen JC, McFarland LV, Evans CT, Goldstein EJC. Sniffen JC, et al. PLoS One. 2018 Dec 26;13(12):e0209205. doi: 10.1371/journal.pone.0209205. eCollection 2018. PLoS One. 2018. PMID: 30586435 Free PMC article.
For example, several types of probiotics had strong evidence for the prevention of antibiotic-associated diarrhea [Saccharomyces boulardii I-745, a three-strain mixture (Lactobacillus acidophilus CL1285, L. casei Lbc80r, L. rhamnosus CLR2) and L. casei DN114001]. .. …
For example, several types of probiotics had strong evidence for the prevention of antibiotic-associated diarrhea [Saccharomyces boulardii I …
410 results