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Crohn's disease patients carrying Nod2/CARD15 gene variants have an increased and early need for first surgery due to stricturing disease and higher rate of surgical recurrence.
Alvarez-Lobos M, Arostegui JI, Sans M, Tassies D, Plaza S, Delgado S, Lacy AM, Pique JM, Yagüe J, Panés J. Alvarez-Lobos M, et al. Among authors: lacy am. Ann Surg. 2005 Nov;242(5):693-700. doi: 10.1097/01.sla.0000186173.14696.ea. Ann Surg. 2005. PMID: 16244543 Free PMC article.
Postoperative surveillance in patients with colorectal cancer who have undergone curative resection: a prospective, multicenter, randomized, controlled trial.
Rodríguez-Moranta F, Saló J, Arcusa A, Boadas J, Piñol V, Bessa X, Batiste-Alentorn E, Lacy AM, Delgado S, Maurel J, Piqué JM, Castells A. Rodríguez-Moranta F, et al. Among authors: lacy am. J Clin Oncol. 2006 Jan 20;24(3):386-93. doi: 10.1200/JCO.2005.02.0826. Epub 2005 Dec 19. J Clin Oncol. 2006. PMID: 16365182 Clinical Trial.
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