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Human L-ficolin recognizes phosphocholine moieties of pneumococcal teichoic acid.
Vassal-Stermann E, Lacroix M, Gout E, Laffly E, Pedersen CM, Martin L, Amoroso A, Schmidt RR, Zähringer U, Gaboriaud C, Di Guilmi AM, Thielens NM. Vassal-Stermann E, et al. Among authors: laffly e. J Immunol. 2014 Dec 1;193(11):5699-708. doi: 10.4049/jimmunol.1400127. Epub 2014 Oct 24. J Immunol. 2014. PMID: 25344472 Free article.
[Monoclonal antibodies, 30 years of success].
Laffly E, Sodoyer R. Laffly E, et al. J Soc Biol. 2006;200(4):325-43. doi: 10.1051/jbio:2006037. J Soc Biol. 2006. PMID: 17652969 Review. French.
Selection of a macaque Fab with framework regions like those in humans, high affinity, and ability to neutralize the protective antigen (PA) of Bacillus anthracis by binding to the segment of PA between residues 686 and 694.
Laffly E, Danjou L, Condemine F, Vidal D, Drouet E, Lefranc MP, Bottex C, Thullier P. Laffly E, et al. Antimicrob Agents Chemother. 2005 Aug;49(8):3414-20. doi: 10.1128/AAC.49.8.3414-3420.2005. Antimicrob Agents Chemother. 2005. PMID: 16048955 Free PMC article.
High-affinity, human antibody-like antibody fragment (single-chain variable fragment) neutralizing the lethal factor (LF) of Bacillus anthracis by inhibiting protective antigen-LF complex formation.
Pelat T, Hust M, Laffly E, Condemine F, Bottex C, Vidal D, Lefranc MP, Dübel S, Thullier P. Pelat T, et al. Among authors: laffly e. Antimicrob Agents Chemother. 2007 Aug;51(8):2758-64. doi: 10.1128/AAC.01528-06. Epub 2007 May 21. Antimicrob Agents Chemother. 2007. PMID: 17517846 Free PMC article.