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Differential inhibition of long-chain acyl-CoA hydrolases by hypolipidemic drugs in vitro.
Sánchez RM, Alegret M, Adzet T, Merlos M, Laguna JC. Sánchez RM, et al. Among authors: laguna jc. Biochem Pharmacol. 1992 Feb 4;43(3):639-44. doi: 10.1016/0006-2952(92)90589-b. Biochem Pharmacol. 1992. PMID: 1347213
Different response of senescent female Sprague-Dawley rats to gemfibrozil and rosiglitazone administration.
Sanguino E, Roglans N, Alegret M, Sánchez RM, Vázquez-Carrera M, Laguna JC. Sanguino E, et al. Among authors: laguna jc. Exp Gerontol. 2005 Jul;40(7):588-98. doi: 10.1016/j.exger.2005.05.006. Exp Gerontol. 2005. PMID: 15998575
Gemfibrozil increases the specific binding of rat-cortex nuclear extracts to a PPRE probe.
Sanguino E, Ramón M, Roglans N, Alegret M, Sánchez RM, Vázquez-Carrera M, Laguna JC. Sanguino E, et al. Among authors: laguna jc. Life Sci. 2003 Oct 24;73(23):2927-37. doi: 10.1016/j.lfs.2003.04.001. Life Sci. 2003. PMID: 14519442
Down-regulation of acyl-CoA oxidase gene expression in heart of troglitazone-treated mice through a mechanism involving chicken ovalbumin upstream promoter transcription factor II.
Cabrero A, Jové M, Planavila A, Merlos M, Laguna JC, Vázquez-Carrera M. Cabrero A, et al. Among authors: laguna jc. Mol Pharmacol. 2003 Sep;64(3):764-72. doi: 10.1124/mol.64.3.764. Mol Pharmacol. 2003. PMID: 12920214
Effects of rosiglitazone and atorvastatin on the expression of genes that control cholesterol homeostasis in differentiating monocytes.
Llaverias G, Rebollo A, Pou J, Vázquez-Carrera M, Sánchez RM, Laguna JC, Alegret M. Llaverias G, et al. Among authors: laguna jc. Biochem Pharmacol. 2006 Feb 28;71(5):605-14. doi: 10.1016/j.bcp.2005.11.022. Epub 2006 Jan 18. Biochem Pharmacol. 2006. PMID: 16386711
Atorvastatin reverses age-related reduction in rat hepatic PPARalpha and HNF-4.
Sanguino E, Roglans N, Alegret M, Sánchez RM, Vázquez-Carrera M, Laguna JC. Sanguino E, et al. Among authors: laguna jc. Br J Pharmacol. 2005 Aug;145(7):853-61. doi: 10.1038/sj.bjp.0706260. Br J Pharmacol. 2005. PMID: 15912134 Free PMC article.
Prevention of age-related changes in rat cortex transcription factor activator protein-1 by hypolipidemic drugs.
Sanguino E, Roglans N, Alegret M, Sánchez RM, Vázquez-Carrera M, Laguna JC. Sanguino E, et al. Among authors: laguna jc. Biochem Pharmacol. 2004 Oct 1;68(7):1411-21. doi: 10.1016/j.bcp.2004.06.008. Biochem Pharmacol. 2004. PMID: 15345331
Reduction of intracellular cholesterol accumulation in THP-1 macrophages by a combination of rosiglitazone and atorvastatin.
Llaverias G, Lacasa D, Viñals M, Vázquez-Carrera M, Sánchez RM, Laguna JC, Alegret M. Llaverias G, et al. Among authors: laguna jc. Biochem Pharmacol. 2004 Jul 1;68(1):155-63. doi: 10.1016/j.bcp.2004.03.009. Biochem Pharmacol. 2004. PMID: 15183127
Fibrates modify the expression of key factors involved in bile-acid synthesis and biliary-lipid secretion in gallstone patients.
Roglans N, Vázquez-Carrera M, Alegret M, Novell F, Zambón D, Ros E, Laguna JC, Sánchez RM. Roglans N, et al. Among authors: laguna jc. Eur J Clin Pharmacol. 2004 Feb;59(12):855-61. doi: 10.1007/s00228-003-0704-1. Epub 2003 Dec 18. Eur J Clin Pharmacol. 2004. PMID: 14685799 Clinical Trial.
Lack of hypotriglyceridemic effect of gemfibrozil as a consequence of age-related changes in rat liver PPARalpha.
Sanguino E, Ramón M, Michalik L, Wahli W, Alegret M, Sánchez RM, Vázquez-Carrera M, Laguna JC. Sanguino E, et al. Among authors: laguna jc. Biochem Pharmacol. 2004 Jan 1;67(1):157-66. doi: 10.1016/j.bcp.2003.08.034. Biochem Pharmacol. 2004. PMID: 14667938
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