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Local gene therapy durably restores vestibular function in a mouse model of Usher syndrome type 1G.
Emptoz A, Michel V, Lelli A, Akil O, Boutet de Monvel J, Lahlou G, Meyer A, Dupont T, Nouaille S, Ey E, Franca de Barros F, Beraneck M, Dulon D, Hardelin JP, Lustig L, Avan P, Petit C, Safieddine S. Emptoz A, et al. Among authors: lahlou g. Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):9695-9700. doi: 10.1073/pnas.1708894114. Epub 2017 Aug 23. Proc Natl Acad Sci U S A. 2017. PMID: 28835534 Free PMC article.
[Gene therapy progress: hopes for Usher syndrome].
Calvet C, Lahlou G, Safieddine S. Calvet C, et al. Among authors: lahlou g. Med Sci (Paris). 2018 Oct;34(10):842-848. doi: 10.1051/medsci/2018210. Epub 2018 Nov 19. Med Sci (Paris). 2018. PMID: 30451679 Free article. Review. French.
Dual AAV-mediated gene therapy restores hearing in a DFNB9 mouse model.
Akil O, Dyka F, Calvet C, Emptoz A, Lahlou G, Nouaille S, Boutet de Monvel J, Hardelin JP, Hauswirth WW, Avan P, Petit C, Safieddine S, Lustig LR. Akil O, et al. Among authors: lahlou g. Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4496-4501. doi: 10.1073/pnas.1817537116. Epub 2019 Feb 19. Proc Natl Acad Sci U S A. 2019. PMID: 30782832 Free PMC article.
The SNARE protein SNAP-25 is required for normal exocytosis at auditory hair cell ribbon synapses.
Calvet C, Peineau T, Benamer N, Cornille M, Lelli A, Plion B, Lahlou G, Fanchette J, Nouaille S, Boutet de Monvel J, Estivalet A, Jean P, Michel V, Sachse M, Michalski N, Avan P, Petit C, Dulon D, Safieddine S. Calvet C, et al. Among authors: lahlou g. iScience. 2022 Nov 22;25(12):105628. doi: 10.1016/j.isci.2022.105628. eCollection 2022 Dec 22. iScience. 2022. PMID: 36483015 Free PMC article.
57 results