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Environmental control of invasin expression in Yersinia pseudotuberculosis is mediated by regulation of RovA, a transcriptional activator of the SlyA/Hor family.
Nagel G, Lahrz A, Dersch P. Nagel G, et al. Mol Microbiol. 2001 Sep;41(6):1249-69. doi: 10.1046/j.1365-2958.2001.02522.x. Mol Microbiol. 2001. PMID: 11580832
We investigated invasin expression and found that the inv gene is regulated in response to a variety of environmental signals, such as temperature, growth phase, nutrients, osmolarity and pH, and requires the product of rovA, a member of the SlyA/Hor transcriptional …
We investigated invasin expression and found that the inv gene is regulated in response to a variety of environmental signals, such a …
The calcineurin inhibitor gossypol impairs growth, cell signalling and development in Dictyostelium discoideum.
Weissenmayer B, Boeckeler K, Lahrz A, Mutzel R. Weissenmayer B, et al. FEMS Microbiol Lett. 2005 Jan 1;242(1):19-25. doi: 10.1016/j.femsle.2004.10.035. FEMS Microbiol Lett. 2005. PMID: 15621416
A cell line that overproduces the catalytic subunit of calcineurin was more resistant to gossypol....
A cell line that overproduces the catalytic subunit of calcineurin was more resistant to gossypol....
Endothelin-1-mediated Drug Resistance in EGFR-mutant NSCLC.
Pulido I, Ollosi S, Aparisi S, Becker JH, Aliena-Valero A, Benet M, Rodríguez ML, López A, Tamayo-Torres E, Chuliá-Peris L, García-Cañaveras JC, Soucheray M, Dalheim AV, Salom JB, Qiu W, Kaja S, Alcácer Fernández-Coronado J, Alandes S, Alcácer J, Al-Shahrour F, Borgia JA, Juan O, Nishimura MI, Lahoz A, Carretero J, Shimamura T. Pulido I, et al. Among authors: lahoz a. Cancer Res. 2020 Aug 3:canres.0141.2020. doi: 10.1158/0008-5472.CAN-20-0141. Online ahead of print. Cancer Res. 2020. PMID: 32747363
Methods for analysis of specific DNA methylation status.
Pajares MJ, Palanca-Ballester C, Urtasun R, Alemany-Cosme E, Lahoz A, Sandoval J. Pajares MJ, et al. Among authors: lahoz a. Methods. 2020 Jul 5:S1046-2023(20)30097-9. doi: 10.1016/j.ymeth.2020.06.021. Online ahead of print. Methods. 2020. PMID: 32640317 Review.
A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway.
Ghergurovich JM, García-Cañaveras JC, Wang J, Schmidt E, Zhang Z, TeSlaa T, Patel H, Chen L, Britt EC, Piqueras-Nebot M, Gomez-Cabrera MC, Lahoz A, Fan J, Beier UH, Kim H, Rabinowitz JD. Ghergurovich JM, et al. Among authors: lahoz a. Nat Chem Biol. 2020 Jul;16(7):731-739. doi: 10.1038/s41589-020-0533-x. Epub 2020 May 11. Nat Chem Biol. 2020. PMID: 32393898
Glutamine/glutamate metabolism rewiring in reprogrammed human hepatocyte-like cells.
Ballester M, Sentandreu E, Luongo G, Santamaria R, Bolonio M, Alcoriza-Balaguer MI, Palomino-Schätzlein M, Pineda-Lucena A, Castell J, Lahoz A, Bort R. Ballester M, et al. Among authors: lahoz a. Sci Rep. 2019 Nov 29;9(1):17978. doi: 10.1038/s41598-019-54357-x. Sci Rep. 2019. PMID: 31784643 Free PMC article.
Identification of a novel synthetic lethal vulnerability in non-small cell lung cancer by co-targeting TMPRSS4 and DDR1.
Villalba M, Redin E, Exposito F, Pajares MJ, Sainz C, Hervas D, Guruceaga E, Diaz-Lagares A, Cirauqui C, Redrado M, Valencia K, de Andrea C, Jantus-Lewintre E, Camps C, Lopez-Lopez R, Lahoz A, Montuenga L, Pio R, Sandoval J, Calvo A. Villalba M, et al. Among authors: lahoz a. Sci Rep. 2019 Oct 28;9(1):15400. doi: 10.1038/s41598-019-51066-3. Sci Rep. 2019. PMID: 31659178 Free PMC article.
Prediagnostic Plasma Bile Acid Levels and Colon Cancer Risk: A Prospective Study.
Kühn T, Stepien M, López-Nogueroles M, Damms-Machado A, Sookthai D, Johnson T, Roca M, Hüsing A, Maldonado SG, Cross AJ, Murphy N, Freisling H, Rinaldi S, Scalbert A, Fedirko V, Severi G, Boutron-Ruault MC, Mancini FR, Sowah SA, Boeing H, Jakszyn P, Sánchez MJ, Merino S, Colorado-Yohar S, Barricarte A, Khaw KT, Schmidt JA, Perez-Cornago A, Trichopoulou A, Karakatsani A, Thriskos P, Palli D, Agnoli C, Tumino R, Sacerdote C, Panico S, Bueno-de-Mesquita B, van Gils CH, Heath AK, Gunter MJ, Riboli E, Lahoz A, Jenab M, Kaaks R. Kühn T, et al. Among authors: lahoz a. J Natl Cancer Inst. 2020 May 1;112(5):516-524. doi: 10.1093/jnci/djz166. J Natl Cancer Inst. 2020. PMID: 31435679 Free PMC article.
CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC.
Becker JH, Gao Y, Soucheray M, Pulido I, Kikuchi E, Rodríguez ML, Gandhi R, Lafuente-Sanchis A, Aupí M, Alcácer Fernández-Coronado J, Martín-Martorell P, Cremades A, Galbis-Caravajal JM, Alcácer J, Christensen CL, Simms P, Hess A, Asahina H, Kahle MP, Al-Shahrour F, Borgia JA, Lahoz A, Insa A, Juan O, Jänne PA, Wong KK, Carretero J, Shimamura T. Becker JH, et al. Among authors: lahoz a. Cancer Res. 2019 Sep 1;79(17):4439-4452. doi: 10.1158/0008-5472.CAN-19-0024. Epub 2019 Jul 4. Cancer Res. 2019. PMID: 31273063 Free PMC article.
LipidMS: An R Package for Lipid Annotation in Untargeted Liquid Chromatography-Data Independent Acquisition-Mass Spectrometry Lipidomics.
Alcoriza-Balaguer MI, García-Cañaveras JC, López A, Conde I, Juan O, Carretero J, Lahoz A. Alcoriza-Balaguer MI, et al. Among authors: lahoz a. Anal Chem. 2019 Jan 2;91(1):836-845. doi: 10.1021/acs.analchem.8b03409. Epub 2018 Dec 13. Anal Chem. 2019. PMID: 30500173
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