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Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5.
Clark KL, Halay ED, Lai E, Burley SK. Clark KL, et al. Among authors: lai e. Nature. 1993 Jul 29;364(6436):412-20. doi: 10.1038/364412a0. Nature. 1993. PMID: 8332212
The cell-specific enhancer of the mouse transthyretin (prealbumin) gene binds a common factor at one site and a liver-specific factor(s) at two other sites.
Costa RH, Lai E, Grayson DR, Darnell JE Jr. Costa RH, et al. Among authors: lai e. Mol Cell Biol. 1988 Jan;8(1):81-90. doi: 10.1128/mcb.8.1.81. Mol Cell Biol. 1988. PMID: 3336368 Free PMC article.
Costa, E. Lai, and J. E. Darnell, Jr., Mol. Cell. Biol. 6:4697-4708, 1986). In this report, we located the effective transthyretin enhancer element within a 100-bp region between 1.96 and 1.86 kb 5' to the mRNA cap site. ...
Costa, E. Lai, and J. E. Darnell, Jr., Mol. Cell. Biol. 6:4697-4708, 1986). In this report, we located the effective tr …
Hepatocyte nuclear factor 3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic function.
Lai E, Clark KL, Burley SK, Darnell JE Jr. Lai E, et al. Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10421-3. doi: 10.1073/pnas.90.22.10421. Proc Natl Acad Sci U S A. 1993. PMID: 8248124 Free PMC article.
Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily.
Sladek FM, Zhong WM, Lai E, Darnell JE Jr. Sladek FM, et al. Among authors: lai e. Genes Dev. 1990 Dec;4(12B):2353-65. doi: 10.1101/gad.4.12b.2353. Genes Dev. 1990. PMID: 2279702
HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally.
Lai E, Prezioso VR, Smith E, Litvin O, Costa RH, Darnell JE Jr. Lai E, et al. Genes Dev. 1990 Aug;4(8):1427-36. doi: 10.1101/gad.4.8.1427. Genes Dev. 1990. PMID: 2227418
Differential regulation of hepatocyte-enriched transcription factors explains changes in albumin and transthyretin gene expression among hepatoma cells.
Herbst RS, Nielsch U, Sladek F, Lai E, Babiss LE, Darnell JE Jr. Herbst RS, et al. Among authors: lai e. New Biol. 1991 Mar;3(3):289-96. New Biol. 1991. PMID: 1878351
Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head.
Lai E, Prezioso VR, Tao WF, Chen WS, Darnell JE Jr. Lai E, et al. Genes Dev. 1991 Mar;5(3):416-27. doi: 10.1101/gad.5.3.416. Genes Dev. 1991. PMID: 1672118
Hepatocyte nuclear factor 3 beta contains two transcriptional activation domains, one of which is novel and conserved with the Drosophila fork head protein.
Pani L, Overdier DG, Porcella A, Qian X, Lai E, Costa RH. Pani L, et al. Among authors: lai e. Mol Cell Biol. 1992 Sep;12(9):3723-32. doi: 10.1128/mcb.12.9.3723. Mol Cell Biol. 1992. PMID: 1324404 Free PMC article.
Telencephalon-restricted expression of BF-1, a new member of the HNF-3/fork head gene family, in the developing rat brain.
Tao W, Lai E. Tao W, et al. Among authors: lai e. Neuron. 1992 May;8(5):957-66. doi: 10.1016/0896-6273(92)90210-5. Neuron. 1992. PMID: 1350202
FAST-2 is a mammalian winged-helix protein which mediates transforming growth factor beta signals.
Liu B, Dou CL, Prabhu L, Lai E. Liu B, et al. Among authors: lai e. Mol Cell Biol. 1999 Jan;19(1):424-30. doi: 10.1128/mcb.19.1.424. Mol Cell Biol. 1999. PMID: 9858566 Free PMC article.
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