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NK cell receptor and ligand composition influences the clearance of SARS-CoV-2.
Hsieh WC, Lai EY, Liu YT, Wang YF, Tzeng YS, Cui L, Lai YJ, Huang HC, Huang JH, Ni HC, Tsai DY, Liang JJ, Liao CC, Lu YT, Jiang L, Liu MT, Wang JT, Chang SY, Chen CY, Tsai HC, Chang YM, Wernig G, Li CW, Lin KI, Lin YL, Tsai HK, Huang YT, Chen SY. Hsieh WC, et al. Among authors: lai ey, lai yj. J Clin Invest. 2021 Nov 1;131(21):e146408. doi: 10.1172/JCI146408. J Clin Invest. 2021. PMID: 34720095 Free PMC article.
IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion.
Chan LC, Li CW, Xia W, Hsu JM, Lee HH, Cha JH, Wang HL, Yang WH, Yen EY, Chang WC, Zha Z, Lim SO, Lai YJ, Liu C, Liu J, Dong Q, Yang Y, Sun L, Wei Y, Nie L, Hsu JL, Li H, Ye Q, Hassan MM, Amin HM, Kaseb AO, Lin X, Wang SC, Hung MC. Chan LC, et al. Among authors: lai yj. J Clin Invest. 2019 Jul 15;129(8):3324-3338. doi: 10.1172/JCI126022. eCollection 2019 Jul 15. J Clin Invest. 2019. PMID: 31305264 Free PMC article.
Targeting Glycosylated PD-1 Induces Potent Antitumor Immunity.
Sun L, Li CW, Chung EM, Yang R, Kim YS, Park AH, Lai YJ, Yang Y, Wang YH, Liu J, Qiu Y, Khoo KH, Yao J, Hsu JL, Cha JH, Chan LC, Hsu JM, Lee HH, Yoo SS, Hung MC. Sun L, et al. Among authors: lai yj. Cancer Res. 2020 Jun 1;80(11):2298-2310. doi: 10.1158/0008-5472.CAN-19-3133. Epub 2020 Mar 10. Cancer Res. 2020. PMID: 32156778 Free PMC article.
Rapid generation of mouse model for emerging infectious disease with the case of severe COVID-19.
Sun CP, Jan JT, Wang IH, Ma HH, Ko HY, Wu PY, Kuo TJ, Liao HN, Lan YH, Sie ZL, Chen YH, Ko YA, Liao CC, Chen LY, Lee IJ, Tsung SI, Lai YJ, Chiang MT, Liang JJ, Liu WC, Wang JR, Yuan JP, Lin YS, Tsai YC, Hsieh SL, Li CW, Wu HC, Ko TM, Lin YL, Tao MH. Sun CP, et al. Among authors: lai yj. PLoS Pathog. 2021 Aug 11;17(8):e1009758. doi: 10.1371/journal.ppat.1009758. eCollection 2021 Aug. PLoS Pathog. 2021. PMID: 34379705 Free PMC article.
Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro.
Huang HC, Lai YJ, Liao CC, Yang WF, Huang KB, Lee IJ, Chou WC, Wang SH, Wang LH, Hsu JM, Sun CP, Kuo CT, Wang J, Hsiao TC, Yang PJ, Lee TA, Huang W, Li FA, Shen CY, Lin YL, Tao MH, Li CW. Huang HC, et al. Among authors: lai yj. EBioMedicine. 2021 Dec;74:103712. doi: 10.1016/j.ebiom.2021.103712. Epub 2021 Nov 25. EBioMedicine. 2021. PMID: 34839261 Free PMC article.
Upregulation of PD-L1 by SARS-CoV-2 promotes immune evasion.
Huang HC, Wang SH, Fang GC, Chou WC, Liao CC, Sun CP, Jan JT, Ma HH, Ko HY, Ko YA, Chiang MT, Liang JJ, Kuo CT, Lee TA, Morales-Scheihing D, Shen CY, Chen SY, McCullough LD, Cui L, Wernig G, Tao MH, Lin YL, Chang YM, Wang SP, Lai YJ, Li CW. Huang HC, et al. Among authors: lai yj. J Med Virol. 2023 Feb;95(2):e28478. doi: 10.1002/jmv.28478. J Med Virol. 2023. PMID: 36609964 Free PMC article.
394 results