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A preclinical study on the efficacy and safety of a new vaccine against Coxsackievirus B1 reveals no risk for accelerated diabetes development in mouse models.
Larsson PG, Lakshmikanth T, Laitinen OH, Utorova R, Jacobson S, Oikarinen M, Domsgen E, Koivunen MR, Chaux P, Devard N, Lecouturier V, Almond J, Knip M, Hyöty H, Flodström-Tullberg M. Larsson PG, et al. Among authors: laitinen oh. Diabetologia. 2015 Feb;58(2):346-54. doi: 10.1007/s00125-014-3436-0. Epub 2014 Nov 5. Diabetologia. 2015. PMID: 25370797
A Link Between a Common Mutation in CFTR and Impaired Innate and Adaptive Viral Defense.
Svedin E, Utorova R, Hühn MH, Larsson PG, Stone VM, Garimella M, Lind K, Hägglöf T, Pincikova T, Laitinen OH, McInerney GM, Scholte B, Hjelte L, Karlsson MCI, Flodström-Tullberg M. Svedin E, et al. Among authors: laitinen oh. J Infect Dis. 2017 Dec 5;216(10):1308-1317. doi: 10.1093/infdis/jix474. J Infect Dis. 2017. PMID: 28968805 Free PMC article.
Formalin treatment increases the stability and immunogenicity of coxsackievirus B1 VLP vaccine.
Hankaniemi MM, Stone VM, Andrejeff T, Heinimäki S, Sioofy-Khojine AB, Marjomäki V, Hyöty H, Blazevic V, Flodström-Tullberg M, Hytönen VP, Laitinen OH. Hankaniemi MM, et al. Among authors: laitinen oh. Antiviral Res. 2019 Nov;171:104595. doi: 10.1016/j.antiviral.2019.104595. Epub 2019 Sep 3. Antiviral Res. 2019. PMID: 31491431 Free article.
A hexavalent Coxsackievirus B vaccine is highly immunogenic and has a strong protective capacity in mice and nonhuman primates.
Stone VM, Hankaniemi MM, Laitinen OH, Sioofy-Khojine AB, Lin A, Diaz Lozano IM, Mazur MA, Marjomäki V, Loré K, Hyöty H, Hytönen VP, Flodström-Tullberg M. Stone VM, et al. Among authors: laitinen oh. Sci Adv. 2020 May 6;6(19):eaaz2433. doi: 10.1126/sciadv.aaz2433. eCollection 2020 May. Sci Adv. 2020. PMID: 32494709 Free PMC article.
88 results