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Coxsackievirus B1 infections are associated with the initiation of insulin-driven autoimmunity that progresses to type 1 diabetes.
Sioofy-Khojine AB, Lehtonen J, Nurminen N, Laitinen OH, Oikarinen S, Huhtala H, Pakkanen O, Ruokoranta T, Hankaniemi MM, Toppari J, Vähä-Mäkilä M, Ilonen J, Veijola R, Knip M, Hyöty H. Sioofy-Khojine AB, et al. Among authors: laitinen oh. Diabetologia. 2018 May;61(5):1193-1202. doi: 10.1007/s00125-018-4561-y. Epub 2018 Feb 5. Diabetologia. 2018. PMID: 29404673
Human enterovirus 71 strains in the background population and in hospital patients in Finland.
Honkanen H, Oikarinen S, Pakkanen O, Ruokoranta T, Pulkki MM, Laitinen OH, Tauriainen S, Korpela S, Lappalainen M, Vuorinen T, Haapala AM, Veijola R, Simell O, Ilonen J, Knip M, Hyöty H. Honkanen H, et al. Among authors: laitinen oh. J Clin Virol. 2013 Apr;56(4):348-53. doi: 10.1016/j.jcv.2012.11.018. Epub 2012 Dec 21. J Clin Virol. 2013. PMID: 23261080
A preclinical study on the efficacy and safety of a new vaccine against Coxsackievirus B1 reveals no risk for accelerated diabetes development in mouse models.
Larsson PG, Lakshmikanth T, Laitinen OH, Utorova R, Jacobson S, Oikarinen M, Domsgen E, Koivunen MR, Chaux P, Devard N, Lecouturier V, Almond J, Knip M, Hyöty H, Flodström-Tullberg M. Larsson PG, et al. Among authors: laitinen oh. Diabetologia. 2015 Feb;58(2):346-54. doi: 10.1007/s00125-014-3436-0. Epub 2014 Nov 5. Diabetologia. 2015. PMID: 25370797
Detection of enteroviruses in stools precedes islet autoimmunity by several months: possible evidence for slowly operating mechanisms in virus-induced autoimmunity.
Honkanen H, Oikarinen S, Nurminen N, Laitinen OH, Huhtala H, Lehtonen J, Ruokoranta T, Hankaniemi MM, Lecouturier V, Almond JW, Tauriainen S, Simell O, Ilonen J, Veijola R, Viskari H, Knip M, Hyöty H. Honkanen H, et al. Among authors: laitinen oh. Diabetologia. 2017 Mar;60(3):424-431. doi: 10.1007/s00125-016-4177-z. Epub 2017 Jan 9. Diabetologia. 2017. PMID: 28070615
A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses.
Saarinen NVV, Laiho JE, Richardson SJ, Zeissler M, Stone VM, Marjomäki V, Kantoluoto T, Horwitz MS, Sioofy-Khojine A, Honkimaa A, Hankaniemi MM, Flodström-Tullberg M, Hyöty H, Hytönen VP, Laitinen OH. Saarinen NVV, et al. Among authors: laitinen oh. Sci Rep. 2018 Jan 8;8(1):33. doi: 10.1038/s41598-017-18495-4. Sci Rep. 2018. PMID: 29311608 Free PMC article.
88 results