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A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation.
Elife. 2018 Feb 21;7:e32766. doi: 10.7554/eLife.32766.
Elife. 2018.
PMID: 29465396
Free PMC article.
Quantitative conformational profiling of kinase inhibitors reveals origins of selectivity for Aurora kinase activation states.
Lake EW, Muretta JM, Thompson AR, Rasmussen DM, Majumdar A, Faber EB, Ruff EF, Thomas DD, Levinson NM.
Lake EW, et al.
Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):E11894-E11903. doi: 10.1073/pnas.1811158115. Epub 2018 Dec 5.
Proc Natl Acad Sci U S A. 2018.
PMID: 30518564
Free PMC article.
Item in Clipboard
Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography.
Ubah OC, Lake EW, Gunaratne GS, Gallant JP, Fernie M, Robertson AJ, Marchant JS, Bold TD, Langlois RA, Matchett WE, Thiede JM, Shi K, Yin L, Moeller NH, Banerjee S, Ferguson L, Kovaleva M, Porter AJ, Aihara H, LeBeau AM, Barelle CJ.
Ubah OC, et al. Among authors: lake ew.
Nat Commun. 2021 Dec 16;12(1):7325. doi: 10.1038/s41467-021-27611-y.
Nat Commun. 2021.
PMID: 34916516
Free PMC article.
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Development of an Engineered Single-Domain Antibody for Targeting MET in Non-Small Cell Lung Cancer.
Luo NY, Minne RL, Gallant JP, Gunaratne GS, West JL, Javeri S, Robertson AJ, Lake EW, Engle JW, Mixdorf JC, Aluicio-Sarduy E, Nickel KP, Hernandez R, Kimple RJ, Baschnagel AM, LeBeau AM.
Luo NY, et al. Among authors: lake ew.
Bioconjug Chem. 2024 Mar 20;35(3):389-399. doi: 10.1021/acs.bioconjchem.4c00019. Epub 2024 Mar 12.
Bioconjug Chem. 2024.
PMID: 38470611
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Provider documentation of patient education: a lean investigation.
Shipman JP, Lake EW, Van Der Volgen J, Doman D.
Shipman JP, et al. Among authors: lake ew.
J Med Libr Assoc. 2016 Apr;104(2):154-8. doi: 10.3163/1536-5050.104.2.012.
J Med Libr Assoc. 2016.
PMID: 27076805
Free PMC article.
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Renal tubule cell repair following acute renal injury.
Humes HD, Lake EW, Liu S.
Humes HD, et al. Among authors: lake ew.
Miner Electrolyte Metab. 1995;21(4-5):353-65.
Miner Electrolyte Metab. 1995.
PMID: 7565484
Review.
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Acute renal failure: directed therapy to enhance renal tubular regeneration.
Lake EW, Humes HD.
Lake EW, et al.
Semin Nephrol. 1994 Jan;14(1):83-97.
Semin Nephrol. 1994.
PMID: 8140345
No abstract available.
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