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Single cell RNA-sequencing of Ewing sarcoma tumors demonstrates transcriptional heterogeneity and clonal evolution.
Goodspeed A, Bodlak A, Duffy AB, Nelson-Taylor S, Oike N, Porfilio T, Shirai R, Walker D, Treece A, Black J, Donaldson N, Cost C, Garrington T, Greffe B, Luna-Fineman S, Demedis J, Lake J, Danis EP, Verneris M, Adams DL, Hayashi M. Goodspeed A, et al. Among authors: lake j. Clin Cancer Res. 2025 Mar 3. doi: 10.1158/1078-0432.CCR-24-2040. Online ahead of print. Clin Cancer Res. 2025. PMID: 40029262
Characterization of transcriptional heterogeneity and novel therapeutic targets using single cell RNA-sequencing of primary and circulating Ewing sarcoma cells.
Goodspeed A, Bodlak A, Duffy AB, Nelson-Taylor S, Oike N, Porfilio T, Shirai R, Walker D, Treece A, Black J, Donaldson N, Cost C, Garrington T, Greffe B, Luna-Fineman S, Demedis J, Lake J, Danis E, Verneris M, Adams DL, Hayashi M. Goodspeed A, et al. Among authors: lake j. bioRxiv [Preprint]. 2024 Jun 20:2024.01.18.576251. doi: 10.1101/2024.01.18.576251. bioRxiv. 2024. PMID: 38293103 Free PMC article. Preprint.
Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors.
Lake JA, Donson AM, Prince E, Davies KD, Nellan A, Green AL, Mulcahy Levy J, Dorris K, Vibhakar R, Hankinson TC, Foreman NK, Ewalt MD, Kleinschmidt-DeMasters BK, Hoffman LM, Gilani A. Lake JA, et al. Pediatr Blood Cancer. 2020 Jan;67(1):e28028. doi: 10.1002/pbc.28028. Epub 2019 Oct 8. Pediatr Blood Cancer. 2020. PMID: 31595628 Free PMC article.
Targetable molecular alterations in congenital glioblastoma.
Gilani A, Donson A, Davies KD, Whiteway SL, Lake J, DeSisto J, Hoffman L, Foreman NK, Kleinschmidt-DeMasters BK, Green AL. Gilani A, et al. Among authors: lake j. J Neurooncol. 2020 Jan;146(2):247-252. doi: 10.1007/s11060-019-03377-8. Epub 2019 Dec 24. J Neurooncol. 2020. PMID: 31875306
1,043 results