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Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal.
Pietras EM, Mirantes-Barbeito C, Fong S, Loeffler D, Kovtonyuk LV, Zhang S, Lakshminarasimhan R, Chin CP, Techner JM, Will B, Nerlov C, Steidl U, Manz MG, Schroeder T, Passegué E. Pietras EM, et al. Among authors: lakshminarasimhan r. Nat Cell Biol. 2016 Jun;18(6):607-18. doi: 10.1038/ncb3346. Epub 2016 Apr 25. Nat Cell Biol. 2016. PMID: 27111842 Free PMC article.
The Role of DNA Methylation in Cancer.
Lakshminarasimhan R, Liang G. Lakshminarasimhan R, et al. Adv Exp Med Biol. 2016;945:151-172. doi: 10.1007/978-3-319-43624-1_7. Adv Exp Med Biol. 2016. PMID: 27826838 Free PMC article. Review.
Identifying aggressive prostate cancer foci using a DNA methylation classifier.
Mundbjerg K, Chopra S, Alemozaffar M, Duymich C, Lakshminarasimhan R, Nichols PW, Aron M, Siegmund KD, Ukimura O, Aron M, Stern M, Gill P, Carpten JD, Ørntoft TF, Sørensen KD, Weisenberger DJ, Jones PA, Duddalwar V, Gill I, Liang G. Mundbjerg K, et al. Among authors: lakshminarasimhan r. Genome Biol. 2017 Jan 12;18(1):3. doi: 10.1186/s13059-016-1129-3. Genome Biol. 2017. PMID: 28081708 Free PMC article.
Insights into the Pathogenesis of Anaplastic Large-Cell Lymphoma through Genome-wide DNA Methylation Profiling.
Hassler MR, Pulverer W, Lakshminarasimhan R, Redl E, Hacker J, Garland GD, Merkel O, Schiefer AI, Simonitsch-Klupp I, Kenner L, Weisenberger DJ, Weinhaeusel A, Turner SD, Egger G. Hassler MR, et al. Among authors: lakshminarasimhan r. Cell Rep. 2016 Oct 4;17(2):596-608. doi: 10.1016/j.celrep.2016.09.018. Cell Rep. 2016. PMID: 27705804 Free PMC article.