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A role for asymmetric dimethylarginine in the pathophysiology of portal hypertension in rats with biliary cirrhosis.
Laleman W, Omasta A, Van de Casteele M, Zeegers M, Vander Elst I, Van Landeghem L, Severi T, van Pelt J, Roskams T, Fevery J, Nevens F. Laleman W, et al. Hepatology. 2005 Dec;42(6):1382-90. doi: 10.1002/hep.20968. Hepatology. 2005. PMID: 16317694
Portal hypertension: from pathophysiology to clinical practice.
Laleman W, Landeghem L, Wilmer A, Fevery J, Nevens F. Laleman W, et al. Liver Int. 2005 Dec;25(6):1079-90. doi: 10.1111/j.1478-3231.2005.01163.x. Liver Int. 2005. PMID: 16343056 Review.
A stable model of cirrhotic portal hypertension in the rat: thioacetamide revisited.
Laleman W, Vander Elst I, Zeegers M, Servaes R, Libbrecht L, Roskams T, Fevery J, Nevens F. Laleman W, et al. Eur J Clin Invest. 2006 Apr;36(4):242-9. doi: 10.1111/j.1365-2362.2006.01620.x. Eur J Clin Invest. 2006. PMID: 16620286
Nitroflurbiprofen, a nitric oxide-releasing cyclooxygenase inhibitor, improves cirrhotic portal hypertension in rats.
Laleman W, Van Landeghem L, Van der Elst I, Zeegers M, Fevery J, Nevens F. Laleman W, et al. Gastroenterology. 2007 Feb;132(2):709-19. doi: 10.1053/j.gastro.2006.12.041. Epub 2006 Dec 20. Gastroenterology. 2007. PMID: 17258737
Atorvastatin lowers portal pressure in cirrhotic rats by inhibition of RhoA/Rho-kinase and activation of endothelial nitric oxide synthase.
Trebicka J, Hennenberg M, Laleman W, Shelest N, Biecker E, Schepke M, Nevens F, Sauerbruch T, Heller J. Trebicka J, et al. Hepatology. 2007 Jul;46(1):242-53. doi: 10.1002/hep.21673. Hepatology. 2007. PMID: 17596891
Carbon monoxide produced by intrasinusoidally located haem-oxygenase-1 regulates the vascular tone in cirrhotic rat liver.
Van Landeghem L, Laleman W, Vander Elst I, Zeegers M, van Pelt J, Cassiman D, Nevens F. Van Landeghem L, et al. Liver Int. 2009 May;29(5):650-60. doi: 10.1111/j.1478-3231.2008.01857.x. Epub 2008 Sep 15. Liver Int. 2009. PMID: 18795901
Role of beta3-adrenoceptors for intrahepatic resistance and portal hypertension in liver cirrhosis.
Trebicka J, Hennenberg M, Schulze Pröbsting A, Laleman W, Klein S, Granzow M, Nevens F, Zaagsma J, Heller J, Sauerbruch T. Trebicka J, et al. Hepatology. 2009 Dec;50(6):1924-35. doi: 10.1002/hep.23222. Hepatology. 2009. PMID: 19842096
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