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The neural chaperone proSAAS blocks α-synuclein fibrillation and neurotoxicity.
Jarvela TS, Lam HA, Helwig M, Lorenzen N, Otzen DE, McLean PJ, Maidment NT, Lindberg I. Jarvela TS, et al. Among authors: lam ha. Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4708-15. doi: 10.1073/pnas.1601091113. Epub 2016 Jul 25. Proc Natl Acad Sci U S A. 2016. PMID: 27457957 Free PMC article.
Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease.
Fitzmaurice AG, Rhodes SL, Lulla A, Murphy NP, Lam HA, O'Donnell KC, Barnhill L, Casida JE, Cockburn M, Sagasti A, Stahl MC, Maidment NT, Ritz B, Bronstein JM. Fitzmaurice AG, et al. Among authors: lam ha. Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):636-41. doi: 10.1073/pnas.1220399110. Epub 2012 Dec 24. Proc Natl Acad Sci U S A. 2013. PMID: 23267077 Free PMC article.
Elevated tonic extracellular dopamine concentration and altered dopamine modulation of synaptic activity precede dopamine loss in the striatum of mice overexpressing human α-synuclein.
Lam HA, Wu N, Cely I, Kelly RL, Hean S, Richter F, Magen I, Cepeda C, Ackerson LC, Walwyn W, Masliah E, Chesselet MF, Levine MS, Maidment NT. Lam HA, et al. J Neurosci Res. 2011 Jul;89(7):1091-102. doi: 10.1002/jnr.22611. Epub 2011 Apr 12. J Neurosci Res. 2011. PMID: 21488084 Free PMC article.
46 results