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The CCN family of angiogenic regulators: the integrin connection.
Lau LF, Lam SC. Lau LF, et al. Among authors: lam sc. Exp Cell Res. 1999 Apr 10;248(1):44-57. doi: 10.1006/excr.1999.4456. Exp Cell Res. 1999. PMID: 10094812 Review. No abstract available.
TA205, an anti-talin monoclonal antibody, inhibits integrin-talin interaction.
Xing B, Thuppal S, Jedsadayanmata A, Du X, Lam SC. Xing B, et al. Among authors: lam sc. FEBS Lett. 2006 Apr 3;580(8):2027-32. doi: 10.1016/j.febslet.2006.02.077. Epub 2006 Mar 10. FEBS Lett. 2006. PMID: 16546176
The role of integrin alpha D beta2 (CD11d/CD18) in monocyte/macrophage migration.
Yakubenko VP, Belevych N, Mishchuk D, Schurin A, Lam SC, Ugarova TP. Yakubenko VP, et al. Among authors: lam sc. Exp Cell Res. 2008 Aug 15;314(14):2569-78. doi: 10.1016/j.yexcr.2008.05.016. Epub 2008 Jun 4. Exp Cell Res. 2008. PMID: 18621369 Free PMC article.
Identification of a novel integrin alphaMbeta2 binding site in CCN1 (CYR61), a matricellular protein expressed in healing wounds and atherosclerotic lesions.
Schober JM, Lau LF, Ugarova TP, Lam SC. Schober JM, et al. Among authors: lam sc. J Biol Chem. 2003 Jul 11;278(28):25808-15. doi: 10.1074/jbc.M301534200. Epub 2003 May 6. J Biol Chem. 2003. PMID: 12736251
A directional switch of integrin signalling and a new anti-thrombotic strategy.
Shen B, Zhao X, O'Brien KA, Stojanovic-Terpo A, Delaney MK, Kim K, Cho J, Lam SC, Du X. Shen B, et al. Among authors: lam sc. Nature. 2013 Nov 7;503(7474):131-5. doi: 10.1038/nature12613. Epub 2013 Oct 27. Nature. 2013. PMID: 24162846 Free PMC article.
Tyrosine phosphorylation of the integrin beta 3 subunit regulates beta 3 cleavage by calpain.
Xi X, Flevaris P, Stojanovic A, Chishti A, Phillips DR, Lam SC, Du X. Xi X, et al. Among authors: lam sc. J Biol Chem. 2006 Oct 6;281(40):29426-30. doi: 10.1074/jbc.C600039200. Epub 2006 Aug 25. J Biol Chem. 2006. PMID: 16935858
Targeted mutagenesis of the angiogenic protein CCN1 (CYR61). Selective inactivation of integrin alpha6beta1-heparan sulfate proteoglycan coreceptor-mediated cellular functions.
Leu SJ, Chen N, Chen CC, Todorovic V, Bai T, Juric V, Liu Y, Yan G, Lam SC, Lau LF. Leu SJ, et al. Among authors: lam sc. J Biol Chem. 2004 Oct 15;279(42):44177-87. doi: 10.1074/jbc.M407850200. Epub 2004 Aug 17. J Biol Chem. 2004. PMID: 15322081
Identification of a novel integrin alphavbeta3 binding site in CCN1 (CYR61) critical for pro-angiogenic activities in vascular endothelial cells.
Chen N, Leu SJ, Todorovic V, Lam SC, Lau LF. Chen N, et al. Among authors: lam sc. J Biol Chem. 2004 Oct 15;279(42):44166-76. doi: 10.1074/jbc.M406813200. Epub 2004 Aug 10. J Biol Chem. 2004. PMID: 15308622
Critical roles for the COOH-terminal NITY and RGT sequences of the integrin beta3 cytoplasmic domain in inside-out and outside-in signaling.
Xi X, Bodnar RJ, Li Z, Lam SC, Du X. Xi X, et al. Among authors: lam sc. J Cell Biol. 2003 Jul 21;162(2):329-39. doi: 10.1083/jcb.200303120. Epub 2003 Jul 14. J Cell Biol. 2003. PMID: 12860973 Free PMC article.
Identification of a novel integrin alpha 6 beta 1 binding site in the angiogenic inducer CCN1 (CYR61).
Leu SJ, Liu Y, Chen N, Chen CC, Lam SC, Lau LF. Leu SJ, et al. Among authors: lam sc. J Biol Chem. 2003 Sep 5;278(36):33801-8. doi: 10.1074/jbc.M305862200. Epub 2003 Jun 24. J Biol Chem. 2003. PMID: 12826661
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