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A human peroxisome-proliferator-activated receptor-gamma is activated by inducers of adipogenesis, including thiazolidinedione drugs.
Lambe KG, Tugwood JD. Lambe KG, et al. Eur J Biochem. 1996 Jul 1;239(1):1-7. doi: 10.1111/j.1432-1033.1996.0001u.x. Eur J Biochem. 1996. PMID: 8706692 Free article.
Apoptosis and proliferation in nongenotoxic carcinogenesis: species differences and role of PPARalpha.
Roberts RA, James NH, Hasmall SC, Holden PR, Lambe K, Macdonald N, West D, Woodyatt NJ, Whitcome D. Roberts RA, et al. Among authors: lambe k. Toxicol Lett. 2000 Mar 15;112-113:49-57. doi: 10.1016/s0378-4274(99)00243-x. Toxicol Lett. 2000. PMID: 10720712 Review.
Species differences in sequence and activity of the peroxisome proliferator response element (PPRE) within the acyl CoA oxidase gene promoter.
Lambe KG, Woodyatt NJ, Macdonald N, Chevalier S, Roberts RA. Lambe KG, et al. Toxicol Lett. 1999 Oct 29;110(1-2):119-27. doi: 10.1016/s0378-4274(99)00151-4. Toxicol Lett. 1999. PMID: 10593603
The peroxisome proliferator (PP) response element upstream of the human acyl CoA oxidase gene is inactive among a sample human population: significance for species differences in response to PPs.
Woodyatt NJ, Lambe KG, Myers KA, Tugwood JD, Roberts RA. Woodyatt NJ, et al. Among authors: lambe kg. Carcinogenesis. 1999 Mar;20(3):369-72. doi: 10.1093/carcin/20.3.369. Carcinogenesis. 1999. PMID: 10190548
Peroxisome proliferator-activated receptor-alpha and the pleiotropic responses to peroxisome proliferators.
Tugwood JD, Aldridge TC, Lambe KG, Macdonald N, Woodyatt NJ. Tugwood JD, et al. Among authors: lambe kg. Arch Toxicol Suppl. 1998;20:377-86. doi: 10.1007/978-3-642-46856-8_33. Arch Toxicol Suppl. 1998. PMID: 9442309 No abstract available.
Amino acid residues in both the DNA-binding and ligand-binding domains influence transcriptional activity of the human peroxisome proliferator-activated receptor alpha.
Myers KA, Lambe KG, Aldridge TC, Macdonald N, Tugwood JD. Myers KA, et al. Among authors: lambe kg. Biochem Biophys Res Commun. 1997 Oct 20;239(2):522-6. doi: 10.1006/bbrc.1997.7507. Biochem Biophys Res Commun. 1997. PMID: 9344863
Peroxisome proliferator-activated receptors: structures and function.
Tugwood JD, Aldridge TC, Lambe KG, Macdonald N, Woodyatt NJ. Tugwood JD, et al. Among authors: lambe kg. Ann N Y Acad Sci. 1996 Dec 27;804:252-65. doi: 10.1111/j.1749-6632.1996.tb18620.x. Ann N Y Acad Sci. 1996. PMID: 8993548