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New developments for antibody-drug conjugate-based therapeutic approaches.
de Goeij BE, Lambert JM. de Goeij BE, et al. Among authors: lambert jm. Curr Opin Immunol. 2016 Jun;40:14-23. doi: 10.1016/j.coi.2016.02.008. Epub 2016 Mar 7. Curr Opin Immunol. 2016. PMID: 26963132 Review.
Eradication of large colon tumor xenografts by targeted delivery of maytansinoids.
Liu C, Tadayoni BM, Bourret LA, Mattocks KM, Derr SM, Widdison WC, Kedersha NL, Ariniello PD, Goldmacher VS, Lambert JM, Blättler WA, Chari RV. Liu C, et al. Among authors: lambert jm. Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8618-23. doi: 10.1073/pnas.93.16.8618. Proc Natl Acad Sci U S A. 1996. PMID: 8710920 Free PMC article.
Cure of multidrug-resistant human B-cell lymphoma xenografts by combinations of anti-B4-blocked ricin and chemotherapeutic drugs.
Liu C, Lambert JM, Teicher BA, Blättler WA, O'Connor R. Liu C, et al. Among authors: lambert jm. Blood. 1996 May 1;87(9):3892-8. Blood. 1996. PMID: 8611717
Realizing the full potential of immunotoxins.
Blättler WA, Lambert JM, Goldmacher VS. Blättler WA, et al. Among authors: lambert jm. Cancer Cells. 1989 Oct;1(2):50-5. Cancer Cells. 1989. PMID: 2701364 Review.
The INNs and outs of antibody nonproprietary names.
Jones TD, Carter PJ, Plückthun A, Vásquez M, Holgate RG, Hötzel I, Popplewell AG, Parren PW, Enzelberger M, Rademaker HJ, Clark MR, Lowe DC, Dahiyat BI, Smith V, Lambert JM, Wu H, Reilly M, Haurum JS, Dübel S, Huston JS, Schirrmann T, Janssen RA, Steegmaier M, Gross JA, Bradbury AR, Burton DR, Dimitrov DS, Chester KA, Glennie MJ, Davies J, Walker A, Martin S, McCafferty J, Baker MP. Jones TD, et al. Among authors: lambert jm. MAbs. 2016;8(1):1-9. doi: 10.1080/19420862.2015.1114320. MAbs. 2016. PMID: 26716992 Free PMC article.
Antibody-Drug Conjugates (ADCs): Magic Bullets at Last!
Lambert JM. Lambert JM. Mol Pharm. 2015 Jun 1;12(6):1701-2. doi: 10.1021/acs.molpharmaceut.5b00302. Mol Pharm. 2015. PMID: 26027696 No abstract available.
Antibody-drug conjugates: targeted delivery and future prospects.
Lambert JM. Lambert JM. Ther Deliv. 2016;7(5):279-82. doi: 10.4155/tde-2016-0010. Ther Deliv. 2016. PMID: 27075948 No abstract available.
Understanding How the Stability of the Thiol-Maleimide Linkage Impacts the Pharmacokinetics of Lysine-Linked Antibody-Maytansinoid Conjugates.
Ponte JF, Sun X, Yoder NC, Fishkin N, Laleau R, Coccia J, Lanieri L, Bogalhas M, Wang L, Wilhelm S, Widdison W, Pinkas J, Keating TA, Chari R, Erickson HK, Lambert JM. Ponte JF, et al. Among authors: lambert jm. Bioconjug Chem. 2016 Jul 20;27(7):1588-98. doi: 10.1021/acs.bioconjchem.6b00117. Epub 2016 Jun 20. Bioconjug Chem. 2016. PMID: 27174129
Effects of Drug-Antibody Ratio on Pharmacokinetics, Biodistribution, Efficacy, and Tolerability of Antibody-Maytansinoid Conjugates.
Sun X, Ponte JF, Yoder NC, Laleau R, Coccia J, Lanieri L, Qiu Q, Wu R, Hong E, Bogalhas M, Wang L, Dong L, Setiady Y, Maloney EK, Ab O, Zhang X, Pinkas J, Keating TA, Chari R, Erickson HK, Lambert JM. Sun X, et al. Among authors: lambert jm. Bioconjug Chem. 2017 May 17;28(5):1371-1381. doi: 10.1021/acs.bioconjchem.7b00062. Epub 2017 Apr 13. Bioconjug Chem. 2017. PMID: 28388844
Antibody-Drug Conjugates (ADCs) for Personalized Treatment of Solid Tumors: A Review.
Lambert JM, Morris CQ. Lambert JM, et al. Adv Ther. 2017 May;34(5):1015-1035. doi: 10.1007/s12325-017-0519-6. Epub 2017 Mar 30. Adv Ther. 2017. PMID: 28361465 Free PMC article. Review.
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