Lambrot R - Search Results

1

Histone H3 lysine 4 trimethylation in sperm is transmitted to the embryo and associated with diet-induced phenotypes in the offspring.

Lismer A, Dumeaux V, Lafleur C, Lambrot R, Brind'Amour J, Lorincz MC, Kimmins S. Lismer A, et al. Among authors: lambrot r. Dev Cell. 2021 Mar 8;56(5):671-686.e6. doi: 10.1016/j.devcel.2021.01.014. Epub 2021 Feb 16. Dev Cell. 2021. PMID: 33596408 Free article.

2

Disruption of histone methylation in developing sperm impairs offspring health transgenerationally.

Siklenka K, Erkek S, Godmann M, Lambrot R, McGraw S, Lafleur C, Cohen T, Xia J, Suderman M, Hallett M, Trasler J, Peters AH, Kimmins S. Siklenka K, et al. Among authors: lambrot r. Science. 2015 Nov 6;350(6261):aab2006. doi: 10.1126/science.aab2006. Epub 2015 Oct 8. Science. 2015. PMID: 26449473

3

The genomic distribution of histone H3K4me2 in spermatogonia is highly conserved in sperm†.

Lambrot R, Siklenka K, Lafleur C, Kimmins S. Lambrot R, et al. Biol Reprod. 2019 Jun 1;100(6):1661-1672. doi: 10.1093/biolre/ioz055. Biol Reprod. 2019. PMID: 30951591

4

ChIP-seq protocol for sperm cells and embryos to assess environmental impacts and epigenetic inheritance.

Lismer A, Lambrot R, Lafleur C, Dumeaux V, Kimmins S. Lismer A, et al. Among authors: lambrot r. STAR Protoc. 2021 Jun 11;2(2):100602. doi: 10.1016/j.xpro.2021.100602. eCollection 2021 Jun 18. STAR Protoc. 2021. PMID: 34159325 Free PMC article.

5

Whole-genome sequencing of H3K4me3 and DNA methylation in human sperm reveals regions of overlap linked to fertility and development.

Lambrot R, Chan D, Shao X, Aarabi M, Kwan T, Bourque G, Moskovtsev S, Librach C, Trasler J, Dumeaux V, Kimmins S. Lambrot R, et al. Cell Rep. 2021 Jul 20;36(3):109418. doi: 10.1016/j.celrep.2021.109418. Cell Rep. 2021. PMID: 34289352 Free article.

6

Sperm histone H3 lysine 4 tri-methylation serves as a metabolic sensor of paternal obesity and is associated with the inheritance of metabolic dysfunction.

Pepin AS, Lafleur C, Lambrot R, Dumeaux V, Kimmins S. Pepin AS, et al. Among authors: lambrot r. Mol Metab. 2022 May;59:101463. doi: 10.1016/j.molmet.2022.101463. Epub 2022 Feb 17. Mol Metab. 2022. PMID: 35183795 Free PMC article.

7

Histone methylation is a critical regulator of the abnormal expression of POU5F1 and RASSF1A in testis cancer cell lines.

Lambrot R, Kimmins S. Lambrot R, et al. Int J Androl. 2011 Apr;34(2):110-23. doi: 10.1111/j.1365-2605.2010.01063.x. Int J Androl. 2011. PMID: 20497257

8

Specialized distribution of the histone methyltransferase Ezh2 in the nuclear apical region of round spermatids and its interaction with the histone variant H1t2.

Lambrot R, Jones S, Saint-Phar S, Kimmins S. Lambrot R, et al. J Androl. 2012 Sep-Oct;33(5):1058-66. doi: 10.2164/jandrol.111.013870. Epub 2012 Feb 9. J Androl. 2012. PMID: 22323620

9

The histone demethylase KDM1A is essential for the maintenance and differentiation of spermatogonial stem cells and progenitors.

Lambrot R, Lafleur C, Kimmins S. Lambrot R, et al. FASEB J. 2015 Nov;29(11):4402-16. doi: 10.1096/fj.14-267328. Epub 2015 Aug 4. FASEB J. 2015. PMID: 26243864

10

The dynamic epigenetic program in male germ cells: Its role in spermatogenesis, testis cancer, and its response to the environment.

Godmann M, Lambrot R, Kimmins S. Godmann M, et al. Among authors: lambrot r. Microsc Res Tech. 2009 Aug;72(8):603-19. doi: 10.1002/jemt.20715. Microsc Res Tech. 2009. PMID: 19319879 Review.

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