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Laminaria japonica Polysaccharide Suppresses Atherosclerosis via Regulating Autophagy-Mediated Macrophage Polarization.
Li XY, Wang YJ, Chen S, Pan LH, Li QM, Luo JP, Zha XQ. Li XY, et al. J Agric Food Chem. 2022 Mar 30;70(12):3633-3643. doi: 10.1021/acs.jafc.1c07483. Epub 2022 Feb 15. J Agric Food Chem. 2022. PMID: 35167294
The present work aimed to explore the effect and underlying mechanism of a homogeneous Laminaria japonica polysaccharide (LJP61A) on macrophage polarization in high-fat-diet-fed LDLr(-/-) mice and Ox-LDL-induced macrophages. ...These results suggested that LJP61A re …
The present work aimed to explore the effect and underlying mechanism of a homogeneous Laminaria japonica polysaccharide (LJP6 …
Inhibition of Ca(2+)-calpain signaling is a new mechanism using Laminaria japonica polysaccharide to prevent macrophage foam cell formation and atherosclerosis.
Li XY, Kuang DD, Guo AJ, Deng YY, Pan LH, Li QM, Luo JP, Zha XQ. Li XY, et al. Food Funct. 2023 May 11;14(9):4036-4048. doi: 10.1039/d2fo04099a. Food Funct. 2023. PMID: 37067393
The aim of the current work was to investigate the role of Ca(2+)-calpain signaling in the regulation of macrophage autophagy by a Laminaria japonica polysaccharide (LJP61A) in Ox-LDL induced macrophages and high fat diet fed atherosclerotic mice. ...These findings …
The aim of the current work was to investigate the role of Ca(2+)-calpain signaling in the regulation of macrophage autophagy by a Lamina …
Purification, structure features and anti-atherosclerosis activity of a Laminaria japonica polysaccharide.
Peng FH, Zha XQ, Cui SH, Asghar MN, Pan LH, Wang JH, Luo JP. Peng FH, et al. Int J Biol Macromol. 2015 Nov;81:926-35. doi: 10.1016/j.ijbiomac.2015.09.027. Epub 2015 Sep 21. Int J Biol Macromol. 2015. PMID: 26394383
A homogeneous polysaccharide (LJP12) was isolated from Laminaria japonica by diethylaminoethyl-cellulose and Sephacryl S-500 chromatography, with a molecular weight of 2.31 10(6)Da. ...Taken together, we concluded that long-term oral administration of LJP12 protects …
A homogeneous polysaccharide (LJP12) was isolated from Laminaria japonica by diethylaminoethyl-cellulose and Sephacryl S-500 c …
The Effect of Laminaria japonica on Metabolic Syndrome: A Systematic Review of Its Efficacy and Mechanism of Action.
Lee IS, Ko SJ, Lee YN, Lee G, Rahman H, Kim B. Lee IS, et al. Nutrients. 2022 Jul 25;14(15):3046. doi: 10.3390/nu14153046. Nutrients. 2022. PMID: 35893900 Free PMC article.
In accordance with recent studies, the brown seaweed Laminaria japonica (LJP) has anti-inflammatory and antioxidant properties, and so forth. ...
In accordance with recent studies, the brown seaweed Laminaria japonica (LJP) has anti-inflammatory and antioxidant properties …
Alleviating VLDL overproduction is an important mechanism for Laminaria japonica polysaccharide to inhibit atherosclerosis in LDLr(-/-) mice with diet-induced insulin resistance.
Zha XQ, Zhang WN, Peng FH, Xue L, Liu J, Luo JP. Zha XQ, et al. Mol Nutr Food Res. 2017 Apr;61(4). doi: 10.1002/mnfr.201600456. Epub 2017 Feb 8. Mol Nutr Food Res. 2017. PMID: 27928899
SCOPE: The overproduction of very low density lipoprotein (VLDL) is an important cause for initiation and development of atherosclerosis, which is highly associated with insulin signaling. The aim of this work is to verify whether the inhibition of VLDL overproduction is a …
SCOPE: The overproduction of very low density lipoprotein (VLDL) is an important cause for initiation and development of atherosclerosis …
Laminaria japonica polysaccharide prevents high-fat-diet-induced insulin resistance in mice via regulating gut microbiota.
Li QM , Zha XQ , Zhang WN , Liu J , Pan LH , Luo JP . Li QM , et al. Food Funct. 2021 Jun 21;12(12):5260-5273. doi: 10.1039/d0fo02100h. Epub 2021 May 17. Food Funct. 2021. PMID: 33999048
Insulin resistance has become a worldwide nutrition and metabolic health problem due to the lack of effective protective agents. Laminaria japonica is a well-known marine vegetable. Purified Laminaria japonica polysaccharide (LJP61A) can inhibit ath …
Insulin resistance has become a worldwide nutrition and metabolic health problem due to the lack of effective protective agents. Laminari …
[Effect of Laminaria japonica polysaccharides on lowing serum lipid and anti-atherosclerosis in hyperlipemia quails].
Li C, Gao Y, Li M, Shi W, Liu Z. Li C, et al. Zhong Yao Cai. 2005 Aug;28(8):676-9. Zhong Yao Cai. 2005. PMID: 16379420 Chinese.
OBJECTIVE: To study the effect of Laminaria Japonica Polysaccharides on lowing serum lipid and anti-atherosclerosis in quails. ...RESULTS: The concentration of TC, TG, LDL in serum and index of liver decreased remarkedly, the ratio of HLD/TC increased remarka …
OBJECTIVE: To study the effect of Laminaria Japonica Polysaccharides on lowing serum lipid and anti-atherosclerosis in …
A comparative study of the hypolipidemic effects and mechanisms of action of Laminaria japonica- and Ascophyllum nodosum-derived fucoidans in apolipoprotein E-deficient mice.
Liu T, Wang X, Wang YM, Sui FR, Zhang XY, Liu HD, Ma DY, Liu XX, Guo SD. Liu T, et al. Food Funct. 2024 Jun 4;15(11):5955-5971. doi: 10.1039/d3fo05521c. Food Funct. 2024. PMID: 38738998
Previous studies have demonstrated that Laminaria japonica- and Ascophyllum nodosum-derived fucoidans have type I and type II fucosyl chains, respectively. ...
Previous studies have demonstrated that Laminaria japonica- and Ascophyllum nodosum-derived fucoidans have type I and type II …
The protective mechanisms of macroalgae Laminaria japonica consumption against lipid metabolism disorders in high-fat diet-induced hyperlipidemic rats.
Zhang Q, Fan XY, Guo WL, Cao YJ, Lin YC, Cheng WJ, Chen LJ, Rao PF, Ni L, Lv XC. Zhang Q, et al. Food Funct. 2020 Apr 30;11(4):3256-3270. doi: 10.1039/d0fo00065e. Food Funct. 2020. PMID: 32219261
Macroalgae Laminaria japonica (MLJ) has been reported to exhibit various biological activities including improving immunity, anti-aging, anti-tumor, anti-atherosclerosis and anti-diabetic, but the protective mechanisms of MLJ consumption against non-alcoholic …
Macroalgae Laminaria japonica (MLJ) has been reported to exhibit various biological activities including improving immunity, a …
14 results