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Laminaria japonica Polysaccharide Suppresses Atherosclerosis via Regulating Autophagy-Mediated Macrophage Polarization.
Li XY, Wang YJ, Chen S, Pan LH, Li QM, Luo JP, Zha XQ. Li XY, et al. J Agric Food Chem. 2022 Mar 30;70(12):3633-3643. doi: 10.1021/acs.jafc.1c07483. Epub 2022 Feb 15. J Agric Food Chem. 2022. PMID: 35167294
The present work aimed to explore the effect and underlying mechanism of a homogeneous Laminaria japonica polysaccharide (LJP61A) on macrophage polarization in high-fat-diet-fed LDLr(-/-) mice and Ox-LDL-induced macrophages. ...However, these effects of LJP61A were …
The present work aimed to explore the effect and underlying mechanism of a homogeneous Laminaria japonica polysaccharide (LJP6 …
Polysaccharides from Laminaria japonica: an insight into the current research on structural features and biological properties.
Luan F , Zou J , Rao Z , Ji Y , Lei Z , Peng L , Yang Y , He X , Zeng N . Luan F , et al. Food Funct. 2021 May 21;12(10):4254-4283. doi: 10.1039/d1fo00311a. Epub 2021 Apr 27. Food Funct. 2021. PMID: 33904556 Review.
Laminaria japonica, one of the most widespread seafood consumed in China and many other nations, has been traditionally utilized as an effective therapeutically active substance for treating weight loss, phlegm elimination, and detumescence for more than 2000 years. …
Laminaria japonica, one of the most widespread seafood consumed in China and many other nations, has been traditionally utiliz …
Purification, structure features and anti-atherosclerosis activity of a Laminaria japonica polysaccharide.
Peng FH, Zha XQ, Cui SH, Asghar MN, Pan LH, Wang JH, Luo JP. Peng FH, et al. Int J Biol Macromol. 2015 Nov;81:926-35. doi: 10.1016/j.ijbiomac.2015.09.027. Epub 2015 Sep 21. Int J Biol Macromol. 2015. PMID: 26394383
A homogeneous polysaccharide (LJP12) was isolated from Laminaria japonica by diethylaminoethyl-cellulose and Sephacryl S-500 chromatography, with a molecular weight of 2.3110(6)Da. ...Taken together, we concluded that long-term oral administration of LJP12 protects …
A homogeneous polysaccharide (LJP12) was isolated from Laminaria japonica by diethylaminoethyl-cellulose and Sephacryl S-500 c …
The Effect of Laminaria japonica on Metabolic Syndrome: A Systematic Review of Its Efficacy and Mechanism of Action.
Lee IS, Ko SJ, Lee YN, Lee G, Rahman H, Kim B. Lee IS, et al. Nutrients. 2022 Jul 25;14(15):3046. doi: 10.3390/nu14153046. Nutrients. 2022. PMID: 35893900 Free PMC article. Review.
However, there is currently no cure for MetS, and the absence of immediate treatment for MetS has prompted the development of novel therapies. In accordance with recent studies, the brown seaweed Laminaria japonica (LJP) has anti-inflammatory and antioxidant propert …
However, there is currently no cure for MetS, and the absence of immediate treatment for MetS has prompted the development of novel therapie …
Laminaria japonica polysaccharide prevents high-fat-diet-induced insulin resistance in mice via regulating gut microbiota.
Li QM , Zha XQ , Zhang WN , Liu J , Pan LH , Luo JP . Li QM , et al. Food Funct. 2021 Jun 21;12(12):5260-5273. doi: 10.1039/d0fo02100h. Epub 2021 May 17. Food Funct. 2021. PMID: 33999048
Insulin resistance has become a worldwide nutrition and metabolic health problem due to the lack of effective protective agents. Laminaria japonica is a well-known marine vegetable. Purified Laminaria japonica polysaccharide (LJP61A) can inhibit ath …
Insulin resistance has become a worldwide nutrition and metabolic health problem due to the lack of effective protective agents. Laminari …
Alleviating VLDL overproduction is an important mechanism for Laminaria japonica polysaccharide to inhibit atherosclerosis in LDLr-/- mice with diet-induced insulin resistance.
Zha XQ, Zhang WN, Peng FH, Xue L, Liu J, Luo JP. Zha XQ, et al. Mol Nutr Food Res. 2017 Apr;61(4). doi: 10.1002/mnfr.201600456. Epub 2017 Feb 8. Mol Nutr Food Res. 2017. PMID: 27928899
SCOPE: The overproduction of very low density lipoprotein (VLDL) is an important cause for initiation and development of atherosclerosis, which is highly associated with insulin signaling. The aim of this work is to verify whether the inhibition of VLDL overproduction is a …
SCOPE: The overproduction of very low density lipoprotein (VLDL) is an important cause for initiation and development of atherosclerosis …
[Effect of Laminaria japonica polysaccharides on lowing serum lipid and anti-atherosclerosis in hyperlipemia quails].
Li C, Gao Y, Li M, Shi W, Liu Z. Li C, et al. Zhong Yao Cai. 2005 Aug;28(8):676-9. Zhong Yao Cai. 2005. PMID: 16379420 Chinese.
OBJECTIVE: To study the effect of Laminaria Japonica Polysaccharides on lowing serum lipid and anti-atherosclerosis in quails. ...RESULTS: The concentration of TC, TG, LDL in serum and index of liver decreased remarkedly, the ratio of HLD/TC increased remarka …
OBJECTIVE: To study the effect of Laminaria Japonica Polysaccharides on lowing serum lipid and anti-atherosclerosis in …
Molecular mechanism of a new Laminaria japonica polysaccharide on the suppression of macrophage foam cell formation via regulating cellular lipid metabolism and suppressing cellular inflammation.
Zha XQ, Xue L, Zhang HL, Asghar MN, Pan LH, Liu J, Luo JP. Zha XQ, et al. Mol Nutr Food Res. 2015 Oct;59(10):2008-21. doi: 10.1002/mnfr.201500113. Epub 2015 Jul 31. Mol Nutr Food Res. 2015. PMID: 26153221
SCOPE: Laminaria japonica is an important marine vegetable with great health benefits for preventing atherosclerosis. Since the foam cell formation is an important hallmark for the initiation of atherosclerosis, we examined the effect and underlying me …
SCOPE: Laminaria japonica is an important marine vegetable with great health benefits for preventing atherosclerosis. S …
The protective mechanisms of macroalgae Laminaria japonica consumption against lipid metabolism disorders in high-fat diet-induced hyperlipidemic rats.
Zhang Q, Fan XY, Guo WL, Cao YJ, Lin YC, Cheng WJ, Chen LJ, Rao PF, Ni L, Lv XC. Zhang Q, et al. Food Funct. 2020 Apr 30;11(4):3256-3270. doi: 10.1039/d0fo00065e. Food Funct. 2020. PMID: 32219261
Macroalgae Laminaria japonica (MLJ) has been reported to exhibit various biological activities including improving immunity, anti-aging, anti-tumor, anti-atherosclerosis and anti-diabetic, but the protective mechanisms of MLJ consumption against non-alcoholic …
Macroalgae Laminaria japonica (MLJ) has been reported to exhibit various biological activities including improving immunity, a …
Low molecular weight fucoidan ameliorates hindlimb ischemic injury in type 2 diabetic rats.
Wang Z, Liu T, Chen X, You H, Zhang Q, Xue J, Zheng Y, Luo D. Wang Z, et al. J Ethnopharmacol. 2018 Jan 10;210:434-442. doi: 10.1016/j.jep.2017.09.014. Epub 2017 Sep 14. J Ethnopharmacol. 2018. PMID: 28917976
ETHNOPHARMACOLOGICAL RELEVANCE: Low molecular weight fucoidan (LMWF), extracted from Laminaria japonica Areschoug, is a traditional Chinese medicine, commonly used to alleviate edema, particularly for feet with numbness and pain. ...
ETHNOPHARMACOLOGICAL RELEVANCE: Low molecular weight fucoidan (LMWF), extracted from Laminaria japonica Areschoug, is a tradit …