Lampe JN - Search Results

1

Cefadroxil Comparable to Cephalexin: Minimum Inhibitory Concentrations among Methicillin-Susceptible Staphylococcus aureus Isolates from Pediatric Musculoskeletal Infections.

Haynes AS, Prinzi A, Silveira LJ, Parker SK, Lampe JN, Kavanaugh JS, Horswill AR, Fish D. Haynes AS, et al. Among authors: lampe jn. Microbiol Spectr. 2022 Aug 31;10(4):e0103922. doi: 10.1128/spectrum.01039-22. Epub 2022 Jun 22. Microbiol Spectr. 2022. PMID: 35730963 Free PMC article.

2

Per- and polyfluoroalkyl substances (PFAS) inhibit cytochrome P450 CYP3A7 through direct coordination to the heme iron and water displacement.

Hvizdak M, Kandel SE, Work HM, Gracey EG, McCullough RL, Lampe JN. Hvizdak M, et al. Among authors: lampe jn. J Inorg Biochem. 2023 Mar;240:112120. doi: 10.1016/j.jinorgbio.2023.112120. Epub 2023 Jan 4. J Inorg Biochem. 2023. PMID: 36638633 Free PMC article.

3

HCV antiviral drugs have the potential to adversely perturb the maternal-fetal communication axis through inhibition of CYP3A7 DHEA-S oxidation.

Work HM, Hackett JC, Lampe JN. Work HM, et al. Among authors: lampe jn. Drug Metab Dispos. 2024 Jan 24:DMD-AR-2023-001434. doi: 10.1124/dmd.123.001434. Online ahead of print. Drug Metab Dispos. 2024. PMID: 38267095 Free article.

4

Correction: Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate.

Liu J, Kandel SE, Lampe JN, Scott EE. Liu J, et al. Among authors: lampe jn. J Biol Chem. 2023 Oct;299(10):105283. doi: 10.1016/j.jbc.2023.105283. Epub 2023 Sep 30. J Biol Chem. 2023. PMID: 37783037 Free PMC article. No abstract available.

5

Consideration of Nevirapine Analogs To Reduce Metabolically Linked Hepatotoxicity: A Cautionary Tale of the Deuteration Approach.

Kandel SE, Gracey EG, Lampe JN. Kandel SE, et al. Among authors: lampe jn. Chem Res Toxicol. 2023 Sep 28;36(10):1631-42. doi: 10.1021/acs.chemrestox.3c00192. Online ahead of print. Chem Res Toxicol. 2023. PMID: 37769118 Free article.

6

Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate.

Liu J, Kandel SE, Lampe JN, Scott EE. Liu J, et al. Among authors: lampe jn. J Biol Chem. 2023 Aug;299(8):104993. doi: 10.1016/j.jbc.2023.104993. Epub 2023 Jun 29. J Biol Chem. 2023. PMID: 37392852 Free PMC article.

7

Transcriptomics, metabolomics, and in-silico drug predictions for liver damage in young and aged burn victims.

Malachowska B, Yang WL, Qualman A, Muro I, Boe DM, Lampe JN, Kovacs EJ, Idrovo JP. Malachowska B, et al. Among authors: lampe jn. Commun Biol. 2023 Jun 2;6(1):597. doi: 10.1038/s42003-023-04964-2. Commun Biol. 2023. PMID: 37268765 Free PMC article.

8

Identification of Aloe-derived natural products as prospective lead scaffolds for SARS-CoV-2 main protease (M^pro) inhibitors.

Hicks EG, Kandel SE, Lampe JN. Hicks EG, et al. Among authors: lampe jn. Bioorg Med Chem Lett. 2022 Jun 15;66:128732. doi: 10.1016/j.bmcl.2022.128732. Epub 2022 Apr 12. Bioorg Med Chem Lett. 2022. PMID: 35427739 Free PMC article.

9

Pseudomonas aeruginosa cytochrome P450 CYP168A1 is a fatty acid hydroxylase that metabolizes arachidonic acid to the vasodilator 19-HETE.

Tooker BC, Kandel SE, Work HM, Lampe JN. Tooker BC, et al. Among authors: lampe jn. J Biol Chem. 2022 Mar;298(3):101629. doi: 10.1016/j.jbc.2022.101629. Epub 2022 Jan 24. J Biol Chem. 2022. PMID: 35085556 Free PMC article.

10

Characterization of fluorescent probe substrates to develop an efficient high-throughput assay for neonatal hepatic CYP3A7 inhibition screening.

Work HM, Kandel SE, Lampe JN. Work HM, et al. Among authors: lampe jn. Sci Rep. 2021 Sep 30;11(1):19443. doi: 10.1038/s41598-021-98219-x. Sci Rep. 2021. PMID: 34593846 Free PMC article.

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