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TGF-β: the master regulator of fibrosis.
Meng XM, Nikolic-Paterson DJ, Lan HY. Meng XM, et al. Among authors: lan hy. Nat Rev Nephrol. 2016 Jun;12(6):325-38. doi: 10.1038/nrneph.2016.48. Epub 2016 Apr 25. Nat Rev Nephrol. 2016. PMID: 27108839 Review.
Smad7 gene therapy ameliorates an autoimmune crescentic glomerulonephritis in mice.
Ka SM, Huang XR, Lan HY, Tsai PY, Yang SM, Shui HA, Chen A. Ka SM, et al. Among authors: lan hy. J Am Soc Nephrol. 2007 Jun;18(6):1777-88. doi: 10.1681/ASN.2006080901. Epub 2007 May 2. J Am Soc Nephrol. 2007. PMID: 17475816
Smad7 transgene attenuates peritoneal fibrosis in uremic rats treated with peritoneal dialysis.
Guo H, Leung JC, Lam MF, Chan LY, Tsang AW, Lan HY, Lai KN. Guo H, et al. Among authors: lan hy. J Am Soc Nephrol. 2007 Oct;18(10):2689-703. doi: 10.1681/ASN.2007010121. Epub 2007 Sep 12. J Am Soc Nephrol. 2007. PMID: 17855642
Smad7 as a therapeutic agent for chronic kidney diseases.
Lan HY. Lan HY. Front Biosci. 2008 May 1;13:4984-92. doi: 10.2741/3057. Front Biosci. 2008. PMID: 18508563 Review.
Treatment of established peritoneal fibrosis by gene transfer of Smad7 in a rat model of peritoneal dialysis.
Sun Y, Zhu F, Yu X, Nie J, Huang F, Li X, Luo N, Lan HY, Wang Y. Sun Y, et al. Among authors: lan hy. Am J Nephrol. 2009;30(1):84-94. doi: 10.1159/000203362. Epub 2009 Feb 18. Am J Nephrol. 2009. PMID: 19223683 Free PMC article.
Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: the role of Smad3.
Yang F, Chung AC, Huang XR, Lan HY. Yang F, et al. Among authors: lan hy. Hypertension. 2009 Oct;54(4):877-84. doi: 10.1161/HYPERTENSIONAHA.109.136531. Epub 2009 Aug 10. Hypertension. 2009. PMID: 19667256
Impaired TGF-beta signalling enhances peritoneal inflammation induced by E. coli in rats.
Wang X, Nie J, Jia Z, Feng M, Zheng Z, Chen W, Li X, Peng W, Zhang S, Sun L, Mao H, Lan HY, Yu X. Wang X, et al. Among authors: lan hy. Nephrol Dial Transplant. 2010 Feb;25(2):399-412. doi: 10.1093/ndt/gfp480. Epub 2009 Sep 16. Nephrol Dial Transplant. 2010. PMID: 19759272
Bradykinin and high glucose promote renal tubular inflammation.
Tang SC, Chan LY, Leung JC, Cheng AS, Chan KW, Lan HY, Lai KN. Tang SC, et al. Among authors: lan hy. Nephrol Dial Transplant. 2010 Mar;25(3):698-710. doi: 10.1093/ndt/gfp599. Epub 2009 Nov 18. Nephrol Dial Transplant. 2010. PMID: 19923143
Mechanism of chronic aristolochic acid nephropathy: role of Smad3.
Zhou L, Fu P, Huang XR, Liu F, Chung AC, Lai KN, Lan HY. Zhou L, et al. Among authors: lan hy. Am J Physiol Renal Physiol. 2010 Apr;298(4):F1006-17. doi: 10.1152/ajprenal.00675.2009. Epub 2010 Jan 20. Am J Physiol Renal Physiol. 2010. PMID: 20089673
Essential role for Smad3 in angiotensin II-induced tubular epithelial-mesenchymal transition.
Yang F, Huang XR, Chung AC, Hou CC, Lai KN, Lan HY. Yang F, et al. Among authors: lan hy. J Pathol. 2010 Aug;221(4):390-401. doi: 10.1002/path.2721. J Pathol. 2010. PMID: 20593491
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