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Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists.
Grommes C, Landreth GE, Heneka MT. Grommes C, et al. Among authors: landreth ge. Lancet Oncol. 2004 Jul;5(7):419-29. doi: 10.1016/S1470-2045(04)01509-8. Lancet Oncol. 2004. PMID: 15231248 Review.
ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models.
Cramer PE, Cirrito JR, Wesson DW, Lee CY, Karlo JC, Zinn AE, Casali BT, Restivo JL, Goebel WD, James MJ, Brunden KR, Wilson DA, Landreth GE. Cramer PE, et al. Among authors: landreth ge. Science. 2012 Mar 23;335(6075):1503-6. doi: 10.1126/science.1217697. Epub 2012 Feb 9. Science. 2012. PMID: 22323736 Free PMC article.
S6 phosphorylation-independent pathways regulate translation of 5'-terminal oligopyrimidine tract-containing mRNAs in differentiating hematopoietic cells.
Barth-Baus D, Stratton CA, Parrott L, Myerson H, Meyuhas O, Templeton DJ, Landreth GE, Hensold JO. Barth-Baus D, et al. Among authors: landreth ge. Nucleic Acids Res. 2002 May 1;30(9):1919-28. doi: 10.1093/nar/30.9.1919. Nucleic Acids Res. 2002. PMID: 11972328 Free PMC article.
A cell surface receptor complex for fibrillar beta-amyloid mediates microglial activation.
Bamberger ME, Harris ME, McDonald DR, Husemann J, Landreth GE. Bamberger ME, et al. Among authors: landreth ge. J Neurosci. 2003 Apr 1;23(7):2665-74. doi: 10.1523/JNEUROSCI.23-07-02665.2003. J Neurosci. 2003. PMID: 12684452 Free PMC article.
Nuclear receptors license phagocytosis by trem2+ myeloid cells in mouse models of Alzheimer's disease.
Savage JC, Jay T, Goduni E, Quigley C, Mariani MM, Malm T, Ransohoff RM, Lamb BT, Landreth GE. Savage JC, et al. Among authors: landreth ge. J Neurosci. 2015 Apr 22;35(16):6532-43. doi: 10.1523/JNEUROSCI.4586-14.2015. J Neurosci. 2015. PMID: 25904803 Free PMC article.
Loss of interleukin receptor-associated kinase 4 signaling suppresses amyloid pathology and alters microglial phenotype in a mouse model of Alzheimer's disease.
Cameron B, Tse W, Lamb R, Li X, Lamb BT, Landreth GE. Cameron B, et al. Among authors: landreth ge. J Neurosci. 2012 Oct 24;32(43):15112-23. doi: 10.1523/JNEUROSCI.1729-12.2012. J Neurosci. 2012. PMID: 23100432 Free PMC article.
Mechanisms underlying the rapid peroxisome proliferator-activated receptor-γ-mediated amyloid clearance and reversal of cognitive deficits in a murine model of Alzheimer's disease.
Mandrekar-Colucci S, Karlo JC, Landreth GE. Mandrekar-Colucci S, et al. Among authors: landreth ge. J Neurosci. 2012 Jul 25;32(30):10117-28. doi: 10.1523/JNEUROSCI.5268-11.2012. J Neurosci. 2012. PMID: 22836247 Free PMC article.
Nuclear receptors as therapeutic targets for Alzheimer's disease.
Mandrekar-Colucci S, Landreth GE. Mandrekar-Colucci S, et al. Among authors: landreth ge. Expert Opin Ther Targets. 2011 Sep;15(9):1085-97. doi: 10.1517/14728222.2011.594043. Epub 2011 Jul 1. Expert Opin Ther Targets. 2011. PMID: 21718217 Free PMC article. Review.
Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimer's disease.
Wilkinson BL, Cramer PE, Varvel NH, Reed-Geaghan E, Jiang Q, Szabo A, Herrup K, Lamb BT, Landreth GE. Wilkinson BL, et al. Among authors: landreth ge. Neurobiol Aging. 2012 Jan;33(1):197.e21-32. doi: 10.1016/j.neurobiolaging.2010.06.014. Epub 2010 Aug 8. Neurobiol Aging. 2012. PMID: 20696495 Free PMC article.
CD14 and toll-like receptors 2 and 4 are required for fibrillar A{beta}-stimulated microglial activation.
Reed-Geaghan EG, Savage JC, Hise AG, Landreth GE. Reed-Geaghan EG, et al. Among authors: landreth ge. J Neurosci. 2009 Sep 23;29(38):11982-92. doi: 10.1523/JNEUROSCI.3158-09.2009. J Neurosci. 2009. PMID: 19776284 Free PMC article.
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