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SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration.
Figley MD, Gu W, Nanson JD, Shi Y, Sasaki Y, Cunnea K, Malde AK, Jia X, Luo Z, Saikot FK, Mosaiab T, Masic V, Holt S, Hartley-Tassell L, McGuinness HY, Manik MK, Bosanac T, Landsberg MJ, Kerry PS, Mobli M, Hughes RO, Milbrandt J, Kobe B, DiAntonio A, Ve T. Figley MD, et al. Among authors: landsberg mj. Neuron. 2021 Apr 7;109(7):1118-1136.e11. doi: 10.1016/j.neuron.2021.02.009. Epub 2021 Mar 2. Neuron. 2021. PMID: 33657413
A broadly protective antibody that targets the flavivirus NS1 protein.
Modhiran N, Song H, Liu L, Bletchly C, Brillault L, Amarilla AA, Xu X, Qi J, Chai Y, Cheung STM, Traves R, Setoh YX, Bibby S, Scott CAP, Freney ME, Newton ND, Khromykh AA, Chappell KJ, Muller DA, Stacey KJ, Landsberg MJ, Shi Y, Gao GF, Young PR, Watterson D. Modhiran N, et al. Among authors: landsberg mj. Science. 2021 Jan 8;371(6525):190-194. doi: 10.1126/science.abb9425. Science. 2021. PMID: 33414219
The Nucleosome Remodeling and Deacetylase Complex Has an Asymmetric, Dynamic, and Modular Architecture.
Low JKK, Silva APG, Sharifi Tabar M, Torrado M, Webb SR, Parker BL, Sana M, Smits C, Schmidberger JW, Brillault L, Jackman MJ, Williams DC Jr, Blobel GA, Hake SB, Shepherd NE, Landsberg MJ, Mackay JP. Low JKK, et al. Among authors: landsberg mj. Cell Rep. 2020 Dec 1;33(9):108450. doi: 10.1016/j.celrep.2020.108450. Cell Rep. 2020. PMID: 33264611 Free article.
Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin.
Piper SJ, Brillault L, Rothnagel R, Croll TI, Box JK, Chassagnon I, Scherer S, Goldie KN, Jones SA, Schepers F, Hartley-Tassell L, Ve T, Busby JN, Dalziel JE, Lott JS, Hankamer B, Stahlberg H, Hurst MRH, Landsberg MJ. Piper SJ, et al. Among authors: landsberg mj. Nat Commun. 2019 Apr 26;10(1):1952. doi: 10.1038/s41467-019-09890-8. Nat Commun. 2019. PMID: 31028251 Free PMC article.
Structures of fungal and plant acetohydroxyacid synthases.
Lonhienne T, Low YS, Garcia MD, Croll T, Gao Y, Wang Q, Brillault L, Williams CM, Fraser JA, McGeary RP, West NP, Landsberg MJ, Rao Z, Schenk G, Guddat LW. Lonhienne T, et al. Among authors: landsberg mj. Nature. 2020 Oct;586(7828):317-321. doi: 10.1038/s41586-020-2514-3. Epub 2020 Jul 8. Nature. 2020. PMID: 32640464
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