Lane DP - Search Results

1

Mutant p53 interactome identifies nardilysin as a p53R273H-specific binding partner that promotes invasion.

Coffill CR, Muller PA, Oh HK, Neo SP, Hogue KA, Cheok CF, Vousden KH, Lane DP, Blackstock WP, Gunaratne J. Coffill CR, et al. Among authors: lane dp. EMBO Rep. 2012 Jun 29;13(7):638-44. doi: 10.1038/embor.2012.74. EMBO Rep. 2012. PMID: 22653443 Free PMC article.

2

Expression of RB and p53 proteins in HPV-positive and HPV-negative cervical carcinoma cell lines.

Wrede D, Tidy JA, Crook T, Lane D, Vousden KH. Wrede D, et al. Mol Carcinog. 1991;4(3):171-5. doi: 10.1002/mc.2940040302. Mol Carcinog. 1991. PMID: 1648361

3

Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form.

Gannon JV, Greaves R, Iggo R, Lane DP. Gannon JV, et al. Among authors: lane dp. EMBO J. 1990 May;9(5):1595-602. doi: 10.1002/j.1460-2075.1990.tb08279.x. EMBO J. 1990. PMID: 1691710 Free PMC article.

4

HPV-16 E7 or adenovirus E1A can overcome the growth arrest of cells immortalized with a temperature-sensitive p53.

Vousden KH, Vojtesek B, Fisher C, Lane D. Vousden KH, et al. Oncogene. 1993 Jun;8(6):1697-702. Oncogene. 1993. PMID: 8389035

5

Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms.

Stad R, Little NA, Xirodimas DP, Frenk R, van der Eb AJ, Lane DP, Saville MK, Jochemsen AG. Stad R, et al. Among authors: lane dp. EMBO Rep. 2001 Nov;2(11):1029-34. doi: 10.1093/embo-reports/kve227. Epub 2001 Oct 17. EMBO Rep. 2001. PMID: 11606419 Free PMC article.

6

Ubiquitin-independent degradation of p53 mediated by high-risk human papillomavirus protein E6.

Camus S, Menéndez S, Cheok CF, Stevenson LF, Laín S, Lane DP. Camus S, et al. Among authors: lane dp. Oncogene. 2007 Jun 14;26(28):4059-70. doi: 10.1038/sj.onc.1210188. Epub 2007 Jan 15. Oncogene. 2007. PMID: 17224909 Free PMC article.

7

The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2.

Stevenson LF, Sparks A, Allende-Vega N, Xirodimas DP, Lane DP, Saville MK. Stevenson LF, et al. Among authors: lane dp. EMBO J. 2007 Feb 21;26(4):976-86. doi: 10.1038/sj.emboj.7601567. Epub 2007 Feb 8. EMBO J. 2007. PMID: 17290220 Free PMC article.

8

p53 in health and disease.

Vousden KH, Lane DP. Vousden KH, et al. Among authors: lane dp. Nat Rev Mol Cell Biol. 2007 Apr;8(4):275-83. doi: 10.1038/nrm2147. Nat Rev Mol Cell Biol. 2007. PMID: 17380161 Review.

9

R-Roscovitine simultaneously targets both the p53 and NF-kappaB pathways and causes potentiation of apoptosis: implications in cancer therapy.

Dey A, Wong ET, Cheok CF, Tergaonkar V, Lane DP. Dey A, et al. Among authors: lane dp. Cell Death Differ. 2008 Feb;15(2):263-73. doi: 10.1038/sj.cdd.4402257. Epub 2007 Nov 2. Cell Death Differ. 2008. PMID: 17975552

10

Cyclin-dependent kinase inhibitors sensitize tumor cells to nutlin-induced apoptosis: a potent drug combination.

Cheok CF, Dey A, Lane DP. Cheok CF, et al. Among authors: lane dp. Mol Cancer Res. 2007 Nov;5(11):1133-45. doi: 10.1158/1541-7786.MCR-07-0161. Mol Cancer Res. 2007. PMID: 18025259

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