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465 results
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MDM2--arbiter of p53's destruction.
Lane DP, Hall PA. Lane DP, et al. Trends Biochem Sci. 1997 Oct;22(10):372-4. doi: 10.1016/s0968-0004(97)01119-5. Trends Biochem Sci. 1997. PMID: 9357310 Review. No abstract available.
Improving cancer therapy by non-genotoxic activation of p53.
Lain S, Lane D. Lain S, et al. Eur J Cancer. 2003 May;39(8):1053-60. doi: 10.1016/s0959-8049(03)00063-7. Eur J Cancer. 2003. PMID: 12736103 Review.
Mutant p53, EGF receptor and c-erbB-2 expression in human breast cancer.
Horak E, Smith K, Bromley L, LeJeune S, Greenall M, Lane D, Harris AL. Horak E, et al. Oncogene. 1991 Dec;6(12):2277-84. Oncogene. 1991. PMID: 1685017
Analysis of p53 expression in human tumours: an antibody raised against human p53 expressed in Escherichia coli.
Midgley CA, Fisher CJ, Bártek J, Vojtĕsek B, Lane D, Barnes DM. Midgley CA, et al. J Cell Sci. 1992 Jan;101 ( Pt 1):183-9. J Cell Sci. 1992. PMID: 1569122
Over-expression of p53 nuclear oncoprotein in colorectal adenomas.
Pignatelli M, Stamp GW, Kafiri G, Lane D, Bodmer WF. Pignatelli M, et al. Int J Cancer. 1992 Mar 12;50(5):683-8. doi: 10.1002/ijc.2910500503. Int J Cancer. 1992. PMID: 1347513
The relationship of p53 immunostaining to survival in carcinoma of the lung.
McLaren R, Kuzu I, Dunnill M, Harris A, Lane D, Gatter KC. McLaren R, et al. Br J Cancer. 1992 Oct;66(4):735-8. doi: 10.1038/bjc.1992.348. Br J Cancer. 1992. PMID: 1329907 Free PMC article.
Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53.
Blattner C, Sparks A, Lane D. Blattner C, et al. Mol Cell Biol. 1999 May;19(5):3704-13. doi: 10.1128/mcb.19.5.3704. Mol Cell Biol. 1999. PMID: 10207094 Free PMC article.
HPV-16 E7 or adenovirus E1A can overcome the growth arrest of cells immortalized with a temperature-sensitive p53.
Vousden KH, Vojtesek B, Fisher C, Lane D. Vousden KH, et al. Oncogene. 1993 Jun;8(6):1697-702. Oncogene. 1993. PMID: 8389035
MDM2 SNP309 is associated with high grade node positive breast tumours and is in linkage disequilibrium with a novel MDM2 intron 1 polymorphism.
Paulin FE, O'Neill M, McGregor G, Cassidy A, Ashfield A, Ali CW, Munro AJ, Baker L, Purdie CA, Lane DP, Thompson AM. Paulin FE, et al. Among authors: lane dp. BMC Cancer. 2008 Oct 1;8:281. doi: 10.1186/1471-2407-8-281. BMC Cancer. 2008. PMID: 18828900 Free PMC article.
Pilot screening programme for small molecule activators of p53.
Berkson RG, Hollick JJ, Westwood NJ, Woods JA, Lane DP, Lain S. Berkson RG, et al. Among authors: lane dp. Int J Cancer. 2005 Jul 10;115(5):701-10. doi: 10.1002/ijc.20968. Int J Cancer. 2005. PMID: 15729694
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