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Role of aromatic amine acetyltransferases, NAT1 and NAT2, in carcinogen-DNA adduct formation in the human urinary bladder.
Badawi AF, Hirvonen A, Bell DA, Lang NP, Kadlubar FF. Badawi AF, et al. Among authors: lang np. Cancer Res. 1995 Nov 15;55(22):5230-7. Cancer Res. 1995. PMID: 7585581
In vivo human metabolism of [2-14C]2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Lang NP, Nowell S, Malfatti MA, Kulp KS, Knize MG, Davis C, Massengill J, Williams S, MacLeod S, Dingley KH, Felton JS, Turteltaub KW. Lang NP, et al. Cancer Lett. 1999 Sep 1;143(2):135-8. doi: 10.1016/s0304-3835(99)00142-1. Cancer Lett. 1999. PMID: 10503892
DNA and protein adduct formation in the colon and blood of humans after exposure to a dietary-relevant dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Dingley KH, Curtis KD, Nowell S, Felton JS, Lang NP, Turteltaub KW. Dingley KH, et al. Among authors: lang np. Cancer Epidemiol Biomarkers Prev. 1999 Jun;8(6):507-12. Cancer Epidemiol Biomarkers Prev. 1999. PMID: 10385140
Chemoprotection against the formation of colon DNA adducts from the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the rat.
Huber WW, McDaniel LP, Kaderlik KR, Teitel CH, Lang NP, Kadlubar FF. Huber WW, et al. Among authors: lang np. Mutat Res. 1997 May 12;376(1-2):115-22. doi: 10.1016/s0027-5107(97)00033-x. Mutat Res. 1997. PMID: 9202746
Effects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: a possible mechanism of organ specificity in their carcinogenesis.
Lin D, Meyer DJ, Ketterer B, Lang NP, Kadlubar FF. Lin D, et al. Among authors: lang np. Cancer Res. 1994 Sep 15;54(18):4920-6. Cancer Res. 1994. PMID: 8069858
Macromolecular adduct formation and metabolism of heterocyclic amines in humans and rodents at low doses.
Turteltaub KW, Dingley KH, Curtis KD, Malfatti MA, Turesky RJ, Garner RC, Felton JS, Lang NP. Turteltaub KW, et al. Among authors: lang np. Cancer Lett. 1999 Sep 1;143(2):149-55. doi: 10.1016/s0304-3835(99)00116-0. Cancer Lett. 1999. PMID: 10503895
Metabolic activation of methyl-hydroxylated derivatives of 7,12-dimethylbenz[a]anthracene by human liver dehydroepiandrosterone-steroid sulfotransferase.
Chou HC, Ozawa S, Fu PP, Lang NP, Kadlubar FF. Chou HC, et al. Among authors: lang np. Carcinogenesis. 1998 Jun;19(6):1071-6. doi: 10.1093/carcin/19.6.1071. Carcinogenesis. 1998. PMID: 9667746
Metabolic activation of aromatic amines by human pancreas.
Anderson KE, Hammons GJ, Kadlubar FF, Potter JD, Kaderlik KR, Ilett KF, Minchin RF, Teitel CH, Chou HC, Martin MV, Guengerich FP, Barone GW, Lang NP, Peterson LA. Anderson KE, et al. Among authors: lang np. Carcinogenesis. 1997 May;18(5):1085-92. doi: 10.1093/carcin/18.5.1085. Carcinogenesis. 1997. PMID: 9163700
Pan-fried meat containing high levels of heterocyclic aromatic amines but low levels of polycyclic aromatic hydrocarbons induces cytochrome P4501A2 activity in humans.
Sinha R, Rothman N, Brown ED, Mark SD, Hoover RN, Caporaso NE, Levander OA, Knize MG, Lang NP, Kadlubar FF. Sinha R, et al. Among authors: lang np. Cancer Res. 1994 Dec 1;54(23):6154-9. Cancer Res. 1994. PMID: 7954461
Lower levels of urinary 2-amino-3,8-dimethylimidazo[4,5-f]-quinoxaline (MeIQx) in humans with higher CYP1A2 activity.
Sinha R, Rothman N, Mark SD, Murray S, Brown ED, Levander OA, Davies DS, Lang NP, Kadlubar FF, Hoover RN. Sinha R, et al. Among authors: lang np. Carcinogenesis. 1995 Nov;16(11):2859-61. doi: 10.1093/carcin/16.11.2859. Carcinogenesis. 1995. PMID: 7586210
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