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Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency.
Blackburn JS, Liu S, Raiser DM, Martinez SA, Feng H, Meeker ND, Gentry J, Neuberg D, Look AT, Ramaswamy S, Bernards A, Trede NS, Langenau DM. Blackburn JS, et al. Among authors: langenau dm. Leukemia. 2012 Sep;26(9):2069-78. doi: 10.1038/leu.2012.116. Epub 2012 Apr 27. Leukemia. 2012. PMID: 22538478 Free PMC article.
Single-cell transcriptional analysis of normal, aberrant, and malignant hematopoiesis in zebrafish.
Moore FE, Garcia EG, Lobbardi R, Jain E, Tang Q, Moore JC, Cortes M, Molodtsov A, Kasheta M, Luo CC, Garcia AJ, Mylvaganam R, Yoder JA, Blackburn JS, Sadreyev RI, Ceol CJ, North TE, Langenau DM. Moore FE, et al. Among authors: langenau dm. J Exp Med. 2016 May 30;213(6):979-92. doi: 10.1084/jem.20152013. Epub 2016 May 2. J Exp Med. 2016. PMID: 27139488 Free PMC article.
T Cell Immune Deficiency in zap70 Mutant Zebrafish.
Moore JC, Mulligan TS, Yordán NT, Castranova D, Pham VN, Tang Q, Lobbardi R, Anselmo A, Liwski RS, Berman JN, Sadreyev RI, Weinstein BM, Langenau DM. Moore JC, et al. Among authors: langenau dm. Mol Cell Biol. 2016 Nov 14;36(23):2868-2876. doi: 10.1128/MCB.00281-16. Print 2016 Dec 1. Mol Cell Biol. 2016. PMID: 27601584 Free PMC article.
Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing.
Tang Q, Iyer S, Lobbardi R, Moore JC, Chen H, Lareau C, Hebert C, Shaw ML, Neftel C, Suva ML, Ceol CJ, Bernards A, Aryee M, Pinello L, Drummond IA, Langenau DM. Tang Q, et al. Among authors: langenau dm. J Exp Med. 2017 Oct 2;214(10):2875-2887. doi: 10.1084/jem.20170976. Epub 2017 Sep 6. J Exp Med. 2017. PMID: 28878000 Free PMC article.
TOX Regulates Growth, DNA Repair, and Genomic Instability in T-cell Acute Lymphoblastic Leukemia.
Lobbardi R, Pinder J, Martinez-Pastor B, Theodorou M, Blackburn JS, Abraham BJ, Namiki Y, Mansour M, Abdelfattah NS, Molodtsov A, Alexe G, Toiber D, de Waard M, Jain E, Boukhali M, Lion M, Bhere D, Shah K, Gutierrez A, Stegmaier K, Silverman LB, Sadreyev RI, Asara JM, Oettinger MA, Haas W, Look AT, Young RA, Mostoslavsky R, Dellaire G, Langenau DM. Lobbardi R, et al. Among authors: langenau dm. Cancer Discov. 2017 Nov;7(11):1336-1353. doi: 10.1158/2159-8290.CD-17-0267. Epub 2017 Oct 3. Cancer Discov. 2017. PMID: 28974511 Free PMC article.
95 results