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Observation of metastable Abeta amyloid protofibrils by atomic force microscopy.
Harper JD, Wong SS, Lieber CM, Lansbury PT. Harper JD, et al. Among authors: lansbury pt. Chem Biol. 1997 Feb;4(2):119-25. doi: 10.1016/s1074-5521(97)90255-6. Chem Biol. 1997. PMID: 9190286
The chemistry of scrapie infection: implications of the 'ice 9' metaphor.
Lansbury PT Jr, Caughey B. Lansbury PT Jr, et al. Chem Biol. 1995 Jan;2(1):1-5. doi: 10.1016/1074-5521(95)90074-8. Chem Biol. 1995. PMID: 9383397 Review.
Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct.
Conway KA, Rochet JC, Bieganski RM, Lansbury PT Jr. Conway KA, et al. Among authors: lansbury pt jr. Science. 2001 Nov 9;294(5545):1346-9. doi: 10.1126/science.1063522. Science. 2001. PMID: 11701929
Neurodegeneration: new clues on inclusions.
Lansbury PT Jr, Kosik KS. Lansbury PT Jr, et al. Chem Biol. 2000 Jan;7(1):R9-R12. doi: 10.1016/s1074-5521(00)00068-5. Chem Biol. 2000. PMID: 10662685 Review.
Amyloid probes based on Congo Red distinguish between fibrils comprising different peptides.
Ashburn TT, Han H, McGuinness BF, Lansbury PT Jr. Ashburn TT, et al. Among authors: lansbury pt jr. Chem Biol. 1996 May;3(5):351-8. doi: 10.1016/s1074-5521(96)90118-0. Chem Biol. 1996. PMID: 8807864
NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded.
Weinreb PH, Zhen W, Poon AW, Conway KA, Lansbury PT Jr. Weinreb PH, et al. Among authors: lansbury pt jr. Biochemistry. 1996 Oct 29;35(43):13709-15. doi: 10.1021/bi961799n. Biochemistry. 1996. PMID: 8901511
Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid.
Conway KA, Harper JD, Lansbury PT Jr. Conway KA, et al. Among authors: lansbury pt jr. Biochemistry. 2000 Mar 14;39(10):2552-63. doi: 10.1021/bi991447r. Biochemistry. 2000. PMID: 10704204
The core Alzheimer's peptide NAC forms amyloid fibrils which seed and are seeded by beta-amyloid: is NAC a common trigger or target in neurodegenerative disease?
Han H, Weinreb PH, Lansbury PT Jr. Han H, et al. Among authors: lansbury pt jr. Chem Biol. 1995 Mar;2(3):163-9. doi: 10.1016/1074-5521(95)90071-3. Chem Biol. 1995. PMID: 9383418
Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins.
Harper JD, Lansbury PT Jr. Harper JD, et al. Among authors: lansbury pt jr. Annu Rev Biochem. 1997;66:385-407. doi: 10.1146/annurev.biochem.66.1.385. Annu Rev Biochem. 1997. PMID: 9242912 Review.
Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?
Jarrett JT, Lansbury PT Jr. Jarrett JT, et al. Among authors: lansbury pt jr. Cell. 1993 Jun 18;73(6):1055-8. doi: 10.1016/0092-8674(93)90635-4. Cell. 1993. PMID: 8513491 Review. No abstract available.
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