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1992 1
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56 results

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Page 1
Twenty-four-hour monitoring of intragastric acidity: comparison between lansoprazole 30mg and pantoprazole 40mg.
Florent C, Forestier S. Florent C, et al. Eur J Gastroenterol Hepatol. 1997 Feb;9(2):195-200. doi: 10.1097/00042737-199702000-00017. Eur J Gastroenterol Hepatol. 1997. PMID: 9058634 Clinical Trial.
DESIGN: Twelve healthy volunteers were included in an open, randomized, crossover study. Each subject received lansoprazole 30mg during 7 days followed, after a 14-day wash-out period, by pantoprazole 40 mg for 7 days or vice versa. ...Significant differences in aci …
DESIGN: Twelve healthy volunteers were included in an open, randomized, crossover study. Each subject received lansoprazole 30mg …
Evidence for therapeutic equivalence of lansoprazole 30mg and esomeprazole 40mg in the treatment of erosive oesophagitis.
Howden CW, Ballard ED 2nd, Robieson W. Howden CW, et al. Clin Drug Investig. 2002;22(2):99-109. doi: 10.2165/00044011-200222020-00004. Clin Drug Investig. 2002. PMID: 23315397
OBJECTIVE: To compare the effectiveness of lansoprazole 30mg once daily and esomeprazole 40mg once daily on healing and symptom relief in patients with erosive oesophagitis. ...CONCLUSIONS: In erosive oesophagitis, lansoprazole 30mg once daily and esom …
OBJECTIVE: To compare the effectiveness of lansoprazole 30mg once daily and esomeprazole 40mg once daily on healing and sympto …
Lansoprazole for maintenance of remission of erosive oesophagitis.
Freston JW, Jackson RL, Huang B, Ballard ED 2nd. Freston JW, et al. Drugs. 2002;62(8):1173-84. doi: 10.2165/00003495-200262080-00004. Drugs. 2002. PMID: 12010078 Review.
Among those with erosive oesophagitis, maintenance therapy with lansoprazole 15 or 30mg once daily is highly effective in preventing relapse. Studies have documented that lansoprazole 15 and 30mg once daily for six months prevents oesophagitis relapse …
Among those with erosive oesophagitis, maintenance therapy with lansoprazole 15 or 30mg once daily is highly effective in prev …
Esomeprazole: a review of its use in the management of acid-related disorders.
Scott LJ, Dunn CJ, Mallarkey G, Sharpe M. Scott LJ, et al. Drugs. 2002;62(10):1503-38. doi: 10.2165/00003495-200262100-00006. Drugs. 2002. PMID: 12093317 Review.
In a large well designed 8-week trial in patients (n >5000) with erosive oesophagitis, esomeprazole recipients achieved significantly higher rates of endoscopically confirmed healed oesophagitis than those receiving lansoprazole. Respective healed oesophagitis rates wit …
In a large well designed 8-week trial in patients (n >5000) with erosive oesophagitis, esomeprazole recipients achieved significantly hig …
Pharmacokinetics and absolute bioavailability of lansoprazole.
Gerloff J, Mignot A, Barth H, Heintze K. Gerloff J, et al. Eur J Clin Pharmacol. 1996;50(4):293-7. doi: 10.1007/s002280050111. Eur J Clin Pharmacol. 1996. PMID: 8803522 Clinical Trial.
OBJECTIVE: In a crossover study 12 healthy volunteers received lansoprazole 15 mg or 30 mg orally, or 15 mg intravenously in randomized order as a single dose. Blood samples were taken and plasma levels of lansoprazole were determined using an HPLC method. The volun …
OBJECTIVE: In a crossover study 12 healthy volunteers received lansoprazole 15 mg or 30 mg orally, or 15 mg intravenously in randomiz …
Comparison of the pharmacokinetics of lansoprazole 15- and 30-mg sachets for suspension versus intact capsules.
Amer F, Karol MD, Pan WJ, Griffin JS, Lukasik NL, Locke CS, Chiu YL. Amer F, et al. Clin Ther. 2004 Dec;26(12):2076-83. doi: 10.1016/j.clinthera.2004.12.008. Clin Ther. 2004. PMID: 15823771 Clinical Trial.
OBJECTIVE: The pharmacokinetic profiles of single doses of lansoprazole 15- and 30-mg sachets for suspension were compared with those of corresponding doses of lansoprazole oral capsules. ...In the first study, each subject received 1 lansoprazole 15-mg sache …
OBJECTIVE: The pharmacokinetic profiles of single doses of lansoprazole 15- and 30-mg sachets for suspension were compared with those …
Pharmacokinetic properties of lansoprazole (30-mg enteric-coated capsules) and its metabolites: A single-dose, open-label study in healthy Chinese male subjects.
Song M, Gao X, Hang TJ, Wen AD. Song M, et al. Curr Ther Res Clin Exp. 2009 Jun;70(3):228-39. doi: 10.1016/j.curtheres.2009.05.002. Curr Ther Res Clin Exp. 2009. PMID: 24683233 Free PMC article.
It is metabolized mainly in the liver, and its primary active metabolites present in plasma are 5'-hydroxy lansoprazole and lansoprazole sulfone. Few data are available on the pharmacokinetic properties of lansoprazole, 5'-hydroxy lansoprazole, and …
It is metabolized mainly in the liver, and its primary active metabolites present in plasma are 5'-hydroxy lansoprazole and lansop …
The effects of lansoprazole, a new H+,K(+)-ATPase inhibitor, on gastric pH and serum gastrin.
Sanders SW, Tolman KG, Greski PA, Jennings DE, Hoyos PA, Page JG. Sanders SW, et al. Aliment Pharmacol Ther. 1992 Jun;6(3):359-72. doi: 10.1111/j.1365-2036.1992.tb00057.x. Aliment Pharmacol Ther. 1992. PMID: 1600052 Clinical Trial.
This study examined the effects of dose and time of administration of lansoprazole on gastric pH and serum gastrin in healthy male volunteers. Three groups of six subjects received 10, 20 or 60 mg doses of lansoprazole or placebo. ...An additional 18 subjects receiv …
This study examined the effects of dose and time of administration of lansoprazole on gastric pH and serum gastrin in healthy male vo …
Simplified lansoprazole suspension--a liquid formulation of lansoprazole--effectively suppresses intragastric acidity when administered through a gastrostomy.
Sharma VK, Vasudeva R, Howden CW. Sharma VK, et al. Am J Gastroenterol. 1999 Jul;94(7):1813-7. doi: 10.1111/j.1572-0241.1999.01210.x. Am J Gastroenterol. 1999. PMID: 10406240 Clinical Trial.
OBJECTIVE: Lansoprazole suppresses intragastric acidity when given as nonencapsulated intact granules. ...Corresponding values after lansoprazole granules in orange juice were 77.5%, 67%, and 49.6% (p < 0.01 for each comparison with baseline). ...
OBJECTIVE: Lansoprazole suppresses intragastric acidity when given as nonencapsulated intact granules. ...Corresponding values after …
Effective maintenance treatment of reflux esophagitis with low-dose lansoprazole. A randomized, double-blind, placebo-controlled trial.
Robinson M, Lanza F, Avner D, Haber M. Robinson M, et al. Ann Intern Med. 1996 May 15;124(10):859-67. doi: 10.7326/0003-4819-124-10-199605150-00001. Ann Intern Med. 1996. PMID: 8610914 Clinical Trial.
By month 1, 45% of placebo recipients remained healed compared with more than 90% of patients in either lansoprazole group. By month 12, only 24% of placebo recipients remained healed compared with 79% of patients receiving 15 mg of lansoprazole and 90% of patients …
By month 1, 45% of placebo recipients remained healed compared with more than 90% of patients in either lansoprazole group. By month …
56 results