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Immunology. Licence to kill.
Lanzavecchia A. Lanzavecchia A. Nature. 1998 Jun 4;393(6684):413-4. doi: 10.1038/30845. Nature. 1998. PMID: 9623994 No abstract available.
Memory in disguise.
Sallusto F, Lanzavecchia A. Sallusto F, et al. Nat Med. 2011 Oct 11;17(10):1182-3. doi: 10.1038/nm.2502. Nat Med. 2011. PMID: 21988989 No abstract available.
Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization.
Cella M, Facchetti F, Lanzavecchia A, Colonna M. Cella M, et al. Nat Immunol. 2000 Oct;1(4):305-10. doi: 10.1038/79747. Nat Immunol. 2000. PMID: 11017101
Plasmacytoid dendritic cells (PDCs) are a subset of dendritic cells present in human blood and inflamed lymph nodes. Here we show that blood PDCs, when stimulated with influenza virus and CD40L in vitro, undergo a maturation process characterized by up-regulation of …
Plasmacytoid dendritic cells (PDCs) are a subset of dendritic cells present in human blood and inflamed lymph nodes. Here we show tha …
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions.
Sallusto F, Lenig D, Förster R, Lipp M, Lanzavecchia A. Sallusto F, et al. Nature. 1999 Oct 14;401(6754):708-12. doi: 10.1038/44385. Nature. 1999. PMID: 10537110
A fraction of primed T lymphocytes persists as circulating memory cells that can confer protection and give, upon secondary challenge, a qualitatively different and quantitatively enhanced response. ...The CCR7+ and CCR7- T cells, which we have named central memory
A fraction of primed T lymphocytes persists as circulating memory cells that can confer protection and give, upon secondary challenge
Peptide partners call the tune.
Lanzavecchia A, Watts C. Lanzavecchia A, et al. Nature. 1994 Sep 15;371(6494):198-9. doi: 10.1038/371198a0. Nature. 1994. PMID: 8078577 No abstract available.
Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells.
Cella M, Engering A, Pinet V, Pieters J, Lanzavecchia A. Cella M, et al. Nature. 1997 Aug 21;388(6644):782-7. doi: 10.1038/42030. Nature. 1997. PMID: 9285591
To do so they must not only capture antigens with high efficiency and broad specificity, but must also maximize their capacity to load class II molecules of the major histocompatibility complex (MHC) with antigenic peptides in order to present a large array of epitopes fro …
To do so they must not only capture antigens with high efficiency and broad specificity, but must also maximize their capacity to load class …
Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon.
Cella M, Jarrossay D, Facchetti F, Alebardi O, Nakajima H, Lanzavecchia A, Colonna M. Cella M, et al. Nat Med. 1999 Aug;5(8):919-23. doi: 10.1038/11360. Nat Med. 1999. PMID: 10426316
These results, with the distinct cell phenotype, indicate that plasmacytoid monocytes represent a specialized cell lineage that enters inflamed lymph nodes at high endothelial venules, where it produces type I interferon. ...
These results, with the distinct cell phenotype, indicate that plasmacytoid monocytes represent a specialized cell lineage that enter …
Antigen decoding by T lymphocytes: from synapses to fate determination.
Lanzavecchia A, Sallusto F. Lanzavecchia A, et al. Nat Immunol. 2001 Jun;2(6):487-92. doi: 10.1038/88678. Nat Immunol. 2001. PMID: 11376334 Review.
At the immunological synapse between the T cell and a DC, T cell receptors (TCRs) are serially engaged and triggered by specific ligands. ...
At the immunological synapse between the T cell and a DC, T cell receptors (TCRs) are serially engaged and triggered by specific liga …
Antigen-specific interaction between T and B cells.
Lanzavecchia A. Lanzavecchia A. Nature. 1985 Apr 11-17;314(6011):537-9. doi: 10.1038/314537a0. Nature. 1985. PMID: 3157869
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