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Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses.
Sallusto F, Lanzavecchia A, Mackay CR. Sallusto F, et al. Immunol Today. 1998 Dec;19(12):568-74. doi: 10.1016/s0167-5699(98)01346-2. Immunol Today. 1998. PMID: 9864948 Review. No abstract available.
Human B cell memory.
Lanzavecchia A, Sallusto F. Lanzavecchia A, et al. Curr Opin Immunol. 2009 Jun;21(3):298-304. doi: 10.1016/j.coi.2009.05.019. Epub 2009 Jun 6. Curr Opin Immunol. 2009. PMID: 19497721 Free PMC article. Review.
Cholera toxin induces maturation of human dendritic cells and licences them for Th2 priming.
Gagliardi MC, Sallusto F, Marinaro M, Langenkamp A, Lanzavecchia A, De Magistris MT. Gagliardi MC, et al. Eur J Immunol. 2000 Aug;30(8):2394-403. doi: 10.1002/1521-4141(2000)30:8<2394::AID-IMMU2394>3.0.CO;2-Y. Eur J Immunol. 2000. PMID: 10940931
Cholera toxin (CT) is a potent mucosal adjuvant that amplifies B and T cell responses to mucosally co-administered antigens, stimulating predominant Th2-type responses. ...Our results help to elucidate the mechanism of action of CT as an adjuvant and highlight a new …
Cholera toxin (CT) is a potent mucosal adjuvant that amplifies B and T cell responses to mucosally co-administered antigens, stimulat …
Mouse pre-immunocytes as non-proliferating multipotent precursors of macrophages, interferon-producing cells, CD8alpha(+) and CD8alpha(-) dendritic cells.
Bruno L, Seidl T, Lanzavecchia A. Bruno L, et al. Eur J Immunol. 2001 Nov;31(11):3403-12. doi: 10.1002/1521-4141(200111)31:11<3403::aid-immu3403>3.0.co;2-t. Eur J Immunol. 2001. PMID: 11745359
In this study we characterize in mouse bone marrow and peripheral blood a homogeneous cell subset expressing Ly6C, CD31 and CD11c, that can give rise to multiple cell types involved in the immune response. ...These cells are defined as "pre-immunocytes" to underline the fa …
In this study we characterize in mouse bone marrow and peripheral blood a homogeneous cell subset expressing Ly6C, CD31 and CD11c, th …
Three signals and a master switch in the regulation of T-cell immunity.
Lanzavecchia A. Lanzavecchia A. Cold Spring Harb Symp Quant Biol. 1999;64:253-7. doi: 10.1101/sqb.1999.64.253. Cold Spring Harb Symp Quant Biol. 1999. PMID: 11232293 Review. No abstract available.
Functional subsets of memory T cells identified by CCR7 expression.
Sallusto F, Langenkamp A, Geginat J, Lanzavecchia A. Sallusto F, et al. Curr Top Microbiol Immunol. 2000;251:167-71. doi: 10.1007/978-3-642-57276-0_21. Curr Top Microbiol Immunol. 2000. PMID: 11036772 No abstract available.
Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization.
Cella M, Facchetti F, Lanzavecchia A, Colonna M. Cella M, et al. Nat Immunol. 2000 Oct;1(4):305-10. doi: 10.1038/79747. Nat Immunol. 2000. PMID: 11017101
Plasmacytoid dendritic cells (PDCs) are a subset of dendritic cells present in human blood and inflamed lymph nodes. Here we show that blood PDCs, when stimulated with influenza virus and CD40L in vitro, undergo a maturation process characterized by up-regulation of …
Plasmacytoid dendritic cells (PDCs) are a subset of dendritic cells present in human blood and inflamed lymph nodes. Here we show tha …
The role of chemokine receptors in primary, effector, and memory immune responses.
Sallusto F, Mackay CR, Lanzavecchia A. Sallusto F, et al. Annu Rev Immunol. 2000;18:593-620. doi: 10.1146/annurev.immunol.18.1.593. Annu Rev Immunol. 2000. PMID: 10837070 Review.
The immune system is composed of single cells, and its function is entirely dependent on the capacity of these cells to traffic, localize within tissues, and interact with each other in a precisely coordinated fashion. There is growing evidence that the large families of c …
The immune system is composed of single cells, and its function is entirely dependent on the capacity of these cells to traffic, localize wi …
Dendritic cell maturation is induced by mycoplasma infection but not by necrotic cells.
Salio M, Cerundolo V, Lanzavecchia A. Salio M, et al. Eur J Immunol. 2000 Feb;30(2):705-8. doi: 10.1002/1521-4141(200002)30:2<705::AID-IMMU705>3.0.CO;2-P. Eur J Immunol. 2000. PMID: 10671230
The interplay between the duration of TCR and cytokine signaling determines T cell polarization.
Iezzi G, Scotet E, Scheidegger D, Lanzavecchia A. Iezzi G, et al. Eur J Immunol. 1999 Dec;29(12):4092-101. doi: 10.1002/(SICI)1521-4141(199912)29:12<4092::AID-IMMU4092>3.0.CO;2-A. Eur J Immunol. 1999. PMID: 10602020
In contrast, Th2 polarization requires a prolonged TCR stimulation and IL-4 is effective only when present during the period of TCR triggering. ...Thus, the duration of TCR stimulation represents a crucial parameter that influences the response to polarizing cytokin …
In contrast, Th2 polarization requires a prolonged TCR stimulation and IL-4 is effective only when present during the period of TCR t …
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