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Endotoxins, asthma, and allergic immune responses.
Lapa e Silva JR, Possebon da Silva MD, Lefort J, Vargaftig BB. Lapa e Silva JR, et al. Toxicology. 2000 Nov 2;152(1-3):31-5. doi: 10.1016/s0300-483x(00)00289-4. Toxicology. 2000. PMID: 11090937 Review.
Protective effects of phosphodiesterase inhibitors on lung function and remodeling in a murine model of chronic asthma.
Campos HS, Xisto DG, Oliveira MB, Teixeira I, Negri EM, Mauad T, Carnielli D, Lima LM, Barreiro EJ, Faffe DS, Zin WA, Lapa e Silva JR, Rocco PR. Campos HS, et al. Among authors: lapa e silva jr. Braz J Med Biol Res. 2006 Feb;39(2):283-7. doi: 10.1590/s0100-879x2006000200016. Epub 2006 Feb 2. Braz J Med Biol Res. 2006. PMID: 16470317
Lung parenchyma remodeling in a murine model of chronic allergic inflammation.
Xisto DG, Farias LL, Ferreira HC, Picanço MR, Amitrano D, Lapa E Silva JR, Negri EM, Mauad T, Carnielli D, Silva LF, Capelozzi VL, Faffe DS, Zin WA, Rocco PR. Xisto DG, et al. Among authors: lapa e silva jr, silva lf. Am J Respir Crit Care Med. 2005 Apr 15;171(8):829-37. doi: 10.1164/rccm.200408-997OC. Epub 2005 Jan 18. Am J Respir Crit Care Med. 2005. PMID: 15657464
Tuberculosis is associated with a down-modulatory lung immune response that impairs Th1-type immunity.
Almeida AS, Lago PM, Boechat N, Huard RC, Lazzarini LC, Santos AR, Nociari M, Zhu H, Perez-Sweeney BM, Bang H, Ni Q, Huang J, Gibson AL, Flores VC, Pecanha LR, Kritski AL, Lapa e Silva JR, Ho JL. Almeida AS, et al. Among authors: lapa e silva jr. J Immunol. 2009 Jul 1;183(1):718-31. doi: 10.4049/jimmunol.0801212. Epub 2009 Jun 17. J Immunol. 2009. PMID: 19535630
Cellular and biochemical bases of chronic obstructive pulmonary disease.
Rufino R, Lapa e Silva JR. Rufino R, et al. Among authors: lapa e silva jr. J Bras Pneumol. 2006 May-Jun;32(3):241-8. J Bras Pneumol. 2006. PMID: 17273614 Review. English, Portuguese.
Immunoglobulin A (IgA) and IgG immune responses against P-90 antigen for diagnosis of pulmonary tuberculosis and screening for Mycobacterium tuberculosis infection.
Conde MB, Suffys P, Lapa E Silva JR, Kritski AL, Dorman SE. Conde MB, et al. Among authors: lapa e silva jr. Clin Diagn Lab Immunol. 2004 Jan;11(1):94-7. doi: 10.1128/cdli.11.1.94-97.2004. Clin Diagn Lab Immunol. 2004. PMID: 14715551 Free PMC article.
Small bowel of patients with asthma and allergic rhinitis: absence of inflammation despite the presence of major cellular components of allergic inflammation.
Pires GV, Souza HS, Elia CC, Zaltman C, Carvalho AT, Tortori CJ, Garrofé HC, Lapa e Silva JR. Pires GV, et al. Among authors: lapa e silva jr. Allergy Asthma Proc. 2004 Jul-Aug;25(4):253-9. Allergy Asthma Proc. 2004. PMID: 15510586
Impact of Bacillus Calmette-Guérin Moreau vaccine on lung remodeling in experimental asthma.
Samary Cdos S, Antunes MA, Silva JD, Silva AL, Araújo CC, Bakker-Abreu I, Diaz BL, Fernezlian S, Parra ER, Capelozzi VL, Silva PL, Lapa e Silva JR, Rocco PR. Samary Cdos S, et al. Among authors: silva jd, silva al, silva pl, lapa e silva jr. Respir Physiol Neurobiol. 2013 Dec 1;189(3):614-23. doi: 10.1016/j.resp.2013.07.025. Epub 2013 Aug 6. Respir Physiol Neurobiol. 2013. PMID: 23928268 Clinical Trial.
Prevention of antigen-induced bronchial hyperreactivity and airway inflammation in sensitized guinea-pigs by tacrolimus.
Lapa e Silva JR, Ruffié C, Lefort J, Nahori MA, Vargaftig BB, Pretolani M. Lapa e Silva JR, et al. Mediators Inflamm. 1999;8(1):17-23. doi: 10.1080/09629359990676. Mediators Inflamm. 1999. PMID: 10704085 Free PMC article.
Modulation of the bronchial inflammation in sensitized guinea-pigs by FK506, nedocromil sodium and dexamethasone.
Lapa e Silva JR, Ruffié C, Vargaftig BB, Pretolani M. Lapa e Silva JR, et al. Eur Respir J. 1995 Aug;8(8):1321-7. doi: 10.1183/09031936.95.08081321. Eur Respir J. 1995. PMID: 7489798
On the day of the experiment, i.e. one week after the booster injection of antigen, the animals were killed, the lungs dissected, frozen and cryostat sections stained by immunohistochemical methods using monoclonal antibodies specific for total T-lymphocytes, CD4+ and CD8+ …
On the day of the experiment, i.e. one week after the booster injection of antigen, the animals were killed, the lungs dissected, fro …
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