Lapenson DP - Search Results

1

Human liver microsomal steroid metabolism: identification of the major microsomal steroid hormone 6 beta-hydroxylase cytochrome P-450 enzyme.

Waxman DJ, Attisano C, Guengerich FP, Lapenson DP. Waxman DJ, et al. Among authors: lapenson dp. Arch Biochem Biophys. 1988 Jun;263(2):424-36. doi: 10.1016/0003-9861(88)90655-8. Arch Biochem Biophys. 1988. PMID: 3259858

2

Monoclonal antibodies to rat liver cytochrome P-450 2c/RLM5 that regiospecifically inhibit steroid metabolism.

Park SS, Waxman DJ, Lapenson DP, Schenkman JB, Gelboin HV. Park SS, et al. Among authors: lapenson dp. Biochem Pharmacol. 1989 Sep 15;38(18):3067-74. doi: 10.1016/0006-2952(89)90017-8. Biochem Pharmacol. 1989. PMID: 2783161

3

Sequence requirements for cytochrome P-450IIB1 catalytic activity. Alteration of the stereospecificity and regioselectivity of steroid hydroxylation by a simultaneous change of two hydrophobic amino acid residues to phenylalanine.

Aoyama T, Korzekwa K, Nagata K, Adesnik M, Reiss A, Lapenson DP, Gillette J, Gelboin HV, Waxman DJ, Gonzalez FJ. Aoyama T, et al. Among authors: lapenson dp. J Biol Chem. 1989 Dec 15;264(35):21327-33. J Biol Chem. 1989. PMID: 2574176 Free article.

4

Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine.

Aoyama T, Yamano S, Waxman DJ, Lapenson DP, Meyer UA, Fischer V, Tyndale R, Inaba T, Kalow W, Gelboin HV, et al. Aoyama T, et al. Among authors: lapenson dp. J Biol Chem. 1989 Jun 25;264(18):10388-95. J Biol Chem. 1989. PMID: 2732228

5

Gene conversion and differential regulation in the rat P-450 IIA gene subfamily. Purification, catalytic activity, cDNA and deduced amino acid sequence, and regulation of an adult male-specific hepatic testosterone 15 alpha-hydroxylase.

Matsunaga T, Nagata K, Holsztynska EJ, Lapenson DP, Smith A, Kato R, Gelboin HV, Waxman DJ, Gonzalez FJ. Matsunaga T, et al. Among authors: lapenson dp. J Biol Chem. 1988 Dec 5;263(34):17995-8002. J Biol Chem. 1988. PMID: 3192524

6

Monoclonal antibodies inhibitory to rat hepatic cytochromes P-450: P-450 form specificities and use as probes for cytochrome P-450-dependent steroid hydroxylations.

Waxman DJ, Lapenson DP, Park SS, Attisano C, Gelboin HV. Waxman DJ, et al. Among authors: lapenson dp. Mol Pharmacol. 1987 Nov;32(5):615-24. Mol Pharmacol. 1987. PMID: 3119986

7

Antibodies to liver/kidney microsome1 in chronic active hepatitis recognize specific forms of hepatic cytochrome P-450.

Waxman DJ, Lapenson DP, Krishnan M, Bernard O, Kreibich G, Alvarez F. Waxman DJ, et al. Among authors: lapenson dp. Gastroenterology. 1988 Nov;95(5):1326-31. doi: 10.1016/0016-5085(88)90368-x. Gastroenterology. 1988. PMID: 3049217

8

Androgen hydroxylation catalysed by a cell line (SD1) that stably expresses rat hepatic cytochrome P-450 PB-4 (IIB1).

Waxman DJ, Lapenson DP, Morrissey JJ, Park SS, Gelboin HV, Doehmer J, Oesch F. Waxman DJ, et al. Among authors: lapenson dp. Biochem J. 1989 May 15;260(1):81-5. doi: 10.1042/bj2600081. Biochem J. 1989. PMID: 2789039 Free PMC article.

9

Participation of two structurally related enzymes in rat hepatic microsomal androstenedione 7 alpha-hydroxylation.

Waxman DJ, Lapenson DP, Nagata K, Conlon HD. Waxman DJ, et al. Among authors: lapenson dp. Biochem J. 1990 Jan 1;265(1):187-94. doi: 10.1042/bj2650187. Biochem J. 1990. PMID: 2302165 Free PMC article.

10

Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s.

Waxman DJ, Lapenson DP, Aoyama T, Gelboin HV, Gonzalez FJ, Korzekwa K. Waxman DJ, et al. Among authors: lapenson dp. Arch Biochem Biophys. 1991 Oct;290(1):160-6. doi: 10.1016/0003-9861(91)90602-f. Arch Biochem Biophys. 1991. PMID: 1898086

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