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The Signal Transducer and Activator of Transcription 1 (STAT1) Inhibits Mitochondrial Biogenesis in Liver and Fatty Acid Oxidation in Adipocytes.
Sisler JD, Morgan M, Raje V, Grande RC, Derecka M, Meier J, Cantwell M, Szczepanek K, Korzun WJ, Lesnefsky EJ, Harris TE, Croniger CM, Larner AC. Sisler JD, et al. Among authors: larner ac. PLoS One. 2015 Dec 21;10(12):e0144444. doi: 10.1371/journal.pone.0144444. eCollection 2015. PLoS One. 2015. PMID: 26689548 Free PMC article.
Mitochondrial-targeted Signal transducer and activator of transcription 3 (STAT3) protects against ischemia-induced changes in the electron transport chain and the generation of reactive oxygen species.
Szczepanek K, Chen Q, Derecka M, Salloum FN, Zhang Q, Szelag M, Cichy J, Kukreja RC, Dulak J, Lesnefsky EJ, Larner AC. Szczepanek K, et al. Among authors: larner ac. J Biol Chem. 2011 Aug 26;286(34):29610-20. doi: 10.1074/jbc.M111.226209. Epub 2011 Jun 29. J Biol Chem. 2011. PMID: 21715323 Free PMC article.
Function of mitochondrial Stat3 in cellular respiration.
Wegrzyn J, Potla R, Chwae YJ, Sepuri NB, Zhang Q, Koeck T, Derecka M, Szczepanek K, Szelag M, Gornicka A, Moh A, Moghaddas S, Chen Q, Bobbili S, Cichy J, Dulak J, Baker DP, Wolfman A, Stuehr D, Hassan MO, Fu XY, Avadhani N, Drake JI, Fawcett P, Lesnefsky EJ, Larner AC. Wegrzyn J, et al. Among authors: larner ac. Science. 2009 Feb 6;323(5915):793-7. doi: 10.1126/science.1164551. Epub 2009 Jan 8. Science. 2009. PMID: 19131594 Free PMC article.
Tyk2 and Stat3 regulate brown adipose tissue differentiation and obesity.
Derecka M, Gornicka A, Koralov SB, Szczepanek K, Morgan M, Raje V, Sisler J, Zhang Q, Otero D, Cichy J, Rajewsky K, Shimoda K, Poli V, Strobl B, Pellegrini S, Harris TE, Seale P, Russell AP, McAinch AJ, O'Brien PE, Keller SR, Croniger CM, Kordula T, Larner AC. Derecka M, et al. Among authors: larner ac. Cell Metab. 2012 Dec 5;16(6):814-24. doi: 10.1016/j.cmet.2012.11.005. Cell Metab. 2012. PMID: 23217260 Free PMC article.
91 results