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Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes.
Grarup N, Moltke I, Andersen MK, Dalby M, Vitting-Seerup K, Kern T, Mahendran Y, Jørsboe E, Larsen CVL, Dahl-Petersen IK, Gilly A, Suveges D, Dedoussis G, Zeggini E, Pedersen O, Andersson R, Bjerregaard P, Jørgensen ME, Albrechtsen A, Hansen T. Grarup N, et al. Among authors: larsen cvl. Nat Genet. 2018 Feb;50(2):172-174. doi: 10.1038/s41588-017-0022-7. Epub 2018 Jan 8. Nat Genet. 2018. PMID: 29311636 Free PMC article.
Associations between vitamin D status and atherosclerosis among Inuit in Greenland.
Gjødesen CU, Jørgensen ME, Bjerregaard P, Dahl-Petersen IK, Larsen CVL, Noël M, Melbye M, Cohen AS, Lundqvist M, Hougaard DM, Helge JW, Nielsen NO. Gjødesen CU, et al. Among authors: larsen cvl. Atherosclerosis. 2018 Jan;268:145-151. doi: 10.1016/j.atherosclerosis.2017.11.028. Epub 2017 Dec 1. Atherosclerosis. 2018. PMID: 29227867
Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population.
Grarup N, Moltke I, Andersen MK, Bjerregaard P, Larsen CVL, Dahl-Petersen IK, Jørsboe E, Tiwari HK, Hopkins SE, Wiener HW, Boyer BB, Linneberg A, Pedersen O, Jørgensen ME, Albrechtsen A, Hansen T. Grarup N, et al. Among authors: larsen cvl. Diabetologia. 2018 Sep;61(9):2005-2015. doi: 10.1007/s00125-018-4659-2. Epub 2018 Jun 20. Diabetologia. 2018. PMID: 29926116 Free PMC article.
The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders.
Andersen MK, Jørsboe E, Skotte L, Hanghøj K, Sandholt CH, Moltke I, Grarup N, Kern T, Mahendran Y, Søborg B, Bjerregaard P, Larsen CVL, Dahl-Petersen IK, Tiwari HK, Feenstra B, Koch A, Wiener HW, Hopkins SE, Pedersen O, Melbye M, Boyer BB, Jørgensen ME, Albrechtsen A, Hansen T. Andersen MK, et al. Among authors: larsen cvl. PLoS Genet. 2020 Jan 24;16(1):e1008544. doi: 10.1371/journal.pgen.1008544. eCollection 2020 Jan. PLoS Genet. 2020. PMID: 31978080 Free PMC article.
The genetic history of Greenlandic-European contact.
Waples RK, Hauptmann AL, Seiding I, Jørsboe E, Jørgensen ME, Grarup N, Andersen MK, Larsen CVL, Bjerregaard P, Hellenthal G, Hansen T, Albrechtsen A, Moltke I. Waples RK, et al. Among authors: larsen cvl. Curr Biol. 2021 May 24;31(10):2214-2219.e4. doi: 10.1016/j.cub.2021.02.041. Epub 2021 Mar 11. Curr Biol. 2021. PMID: 33711251 Free PMC article.
Loss of Sucrase-Isomaltase Function Increases Acetate Levels and Improves Metabolic Health in Greenlandic Cohorts.
Andersen MK, Skotte L, Jørsboe E, Polito R, Stæger FF, Aldiss P, Hanghøj K, Waples RK, Santander CG, Grarup N, Dahl-Petersen IK, Diaz LJ, Overvad M, Senftleber NK, Søborg B, Larsen CVL, Lemoine C, Pedersen O, Feenstra B, Bjerregaard P, Melbye M, Jørgensen ME, Færgeman NJ, Koch A, Moritz T, Gillum MP, Moltke I, Hansen T, Albrechtsen A. Andersen MK, et al. Among authors: larsen cvl. Gastroenterology. 2022 Apr;162(4):1171-1182.e3. doi: 10.1053/j.gastro.2021.12.236. Epub 2021 Dec 13. Gastroenterology. 2022. PMID: 34914943 Free article.
59 results