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Albumin-based drug delivery: harnessing nature to cure disease.
Larsen MT, Kuhlmann M, Hvam ML, Howard KA. Larsen MT, et al. Mol Cell Ther. 2016 Feb 27;4:3. doi: 10.1186/s40591-016-0048-8. eCollection 2016. Mol Cell Ther. 2016. PMID: 26925240 Free PMC article. Review.
An Albumin-Oligonucleotide Assembly for Potential Combinatorial Drug Delivery and Half-Life Extension Applications.
Kuhlmann M, Hamming JBR, Voldum A, Tsakiridou G, Larsen MT, Schmøkel JS, Sohn E, Bienk K, Schaffert D, Sørensen ES, Wengel J, Dupont DM, Howard KA. Kuhlmann M, et al. Among authors: larsen mt. Mol Ther Nucleic Acids. 2017 Dec 15;9:284-293. doi: 10.1016/j.omtn.2017.10.004. Epub 2017 Oct 7. Mol Ther Nucleic Acids. 2017. PMID: 29246307 Free PMC article.
Cellular recycling-driven in vivo half-life extension using recombinant albumin fusions tuned for neonatal Fc receptor (FcRn) engagement.
Larsen MT, Rawsthorne H, Schelde KK, Dagnæs-Hansen F, Cameron J, Howard KA. Larsen MT, et al. J Control Release. 2018 Oct 10;287:132-141. doi: 10.1016/j.jconrel.2018.07.023. Epub 2018 Aug 29. J Control Release. 2018. PMID: 30016735
FcRn overexpression in human cancer drives albumin recycling and cell growth; a mechanistic basis for exploitation in targeted albumin-drug designs.
Larsen MT, Mandrup OA, Schelde KK, Luo Y, Sørensen KD, Dagnæs-Hansen F, Cameron J, Stougaard M, Steiniche T, Howard KA. Larsen MT, et al. J Control Release. 2020 Jun 10;322:53-63. doi: 10.1016/j.jconrel.2020.03.004. Epub 2020 Mar 4. J Control Release. 2020. PMID: 32145268
Synthesis and inhibitory evaluation of 3-linked imipramines for the exploration of the S2 site of the human serotonin transporter.
Brinkø A, Larsen MT, Koldsø H, Besenbacher L, Kolind A, Schiøtt B, Sinning S, Jensen HH. Brinkø A, et al. Among authors: larsen mt. Bioorg Med Chem. 2016 Jun 15;24(12):2725-38. doi: 10.1016/j.bmc.2016.04.039. Epub 2016 Apr 21. Bioorg Med Chem. 2016. PMID: 27160055
Patients admitted for treatment of traumatic finger amputations: Characteristics, causes, and prevention.
Larsen MT, Eldridge-Allegra I, Wu J, Jain SA. Larsen MT, et al. J Clin Orthop Trauma. 2019 Sep-Oct;10(5):949-953. doi: 10.1016/j.jcot.2019.01.024. Epub 2019 Jan 30. J Clin Orthop Trauma. 2019. PMID: 31528073 Free PMC article.
Increased lipid accumulation but not reduced metabolism explains improved starvation tolerance in cold-acclimated arthropod predators.
Jensen K, Michaelsen JV, Larsen MT, Kristensen TN, Holmstrup M, Overgaard J. Jensen K, et al. Among authors: larsen mt. Naturwissenschaften. 2018 Nov 19;105(11-12):65. doi: 10.1007/s00114-018-1593-6. Naturwissenschaften. 2018. PMID: 30456565
Apheresis principles in a patient with chronic myeloid leukemia during pregnancy: challenges in cell separation and assessing transcript levels.
Lund KP, Larsen MT, Haastrup EK, Pedersen BW, Maroun LL, Andersen MT, Bjerrum OW, Fischer-Nielsen A. Lund KP, et al. Among authors: larsen mt. Transfusion. 2019 Jan;59(1):39-45. doi: 10.1111/trf.15006. Epub 2018 Nov 5. Transfusion. 2019. PMID: 30394539
Human α-defensin expression is not dependent on CCAAT/enhancer binding protein-ε in a murine model.
Glenthøj A, Dahl S, Larsen MT, Cowland JB, Borregaard N. Glenthøj A, et al. Among authors: larsen mt. PLoS One. 2014 Mar 21;9(3):e92471. doi: 10.1371/journal.pone.0092471. eCollection 2014. PLoS One. 2014. PMID: 24658030 Free PMC article.
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