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Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q.
Larsen PL, Clarke CF. Larsen PL, et al. Science. 2002 Jan 4;295(5552):120-3. doi: 10.1126/science.1064653. Science. 2002. PMID: 11778046
Direct and indirect transcriptional targets of DAF-16.
Larsen PL. Larsen PL. Sci Aging Knowledge Environ. 2003 Apr 30;2003(17):PE9. doi: 10.1126/sageke.2003.17.pe9. Sci Aging Knowledge Environ. 2003. PMID: 12844535
Protein-repair and hormone-signaling pathways specify dauer and adult longevity and dauer development in Caenorhabditis elegans.
Banfield KL, Gomez TA, Lee W, Clarke S, Larsen PL. Banfield KL, et al. Among authors: larsen pl. J Gerontol A Biol Sci Med Sci. 2008 Aug;63(8):798-808. doi: 10.1093/gerona/63.8.798. J Gerontol A Biol Sci Med Sci. 2008. PMID: 18772467 Free PMC article.
Altered bacterial metabolism, not coenzyme Q content, is responsible for the lifespan extension in Caenorhabditis elegans fed an Escherichia coli diet lacking coenzyme Q.
Saiki R, Lunceford AL, Bixler T, Dang P, Lee W, Furukawa S, Larsen PL, Clarke CF. Saiki R, et al. Among authors: larsen pl. Aging Cell. 2008 Jun;7(3):291-304. doi: 10.1111/j.1474-9726.2008.00378.x. Epub 2008 Feb 11. Aging Cell. 2008. PMID: 18267002 Free PMC article.
Defective mitochondrial protein translocation precludes normal Caenorhabditis elegans development.
Curran SP, Leverich EP, Koehler CM, Larsen PL. Curran SP, et al. Among authors: larsen pl. J Biol Chem. 2004 Dec 24;279(52):54655-62. doi: 10.1074/jbc.M409618200. Epub 2004 Oct 13. J Biol Chem. 2004. PMID: 15485840
Reproductive fitness and quinone content of Caenorhabditis elegans clk-1 mutants fed coenzyme Q isoforms of varying length.
Jonassen T, Davis DE, Larsen PL, Clarke CF. Jonassen T, et al. Among authors: larsen pl. J Biol Chem. 2003 Dec 19;278(51):51735-42. doi: 10.1074/jbc.M308760200. Epub 2003 Oct 6. J Biol Chem. 2003. PMID: 14530273
Development and fertility in Caenorhabditis elegans clk-1 mutants depend upon transport of dietary coenzyme Q8 to mitochondria.
Jonassen T, Marbois BN, Faull KF, Clarke CF, Larsen PL. Jonassen T, et al. Among authors: larsen pl. J Biol Chem. 2002 Nov 22;277(47):45020-7. doi: 10.1074/jbc.M204758200. Epub 2002 Sep 24. J Biol Chem. 2002. PMID: 12324451
DAF-16-dependent and independent expression targets of DAF-2 insulin receptor-like pathway in Caenorhabditis elegans include FKBPs.
Yu H, Larsen PL. Yu H, et al. Among authors: larsen pl. J Mol Biol. 2001 Dec 14;314(5):1017-28. doi: 10.1006/jmbi.2000.5210. J Mol Biol. 2001. PMID: 11743719
A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-1 mutants.
Jonassen T, Larsen PL, Clarke CF. Jonassen T, et al. Among authors: larsen pl. Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):421-6. doi: 10.1073/pnas.021337498. Epub 2001 Jan 2. Proc Natl Acad Sci U S A. 2001. PMID: 11136229 Free PMC article.
Structure and expression of daf-12: a nuclear hormone receptor with three isoforms that are involved in development and aging in Caenorhabditis elegans.
Snow MI, Larsen PL. Snow MI, et al. Among authors: larsen pl. Biochim Biophys Acta. 2000 Nov 15;1494(1-2):104-16. doi: 10.1016/s0167-4781(00)00224-4. Biochim Biophys Acta. 2000. PMID: 11072073
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