Larsson A - Search Results

1

An efficient proteome-wide strategy for discovery and characterization of cellular nucleotide-protein interactions.

Lim YT, Prabhu N, Dai L, Go KD, Chen D, Sreekumar L, Egeblad L, Eriksson S, Chen L, Veerappan S, Teo HL, Tan CSH, Lengqvist J, Larsson A, Sobota RM, Nordlund P. Lim YT, et al. Among authors: larsson a. PLoS One. 2018 Dec 6;13(12):e0208273. doi: 10.1371/journal.pone.0208273. eCollection 2018. PLoS One. 2018. PMID: 30521565 Free PMC article.

2

Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states.

Chen D, Jansson A, Sim D, Larsson A, Nordlund P. Chen D, et al. Among authors: larsson a. J Biol Chem. 2017 Aug 11;292(32):13449-13458. doi: 10.1074/jbc.M117.787267. Epub 2017 Jun 20. J Biol Chem. 2017. PMID: 28634233 Free PMC article.

3

Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay.

Dziekan JM, Yu H, Chen D, Dai L, Wirjanata G, Larsson A, Prabhu N, Sobota RM, Bozdech Z, Nordlund P. Dziekan JM, et al. Among authors: larsson a. Sci Transl Med. 2019 Jan 2;11(473):eaau3174. doi: 10.1126/scitranslmed.aau3174. Sci Transl Med. 2019. PMID: 30602534

4

Efficiency of hit generation and structural characterization in fragment-based ligand discovery.

Larsson A, Jansson A, Åberg A, Nordlund P. Larsson A, et al. Curr Opin Chem Biol. 2011 Aug;15(4):482-8. doi: 10.1016/j.cbpa.2011.06.008. Epub 2011 Jul 1. Curr Opin Chem Biol. 2011. PMID: 21724447 Review.

5

Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality.

Kitagawa M, Liao PJ, Lee KH, Wong J, Shang SC, Minami N, Sampetrean O, Saya H, Lingyun D, Prabhu N, Diam GK, Sobota R, Larsson A, Nordlund P, McCormick F, Ghosh S, Epstein DM, Dymock BW, Lee SH. Kitagawa M, et al. Among authors: larsson a. Nat Commun. 2017 Dec 19;8(1):2200. doi: 10.1038/s41467-017-02287-5. Nat Commun. 2017. PMID: 29259156 Free PMC article.

6

CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil.

Almqvist H, Axelsson H, Jafari R, Dan C, Mateus A, Haraldsson M, Larsson A, Martinez Molina D, Artursson P, Lundbäck T, Nordlund P. Almqvist H, et al. Among authors: larsson a. Nat Commun. 2016 Mar 24;7:11040. doi: 10.1038/ncomms11040. Nat Commun. 2016. PMID: 27010513 Free PMC article.

7

Predicting Allosteric Effects from Orthosteric Binding in Hsp90-Ligand Interactions: Implications for Fragment-Based Drug Design.

Chandramohan A, Krishnamurthy S, Larsson A, Nordlund P, Jansson A, Anand GS. Chandramohan A, et al. Among authors: larsson a. PLoS Comput Biol. 2016 Jun 2;12(6):e1004840. doi: 10.1371/journal.pcbi.1004840. eCollection 2016 Jun. PLoS Comput Biol. 2016. PMID: 27253209 Free PMC article.

8

Proapoptotic Cyclic Peptide BC71 Targets Cell-Surface GRP78 and Functions as an Anticancer Therapeutic in Mice.

Kao C, Chandna R, Ghode A, Dsouza C, Chen M, Larsson A, Lim SH, Wang M, Cao Z, Zhu Y, Anand GS, Ge R. Kao C, et al. Among authors: larsson a. EBioMedicine. 2018 Jul;33:22-32. doi: 10.1016/j.ebiom.2018.06.004. Epub 2018 Jun 12. EBioMedicine. 2018. PMID: 29907328 Free PMC article.

9

Backbone resonance assignment for the N-terminal region of bacterial tRNA-(N¹G37) methyltransferase.

Li Y, Zhong W, Koay AZ, Ng HQ, Koh-Stenta X, Nah Q, Lim SH, Larsson A, Lescar J, Hill J, Dedon PC, Kang C. Li Y, et al. Among authors: larsson a. Biomol NMR Assign. 2019 Apr;13(1):49-53. doi: 10.1007/s12104-018-9849-9. Epub 2018 Oct 8. Biomol NMR Assign. 2019. PMID: 30298375

10

Modulating release of ranibizumab and aflibercept from thiolated chitosan-based hydrogels for potential treatment of ocular neovascularization.

Moreno M, Pow PY, Tabitha TST, Nirmal S, Larsson A, Radhakrishnan K, Nirmal J, Quah ST, Geifman Shochat S, Agrawal R, Venkatraman S. Moreno M, et al. Among authors: larsson a. Expert Opin Drug Deliv. 2017 Aug;14(8):913-925. doi: 10.1080/17425247.2017.1343297. Epub 2017 Jul 3. Expert Opin Drug Deliv. 2017. PMID: 28643528

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