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Page 1
Tau Phosphorylation-Much More than a Biomarker.
Maeda S, Mucke L. Maeda S, et al. Neuron. 2016 Oct 19;92(2):265-267. doi: 10.1016/j.neuron.2016.10.011. Neuron. 2016. PMID: 27764656 Free article.
Lasagna-Reeves et al. (2016) demonstrate that preventing the kinase Nuak1 from phosphorylating the microtubule-associated protein tau reduces the level of potentially pathogenic tau species in brain, a novel therapeutic strategy that could help counteract Alzheimer' …
Lasagna-Reeves et al. (2016) demonstrate that preventing the kinase Nuak1 from phosphorylating the microtubule-associated prot …
Bassoon contributes to tau-seed propagation and neurotoxicity.
Martinez P, Patel H, You Y, Jury N, Perkins A, Lee-Gosselin A, Taylor X, You Y, Viana Di Prisco G, Huang X, Dutta S, Wijeratne AB, Redding-Ochoa J, Shahid SS, Codocedo JF, Min S, Landreth GE, Mosley AL, Wu YC, McKinzie DL, Rochet JC, Zhang J, Atwood BK, Troncoso J, Lasagna-Reeves CA. Martinez P, et al. Nat Neurosci. 2022 Dec;25(12):1597-1607. doi: 10.1038/s41593-022-01191-6. Epub 2022 Nov 7. Nat Neurosci. 2022. PMID: 36344699 Free PMC article.
Tau aggregates as immunotherapeutic targets.
Castillo-Carranza DL, Lasagna-Reeves CA, Kayed R. Castillo-Carranza DL, et al. Front Biosci (Schol Ed). 2013 Jan 1;5(2):426-38. doi: 10.2741/s381. Front Biosci (Schol Ed). 2013. PMID: 23277060 Free article. Review.
Enhanced microglial dynamics and a paucity of tau seeding in the amyloid plaque microenvironment contribute to cognitive resilience in Alzheimer's disease.
Jury-Garfe N, Redding-Ochoa J, You Y, Martínez P, Karahan H, Chimal-Juárez E, Johnson TS, Zhang J, Resnick S, Kim J, Troncoso JC, Lasagna-Reeves CA. Jury-Garfe N, et al. Acta Neuropathol. 2024 Aug 5;148(1):15. doi: 10.1007/s00401-024-02775-1. Acta Neuropathol. 2024. PMID: 39102080 Free PMC article.
Molecular mechanisms of amyloid oligomers toxicity.
Kayed R, Lasagna-Reeves CA. Kayed R, et al. J Alzheimers Dis. 2013;33 Suppl 1:S67-78. doi: 10.3233/JAD-2012-129001. J Alzheimers Dis. 2013. PMID: 22531422 Free article. Review.
57 results