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Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations.
Houlden H, Baker M, McGowan E, Lewis P, Hutton M, Crook R, Wood NW, Kumar-Singh S, Geddes J, Swash M, Scaravilli F, Holton JL, Lashley T, Tomita T, Hashimoto T, Verkkoniemi A, Kalimo H, Somer M, Paetau A, Martin JJ, Van Broeckhoven C, Golde T, Hardy J, Haltia M, Revesz T. Houlden H, et al. Among authors: lashley t. Ann Neurol. 2000 Nov;48(5):806-8. Ann Neurol. 2000. PMID: 11079548
Regional distribution of amyloid-Bri deposition and its association with neurofibrillary degeneration in familial British dementia.
Holton JL, Ghiso J, Lashley T, Rostagno A, Guerin CJ, Gibb G, Houlden H, Ayling H, Martinian L, Anderton BH, Wood NW, Vidal R, Plant G, Frangione B, Revesz T. Holton JL, et al. Among authors: lashley t. Am J Pathol. 2001 Feb;158(2):515-26. doi: 10.1016/S0002-9440(10)63993-4. Am J Pathol. 2001. PMID: 11159188 Free PMC article.
Systemic amyloid deposits in familial British dementia.
Ghiso JA, Holton J, Miravalle L, Calero M, Lashley T, Vidal R, Houlden H, Wood N, Neubert TA, Rostagno A, Plant G, Revesz T, Frangione B. Ghiso JA, et al. Among authors: lashley t. J Biol Chem. 2001 Nov 23;276(47):43909-14. doi: 10.1074/jbc.M105956200. Epub 2001 Sep 13. J Biol Chem. 2001. PMID: 11557758 Free article.
Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta.
Holton JL, Lashley T, Ghiso J, Braendgaard H, Vidal R, Guerin CJ, Gibb G, Hanger DP, Rostagno A, Anderton BH, Strand C, Ayling H, Plant G, Frangione B, Bojsen-Møller M, Revesz T. Holton JL, et al. Among authors: lashley t. J Neuropathol Exp Neurol. 2002 Mar;61(3):254-67. doi: 10.1093/jnen/61.3.254. J Neuropathol Exp Neurol. 2002. PMID: 11895040
Sporadic and familial cerebral amyloid angiopathies.
Revesz T, Holton JL, Lashley T, Plant G, Rostagno A, Ghiso J, Frangione B. Revesz T, et al. Among authors: lashley t. Brain Pathol. 2002 Jul;12(3):343-57. doi: 10.1111/j.1750-3639.2002.tb00449.x. Brain Pathol. 2002. PMID: 12146803 Free PMC article. Review.
Pathological inclusion bodies in tauopathies contain distinct complements of tau with three or four microtubule-binding repeat domains as demonstrated by new specific monoclonal antibodies.
de Silva R, Lashley T, Gibb G, Hanger D, Hope A, Reid A, Bandopadhyay R, Utton M, Strand C, Jowett T, Khan N, Anderton B, Wood N, Holton J, Revesz T, Lees A. de Silva R, et al. Among authors: lashley t. Neuropathol Appl Neurobiol. 2003 Jun;29(3):288-302. doi: 10.1046/j.1365-2990.2003.00463.x. Neuropathol Appl Neurobiol. 2003. PMID: 12787326
Detecting tau isoforms in archival cases.
de Silva R, Lashley T, Revesz T, Lees A, Powers JM. de Silva R, et al. Among authors: lashley t. Acta Neuropathol. 2004 Feb;107(2):181-2. doi: 10.1007/s00401-003-0795-x. Epub 2003 Dec 2. Acta Neuropathol. 2004. PMID: 14652684 No abstract available.
190 results